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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSLVKLANTCAHLQNCSKVRVALTSIPYTKLQLQFAYNLYQQGFLSSLQKGSTMGPDKDFVEVTPDNISTRRLWVGLKYR
DNKPVLSSCKLISKPNSRIHLPMEDMKKLCSGVTIRNIKPLQPGELILVRAHNNIMDINEAISKKLDGEVLCRVK

The query sequence (length=155) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8d8j:H 155 155 1.0000 1.0000 1.0000 1.33e-114 8d8k:H, 8d8l:H, 5mrc:HH, 5mre:HH, 5mrf:HH, 8om2:H, 8om3:H, 8om4:H
2 6yw5:HH 160 157 0.3935 0.3812 0.3885 4.27e-34 6ywe:HH, 6ywx:HH, 6ywy:HH
3 8cd1:h 129 149 0.2387 0.2868 0.2483 1.01e-09 6spc:h, 6spe:h, 6spf:h, 6spg:h, 7unr:h, 7unu:h, 7unv:h, 7unw:h
4 8buu:h 131 150 0.2516 0.2977 0.2600 4.41e-08 8cdu:I, 8cdv:I, 8cec:I, 8ced:I, 8cee:I, 6ha1:h, 6ha8:h, 6htq:h, 3j9w:AH, 5njt:H, 7o5b:H, 8qcq:h, 7qgu:m, 7qh4:l, 8qpp:H, 7qv1:h, 7qv2:h, 7qv3:h, 8r55:H
5 4a2i:H 129 149 0.2258 0.2713 0.2349 6.61e-07 8a3l:H, 7abz:m, 7ac7:m, 7acj:m, 7acr:m, 4adv:H, 5afi:h, 7afi:H, 7afl:H, 7afo:H, 8akn:I, 8am9:I, 6awb:K, 6awc:K, 6awd:K, 9ax7:H, 9ax8:h, 8aye:H, 8b0x:H, 7b5k:h, 8b7y:P, 8bf7:l, 8bge:l, 8bgh:l, 8bh4:l, 8bhj:l, 8bhl:l, 8bhn:l, 8bhp:l, 8bil:l, 8bim:l, 7bod:H, 7boe:H, 7bof:H, 7bog:H, 7boh:H, 7boi:H, 6bu8:H, 6by1:AH, 6by1:BH, 6c4i:h, 8cai:H, 8cep:H, 8cgj:H, 8cgr:H, 8cgu:H, 9cg5:H, 9cg6:H, 9cg7:H, 7cpj:h, 7d6z:o, 7d80:I, 6dnc:UA, 8eiu:H, 8ekc:h, 8emm:H, 6enf:h, 6enj:h, 6enu:h, 8eyq:H, 8eyt:H, 9fbv:H, 8fiz:AQ, 8fto:H, 8fzd:h, 8fze:h, 8fzf:h, 8fzg:h, 8fzh:h, 8fzi:h, 8fzj:h, 8g2u:g, 8g31:g, 8g34:g, 8g38:g, 8g6w:H, 8g7p:h, 8g7q:h, 8g7r:h, 8g7s:h, 8ghu:h, 6gwt:h, 6gxm:h, 6gxn:h, 6gxo:h, 6gxp:h, 6h4n:h, 5h5u:o, 6h58:h, 6h58:hh, 6hrm:m, 8hsp:H, 8htz:H, 8hu1:H, 6i7v:AH, 6i7v:BH, 8ifb:H, 8ifc:H, 5iqr:m, 5it8:AH, 5it8:BH, 3iy8:H, 5j5b:AH, 5j5b:BH, 