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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSREEVESLIQEVLEVYPEKARKDRNKHLAVNDPAVTQSKKAIISNKKSQPGLMTIRGCAYAGSKGVVWGPIKDMIHISH
GPVGCGQYSRAGRRNYYIGTTGVNAFVTMNFTSDFQEKDIVFGGDKKLAKLIDEVETLFPLNKGISVQSECPIGCIGDDI
ESVSKVKGAELSKTIVPVRCEGFRGVSQSLGHHIANDAVRDWVLGKRDEDTTFASTPYDVAIIGDYNIGGDAWSSRILLE
EMGLRCVAQWSGDGSISEIELTPKVKLNLVHCYRSMNYISRHMEEKYGIPWMEYNFFGPTKTIESLRAIAAKFDESIQKK
CEEVIAKYKPEWEAVVAKYRPRLEGKRVMLYIGGLRPRHVIGAYEDLGMEVVGTGYEFAHNDDYDRTMKEMGDSTLLYDD
VTGYEFEEFVKRIKPDLIGSGIKEKFIFQKMGIPFRQMHSWDYSGPYHGFDGFAIFARDMDMTLNNPCWKKLQAPWE

The query sequence (length=477) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4xpi:A 479 477 0.9937 0.9896 0.9937 0.0 2afh:A, 2afh:C, 2afi:A, 2afi:C, 2afi:I, 2afi:K, 6bbl:A, 6bbl:C, 8bts:A, 8bts:C, 8bts:H, 8bts:J, 5bvg:A, 5bvg:C, 5bvh:A, 5bvh:C, 6cdk:A, 6cdk:C, 8crs:A, 8crs:C, 5cx1:A, 5cx1:C, 5cx1:E, 5cx1:G, 5cx1:I, 5cx1:K, 5cx1:M, 5cx1:O, 8dbx:A, 8dbx:C, 8dby:A, 8dby:C, 8dfc:A, 8dfc:C, 8dfd:A, 8dfd:C, 8dpn:A, 8dpn:C, 8e3t:A, 8e3t:C, 8e3u:A, 8e3u:C, 8e3v:A, 8e3v:C, 8enl:A, 8enm:A, 8enm:C, 8enn:A, 8enn:C, 8eno:A, 1fp4:A, 1fp4:C, 1g20:A, 1g20:C, 1g21:A, 1g21:C, 7jrf:A, 7jrf:C, 3k1a:A, 3k1a:C, 1m1n:A, 1m1n:C, 1m1n:E, 1m1n:G, 1m1y:A, 1m1y:C, 1m1y:I, 1m1y:K, 1m34:A, 1m34:C, 1m34:I, 1m34:K, 7mci:A, 7mci:C, 2min:A, 2min:C, 3min:A, 3min:C, 1n2c:A, 1n2c:C, 4nd8:A, 4nd8:C, 6o7l:A, 6o7l:C, 6o7m:A, 6o7m:C, 6o7n:A, 6o7n:C, 6o7o:A, 6o7o:C, 6o7p:A, 6o7p:C, 6o7q:A, 6o7q:C, 6o7r:A, 6o7r:C, 6o7s:A, 6o7s:C, 6op1:A, 6op1:C, 6op2:A, 6op2:C, 6op3:A, 6op3:C, 6op4:A, 6op4:C, 8p8g:A, 8p8g:C, 4tku:A, 4tku:C, 4tkv:A, 4tkv:C, 3u7q:A, 3u7q:C, 6ug0:A, 6ug0:C, 7ut6:A, 7ut6:C, 7ut7:A, 7ut7:C, 7ut8:A, 7ut8:C, 7ut9:A, 7ut9:C, 7uta:A, 7uta:C, 5vq4:A, 5vq4:C, 6vxt:A, 6vxt:C, 4wna:A, 4wna:C, 4wza:A, 4wza:C, 4wzb:A, 4wzb:C, 4xpi:C
2 8eno:C 407 432 0.8428 0.9877 0.9306 0.0 1l5h:A
3 1h1l:A 478 469 0.7296 0.7280 0.7420 0.0 1h1l:C, 1qgu:A, 1qgu:C, 1qh1:A, 1qh1:C, 1qh8:A, 1qh8:C
4 8enl:C 382 433 0.7966 0.9948 0.8776 0.0
5 5koh:A 483 472 0.7212 0.7122 0.7288 0.0 5koh:C, 5koj:A, 5koj:C
6 5vpw:C 495 503 0.4067 0.3919 0.3857 1.16e-121
7 1mio:A 525 526 0.4088 0.3714 0.3707 9.14e-119 1mio:C, 5vpw:A, 5vq3:A, 5vq3:C, 4wes:A, 4wes:C, 4wn9:A, 4wn9:C
8 7adr:A 473 451 0.3145 0.3171 0.3326 7.57e-81 7adr:D, 7ady:A, 7ady:D, 7aiz:A, 7aiz:D, 6fea:A, 6fea:D, 5n6y:A, 5n6y:D
9 3pdi:A 427 434 0.2830 0.3162 0.3111 4.66e-69 3pdi:C, 3pdi:E, 3pdi:G
10 8oie:A 520 419 0.2956 0.2712 0.3365 5.04e-69 8oie:F
11 8boq:A 515 462 0.3124 0.2893 0.3225 6.83e-66 8boq:D
12 3aer:D 421 241 0.1237 0.1401 0.2448 5.07e-05 3aek:B, 3aek:D, 3aeq:B, 3aeq:D, 3aer:B, 3aes:B, 3aes:D, 3aet:B, 3aet:D, 3aeu:D
13 8boq:B 461 465 0.2306 0.2386 0.2366 5.35e-05 8boq:E
14 8oie:C 456 219 0.1153 0.1206 0.2511 3.71e-04 8oie:H, 8pbb:B, 8pbb:D
15 7adr:E 466 134 0.0734 0.0751 0.2612 3.75e-04 7adr:B, 7ady:B, 7ady:E, 7aiz:B, 7aiz:E, 6fea:B, 6fea:E, 5n6y:B, 5n6y:E
16 2ynm:D 488 191 0.1111 0.1086 0.2775 8.51e-04
17 5jip:A 317 114 0.0671 0.1009 0.2807 1.7 5jip:B
18 3j8g:X 418 67 0.0440 0.0502 0.3134 2.5
19 2w6i:G 263 95 0.0503 0.0913 0.2526 2.6
20 3k2s:A 243 124 0.0566 0.1111 0.2177 4.1 6cch:A, 3k2s:B, 7rsc:D, 7rsc:E, 7rse:D, 7rse:E, 6w4e:D
21 1qd1:B 325 94 0.0440 0.0646 0.2234 4.6 1qd1:A
22 8x6f:C 1153 62 0.0419 0.0173 0.3226 6.6
23 4jxt:A 130 32 0.0273 0.1000 0.4062 7.6
24 5y6p:a8 362 39 0.0294 0.0387 0.3590 9.8 5y6p:a9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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