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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSSFEGQMAEYPTISIDRFDRENLRARAYFLSHCHKDHMKGLRAPTLKRRLECSLKVYLYCSPVTKELLLTSPKYRFWKK
RIISIEIETPTQISLVDEASGEKEEIVVTLLPAGHCPGSVMFLFQGNNGTVLYTGDFRLAQGEAARMELLHSGGRVKDIQ
SVYLDTTFCDPRFYQIPSREECLSGVLELVRSWITRSPYHVVWLNCKAAYGYEYLFTNLSEELGVQVHVNKLDMFRNMPE
ILHHLTTDRNTQIHACRHPKAEEYFQWSKLPCGITSRNRIPLHIISIKPSTMWFGERSRKTNVIVRTGESSYRACFSFHS
SYSEIKDFLSYLCPVNAYPNVIPVGTTMDKVVEILKPLCRSSQSTEPKYKPLGKLKRARTVHRDSEEEDDYLFDDPLPIP
LRHKVP

The query sequence (length=406) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7sgl:D 406 406 1.0000 1.0000 1.0000 0.0 7abs:A, 7af1:A, 7afs:A, 7afu:A, 7agi:A, 7apv:A, 6tt5:AAA, 6wnl:A, 6wnl:B, 6wo0:A
2 7a1f:L 335 355 0.2586 0.3134 0.2958 7.98e-28 7a1f:A, 5aho:A
3 8c8b:A 341 351 0.2537 0.3021 0.2934 1.22e-21 5ahr:A, 4b87:A, 8c8d:A, 8c8s:A, 8cew:A, 8cf0:A, 8cg9:A, 5nzw:A, 5nzx:A, 5nzy:A, 5q1j:A, 5q1k:A, 5q1l:A, 5q1m:A, 5q1n:A, 5q1o:A, 5q1p:A, 5q1q:A, 5q1r:A, 5q1s:A, 5q1t:A, 5q1u:A, 5q1v:A, 5q1w:A, 5q1x:A, 5q1y:A, 5q1z:A, 5q20:A, 5q22:A, 5q23:A, 5q24:A, 5q25:A, 5q26:A, 5q27:A, 5q28:A, 5q29:A
4 7ev5:A 209 132 0.0985 0.1914 0.3030 0.040
5 3tzw:A 467 65 0.0542 0.0471 0.3385 0.078 3tzx:B, 3tzx:A, 3tzy:B, 3tzy:A, 3tzz:B, 3tzz:A
6 8gyg:B 305 143 0.0961 0.1279 0.2727 0.27 8gyg:A
7 8rbx:k 552 71 0.0394 0.0290 0.2254 0.43 7pks:k, 8rbz:k
8 7ycx:K 590 71 0.0394 0.0271 0.2254 0.44 7cun:K, 8r22:C, 8r23:C, 8r2d:C, 8rc4:k, 8uib:K
9 7sn8:K 588 115 0.0616 0.0425 0.2174 0.57 8uic:K
10 4xww:A 545 183 0.0961 0.0716 0.2131 0.57 4xwt:A, 4xwt:B, 4xww:B
11 7l0b:A 202 136 0.0887 0.1782 0.2647 0.58 7l0b:B, 7l0b:C, 7l0b:D
12 8yhe:H 524 122 0.0887 0.0687 0.2951 0.83 8yhd:H
13 6i1d:A 458 133 0.0862 0.0764 0.2632 0.84
14 3a4y:A 431 25 0.0296 0.0278 0.4800 0.99 3a4y:B, 3a4y:C, 3a4y:D, 2dkf:A, 2dkf:B, 2dkf:C, 2dkf:D, 3idz:A, 3idz:B, 3idz:C, 3idz:D, 3ie0:A, 3ie0:B, 3ie0:C, 3ie0:D, 3ie1:A, 3ie1:B, 3ie1:C, 3ie1:D, 3ie2:A, 3ie2:B, 3ie2:C, 3ie2:D, 3iek:A, 3iek:B, 3iek:C, 3iek:D, 3iel:A, 3iel:B, 3iel:C, 3iel:D, 3iem:A, 3iem:B, 3iem:D, 3iem:C
15 2i7t:A 404 118 0.0788 0.0792 0.2712 1.2
16 2i7v:A 433 118 0.0788 0.0739 0.2712 1.2 8t1q:A, 8t1r:A
17 3v00:C 353 133 0.0788 0.0907 0.2406 1.5 1fqj:A, 1fqj:D, 1fqk:A, 1fqk:C, 1got:A, 7jsn:E, 7jsn:F, 1tad:A, 1tad:B, 1tad:C, 1tag:A, 1tnd:A, 1tnd:B, 1tnd:C, 3v00:B, 3v00:A
18 4dnr:A 1031 74 0.0443 0.0175 0.2432 1.9 3k0i:A, 7kf6:A, 7kf6:B, 7kf6:C, 7kf7:B, 7kf8:B, 7kf8:C, 3t53:A
19 3d36:B 221 59 0.0394 0.0724 0.2712 1.9 3d36:A
20 8cuy:A 1016 44 0.0394 0.0157 0.3636 2.0
21 6v4x:H 499 25 0.0296 0.0240 0.4800 2.1 6m8q:A, 6m8q:B
22 2az4:B 426 115 0.0813 0.0775 0.2870 2.6 2az4:A
23 8bmw:N 251 94 0.0665 0.1076 0.2872 3.0
24 6udj:O 108 63 0.0493 0.1852 0.3175 3.1 6udj:I, 6udj:E
25 6q55:A 461 25 0.0296 0.0260 0.4800 4.1 6q5a:A
26 7w1y:F 643 84 0.0542 0.0342 0.2619 5.1 7w1y:7
27 6x6x:A 417 117 0.0665 0.0647 0.2308 5.5 2wn6:A, 2wn7:A, 6x6r:A, 6x6r:B, 6x6v:A, 6x6v:B, 6x6v:C, 6x6v:D, 6x6x:B
28 5a0t:A 454 193 0.1182 0.1057 0.2487 5.7 5a0t:B, 5a0v:A, 5a0v:B
29 2vfr:A 418 59 0.0419 0.0407 0.2881 7.6 2vfs:A, 2vft:A, 2vfu:A, 2vfv:A
30 5ikf:A 150 37 0.0296 0.0800 0.3243 7.8
31 1xcj:A 229 54 0.0394 0.0699 0.2963 8.1 1khh:A, 1khh:B, 1p1b:A, 1p1b:B, 1p1b:C, 1p1b:D, 1p1c:A, 1p1c:B, 1xcl:A
32 4ad9:A 288 34 0.0320 0.0451 0.3824 8.7 4ad9:B, 4ad9:C, 4ad9:D, 4ad9:E, 4ad9:F
33 4h03:A 414 109 0.0567 0.0556 0.2110 8.9 3buz:A, 1giq:A, 1giq:B, 1gir:A, 4h0t:A, 4h0v:A, 4h0x:A, 4h0y:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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