5j7l:AH, 5j7l:BH, 5j88:AH, 5j88:BH, 5j8a:AH, 5j8a:BH, 3j9y:h, 3j9z:SH, 5j91:AH, 5j91:BH, 3ja1:SH, 3jbu:H, 3jbv:H, 3jcd:h, 3jce:h, 3jcj:p, 3jcn:k, 5jc9:AH, 5jc9:BH, 7jss:M, 7jsw:M, 7jsz:M, 8jsg:p, 8jsh:p, 5jte:AH, 7jt1:M, 7jt2:M, 7jt3:M, 5ju8:AH, 7k00:H, 8k3o:H, 8k4e:H, 7k50:M, 7k51:M, 7k52:M, 7k53:M, 7k54:M, 7k55:M, 5kcr:1h, 5kcs:1h, 5kps:13, 5kpv:12, 5kpw:12, 5kpx:12, 5l3p:h, 6lkq:G, 7lv0:M, 5lza:h, 5lzb:h, 5lzc:h, 5lzd:h, 5lze:h, 5lzf:h, 7m5d:m, 5mdv:m, 5mdw:m, 5mdy:m, 5mdz:m, 5me0:H, 5me1:H, 5mgp:h, 5my1:H, 7n1p:SH, 7n2c:SH, 7n2u:SH, 7n2v:SH, 7n30:SH, 7n31:SH, 7nar:H, 7nas:H, 7nat:H, 7nau:H, 7nav:H, 7nax:H, 7nbu:H, 5no2:H, 5no3:H, 5no4:H, 5np6:K, 6nqb:H, 7nso:h, 7nsp:h, 7nsq:h, 5nwy:7, 7nwt:m, 7nww:l, 7o19:AH, 7o1a:AH, 7o1c:AH, 5o2r:h, 7o5h:H, 6o7k:p, 6o9j:h, 6o9k:h, 7oe0:H, 7oe1:H, 6ofx:M, 6og7:M, 6ogf:M, 6ogg:M, 6ogi:M, 7oi0:H, 7oif:l, 7oig:l, 7oii:l, 7oiz:H, 7oj0:H, 6om6:m, 6ore:m, 6orl:m, 6osk:m, 6osq:m, 6ost:m, 6ot3:m, 7ot5:l, 7otc:h, 6ouo:m, 8p16:m, 8p17:m, 8p18:m, 7p3k:H, 8peg:H, 8phj:H, 7pjs:h, 7pjt:h, 7pju:h, 7pjv:h, 7pjw:h, 7pjx:h, 7pjy:h, 7pjz:h, 8pkl:H, 8pva:H, 7q4k:AH, 8q4f:H, 6q97:m, 6q98:m, 6q9a:m, 8qbt:p, 7qg8:7, 7qgh:7, 7qgn:7, 7qgr:7, 8qk7:m, 8qoa:H, 8r3v:H1, 8r3v:H2, 8r6c:H, 8r8m:H, 8rcl:H1, 8rcl:H2, 8rcm:H1, 8rcm:H2, 8rcs:H1, 8rcs:H2, 8rct:H1, 8rct:H2, 1s03:H, 1s03:G, 7s1g:o, 7s1h:o, 7s1i:o, 7s1j:o, 7s1k:o, 7sa4:m, 7ss9:M, 7ssd:M, 7ssl:M, 7ssn:M, 7sso:M, 7ssw:M, 7st2:M, 7st6:M, 7st7:M, 8syl:h, 6szs:h, 8t5d:g, 8t5h:g, 6tbv:S081, 6tc3:S081, 7tos:S08, 4u1u:AH, 4u1u:CH, 4u1v:AH, 4u1v:CH, 4u20:AH, 4u20:CH, 4u24:AH, 4u24:CH, 4u25:AH, 4u25:CH, 4u26:AH, 4u26:CH, 4u27:AH, 4u27:CH, 5u4i:h, 5u9f:H, 5u9g:H, 7ug7:SH, 7uph:c, 8upo:N, 8upr:N, 8uql:N, 8uqm:N, 8uqp:N, 8ur0:N, 8urh:N, 8uri:N, 