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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSKISVTVNGRRYPWPRVPAIAVCLDGCEPAYLDAAIDAGLMPALKRIKERGAVRLAHSVIPSFANPNNLSIATGSPPAV
HGICGNYLYEPSTGEEVMMNDPKFLRAPTIFQAFYDAGARVAVVTAKDKLRALLGKGLRFDEGRAVCFSSEKSDKATRAE
HGIDNASAWLGRPVPEVYSAALSEFVFAAGVKLLREFRPDIMYLTTTDYVQHKYAPGVPEANSFYEMFDRYLAELDGLGA
AIVVTADHGMKPKHKADGSPDVIYVQDLLDEWLGKDAARVILPITDPYVVHHGALGSFATAYLPDGCDRSEIMARLKAIQ
GVDVVLGREEACRRFELPEDRIGDIVLVSSENKTLGTSEHRHDLAALDEPLRSHGGLTEQEVPFIVNRVLPELPNAPRLR
NFDAFFYAVTAAA

The query sequence (length=413) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3szy:A 413 413 0.9976 0.9976 0.9976 0.0 3szz:A, 3t00:A, 3t01:A, 3t02:A
2 1ei6:A 404 398 0.5303 0.5421 0.5503 1.50e-157 1ei6:B, 1ei6:C, 1ei6:D
3 6xkd:A 679 244 0.1477 0.0898 0.2500 8.93e-07
4 4gtw:A 706 244 0.1477 0.0864 0.2500 1.19e-06 4gtw:B, 4gtx:A, 4gtx:B, 4gty:A, 4gty:B, 4gtz:A, 4gtz:B, 6xkd:B
5 4b56:A 816 244 0.1477 0.0748 0.2500 1.73e-06 6aek:A, 6ael:A, 4b56:B
6 6wev:AbA 817 251 0.1525 0.0771 0.2510 2.86e-06 8ghr:A, 8ghr:B, 6wet:AaA, 6wet:BaB, 6weu:AbA, 6weu:BbB, 6wev:BbB, 6wew:AbA, 6wew:BaB, 6wfj:AcA, 6wfj:BcB
7 3way:A 787 247 0.1477 0.0775 0.2470 4.53e-06 8c3o:B, 8c3p:A, 8c3p:B, 8c4w:A, 8c7r:A, 5dlv:A, 5dlv:B, 5dlw:A, 5inh:A, 5l0b:A, 5l0b:B, 5l0e:A, 5l0e:B, 5l0k:A, 5l0k:B, 6leh:A, 5lqq:A, 5m0d:A, 5m0e:A, 5m0m:A, 5m0s:A, 7mfh:A, 5mhp:A, 3nkn:A, 3nko:A, 3nkq:A, 3nkr:A, 5ohi:A, 5olb:A, 7p0k:AAA, 7p4j:A, 7p4o:A, 3waw:A, 6y5m:A, 4zg7:A
8 5s9m:A 809 247 0.1477 0.0754 0.2470 4.68e-06 8c3o:A, 5dlt:A, 9ent:A, 9eu5:A, 5hrt:A, 5ijq:A, 5ijs:A, 5lia:A, 3nkm:A, 3nkp:A, 5s9l:A, 5s9n:A, 6w35:A, 3wav:A, 3wax:A, 2xr9:A, 7z0n:AAA, 7z3k:AAA, 7z3l:AAA
9 2xrg:A 758 247 0.1477 0.0805 0.2470 4.80e-06
10 4zg9:B 764 247 0.1453 0.0785 0.2429 2.05e-05 5kxa:A, 5m7m:A, 4zg6:A, 4zg6:B, 4zg9:A, 4zga:A
11 5gz4:A 804 250 0.1356 0.0697 0.2240 5.41e-04 7cba:A, 7cba:B, 5gz5:A
12 5egh:B 393 76 0.0581 0.0611 0.3158 6.23e-04 5ege:A, 5ege:B, 5ege:C, 5ege:D, 5egh:A
13 7mw8:C 385 140 0.0799 0.0857 0.2357 0.001 2gsn:A, 2gsn:B, 2gso:A, 2gso:B, 2gsu:A, 2gsu:B, 7mw8:A, 7mw8:D, 7mw8:B, 7mw8:E, 7mw8:F, 7n1s:A, 7n1s:B, 2rh6:A, 2rh6:B
14 6f2t:B 722 73 0.0557 0.0319 0.3151 0.003 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
15 6g4g:C 742 73 0.0557 0.0310 0.3151 0.004
16 6g4g:D 781 73 0.0557 0.0294 0.3151 0.004 6g4g:A
17 4lqy:A 379 366 0.1937 0.2111 0.2186 0.013 4lr2:A
18 5tcd:A 388 253 0.1380 0.1469 0.2253 0.021 5udy:A
19 6c01:A 819 106 0.0678 0.0342 0.2642 0.021 6c01:B, 6c02:A, 6c02:B
20 5tj3:A 520 37 0.0363 0.0288 0.4054 0.13 5too:A
21 5tj3:A 520 54 0.0533 0.0423 0.4074 1.6 5too:A
22 6g4g:B 759 50 0.0387 0.0211 0.3200 0.64
23 5xwk:A 530 297 0.1622 0.1264 0.2256 1.3 3q3q:A
24 5xwi:A 503 297 0.1622 0.1332 0.2256 1.3
25 4v5o:AC 229 78 0.0436 0.0786 0.2308 2.1 4bts:AC, 4bts:BC, 4bts:CC, 4bts:DC, 4v5o:BC
26 3egw:A 1244 77 0.0484 0.0161 0.2597 2.8 3ir5:A, 3ir6:A, 3ir7:A, 1q16:A, 1r27:A, 1r27:C, 1siw:A, 1y4z:A, 1y5i:A, 1y5l:A, 1y5n:A
27 5w4c:A 356 52 0.0412 0.0478 0.3269 4.7 5w4c:B
28 7d0p:A 276 77 0.0484 0.0725 0.2597 5.2 7d0o:A, 7d0q:A, 7d0r:A, 7d0s:A, 5gk9:A, 6maj:A, 6mak:A
29 6m5a:A 844 92 0.0508 0.0249 0.2283 6.4
30 9bha:A 793 81 0.0436 0.0227 0.2222 6.5 5a9f:A, 5aga:A, 9bh8:A, 9bh8:B, 9bh9:A, 9bh9:B, 9bha:B, 9c5q:C, 9c5q:A
31 6s1m:A 1010 76 0.0508 0.0208 0.2763 9.3 6s1n:A, 6s1o:A, 6tny:A, 6tnz:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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