8urx:N, 8ury:N, 5uyk:H, 5uyl:H, 5uym:H, 5uyn:H, 5uyp:H, 5uyq:H, 5uz4:H, 4v4h:AH, 4v4h:CH, 4v4q:AH, 4v4q:CH, 4v4v:AH, 4v4w:AH, 4v50:AH, 4v50:CH, 4v52:AH, 4v52:CH, 4v53:AH, 4v53:CH, 4v54:AH, 4v54:CH, 4v55:AH, 4v55:CH, 4v56:AH, 4v56:CH, 4v57:AH, 4v57:CH, 4v5b:BH, 4v5b:DH, 4v5h:AH, 4v5y:AH, 4v5y:CH, 4v64:AH, 4v64:CH, 4v65:AV, 4v66:AV, 4v69:AH, 4v6c:AH, 4v6c:CH, 4v6d:AH, 4v6d:CH, 4v6e:AH, 4v6e:CH, 4v6k:BL, 4v6l:AL, 4v6m:AH, 4v6n:BK, 4v6o:AK, 4v6p:AK, 4v6q:AK, 4v6r:AK, 4v6s:BJ, 4v6t:AH, 4v6v:AH, 4v6y:AH, 4v6z:AH, 4v70:AH, 4v71:AH, 4v72:AH, 4v73:AH, 4v74:AH, 4v75:AH, 4v76:AH, 4v77:AH, 4v78:AH, 4v79:AH, 4v7a:AH, 4v7b:AH, 4v7c:AH, 4v7d:BH, 4v7i:BH, 4v7s:AH, 4v7s:CH, 4v7t:AH, 4v7t:CH, 4v7u:AH, 4v7u:CH, 4v7v:AH, 4v7v:CH, 4v85:AH, 4v89:AH, 4v9c:AH, 4v9c:CH, 4v9d:AH, 4v9d:BH, 4v9o:BH, 4v9o:DH, 4v9o:FH, 4v9o:HH, 4v9p:BH, 4v9p:DH, 4v9p:FH, 4v9p:HH, 8vs9:S08, 8vsa:S08, 6vu3:N, 6vwl:g, 6vwm:g, 6vwn:g, 6vyq:N, 6vyr:N, 6vys:N, 6vyt:N, 6vyu:N, 6vyw:N, 6vyx:N, 6vyy:N, 6vyz:N, 6vz2:N, 6vz3:N, 6vz5:N, 6vz7:N, 6vzj:N, 6w6k:H, 6w77:H, 6w7m:H, 6w7n:H, 6w7w:G, 5wdt:h, 6wd0:M, 6wd1:M, 6wd2:M, 6wd3:M, 6wd4:M, 6wd5:M, 6wd6:M, 6wd7:M, 6wd8:M, 6wd9:M, 6wda:M, 6wdb:M, 6wdc:M, 6wdd:M, 6wde:M, 6wdf:M, 6wdg:M, 6wdh:M, 6wdi:M, 6wdj:M, 6wdk:M, 6wdl:M, 6wdm:M, 5we4:h, 5we6:h, 4wf1:AH, 4wf1:CH, 5wf0:h, 5wfk:h, 5wfs:h, 6wnv:M, 6wnw:M, 4woi:AH, 4woi:DH, 4www:QH, 4www:XH, 6x6t:N, 6x7f:N, 6x7k:N, 6x9q:N, 6xdq:N, 6xdr:N, 6xe0:G, 6xgf:N, 6xii:N, 6xij:N, 6xza:H1, 6xzb:H1, 6y69:h, 7y7c:H, 7y7d:H, 7y7e:H, 7y7f:H, 7y7g:H, 7y7h:H, 4ybb:AH, 4ybb:BH, 2ykr:H, 6ysr:h, 6yss:h, 6yst:h, 6ysu:h, 6ztj:AH, 6ztl:AH, 6ztm:AH, 6ztn:AH, 6zto:AH, 6ztp:AH, 7zta:S081, 6zu1:AH
6 7m4u:h 130 149 0.2258 0.2692 0.2349 9.01e-06 7m4w:h, 7m4x:h, 7m4y:h, 7m4z:h, 7ryf:h, 7ryg:h, 7ryh:h, 7uvv:h, 7uvw:h, 7uvx:h, 7uvy:h, 7uvz:h, 7uw1:h, 6v39:h, 6v3a:h, 6v3b:h, 6v3e:h, 6ypu:i, 6yt9:i
7 7ooc:G 141 151 0.2258 0.2482 0.2318 1.13e-04 7p6z:G, 7pah:G, 7pai:G, 7paj:G, 7pak:G, 7pal:G, 7pam:G, 7pan:G, 7pao:G, 7paq:G, 7par:G, 7pas:G, 7ph9:G, 7pha:G, 7phb:G, 7phc:G, 7pi8:G, 7pi9:G, 7pia:G, 7pib:G, 7pic:G, 7pio:G, 7pip:G, 7piq:G, 7pir:G, 7pis:G, 7pit:G
8 8crx:H 134 150 0.2000 0.2313 0.2067 0.002 8cwo:H
9 8fmw:H 132 151 0.2194 0.2576 0.2252 0.004
10 8rd8:BQ 131 143 0.2194 0.2595 0.2378 0.026 8rdv:BQ, 8rdw:BQ
11 7jil:m 131 151 0.2065 0.2443 0.2119 0.042
12 6dzi:q 131 150 0.1806 0.2137 0.1867 0.047 6dzk:H, 8fr8:i, 7kgb:h, 7msc:h, 7msh:h, 7msm:h, 7msz:h, 7mt2:h, 7mt3:h, 7mt7:h, 5o5j:H, 5o61:BH, 7sfr:h, 5v93:h, 8v9j:h, 8v9k:h, 8v9l:h, 8whx:i, 8wi7:i, 8wi9:i, 8wib:i, 8wid:i, 8wif:i, 5xyu:H, 5zeb:h, 5zep:h, 5zeu:h
13 6z42:A 336 81 0.1419 0.0655 0.2716 1.00 6z42:B, 6z42:C, 6z42:D
14 4iv8:A 245 40 0.1032 0.0653 0.4000 1.2 4iv8:B
15 5yvg:B 764 63 0.1484 0.0301 0.3651 1.5
16 8sgh:A 844 63 0.1484 0.0273 0.3651 1.6 7cyl:A, 4fdd:A, 4fq3:A, 2h4m:A, 5j3v:A, 5j3v:B, 4jlq:A, 4oo6:A, 2ot8:A, 5tqc:A, 7vpw:A, 5yvi:A, 2z5k:A, 2z5m:A, 2z5n:A, 2z5o:A
17 5yvg:A 830 63 0.1484 0.0277 0.3651 1.6 2h4m:B, 2ot8:B, 5yvh:A
18 4mwz:B 265 40 0.1032 0.0604 0.4000 2.1 4iv0:A, 4iv0:B, 4mwz:A
19 2ac3:A 277 55 0.1032 0.0578 0.2909 3.0 2ac5:A, 6cj5:A, 6cje:A, 6cjh:A, 6cjw:A, 6cjy:A, 6ck3:A, 6ck6:A, 6cki:A, 2hw7:A, 6jlr:A, 8p9b:A, 8xfm:A
20 6t9w:B 383 29 0.0968 0.0392 0.5172 5.1 8bxx:AA, 8bxx:BB, 8bxx:CC, 8bxx:DD, 6t9w:A, 6t9w:C, 6t9x:B, 6t9x:A, 6t9x:C, 6t9x:D, 6tb6:B
21 2m0v:A 128 45 0.0839 0.1016 0.2889 6.9
22 5zai:C 259 53 0.1097 0.0656 0.3208 8.0 5zai:A, 5zai:B, 5zai:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218