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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGFNPGPFDGSQYALKSTASDAAFIAGGDLHYTLFSN
PSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLGLDSPIAQGRDGTVHKVVYGLMSGDSSALQGQIDALLKAVD
PSLSINSTFDQLAAAGVAHATPA

The query sequence (length=183) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7emo:A 186 183 1.0000 0.9839 1.0000 1.89e-130 3ell:A, 3ell:B, 7emo:B, 7emo:C, 7emp:A, 7emp:B, 7emp:C, 7emq:A, 7emq:B, 7emq:C, 7emr:A, 7emr:B, 7emr:C, 7ems:A, 7ems:B, 7ems:C, 7emt:A, 7emu:A, 7emv:A, 7emw:A, 5iqx:A, 6jlg:A, 6jlg:E, 6jlg:B, 6jlg:C, 6jlg:D, 6jlg:F, 6jlg:G, 6jlg:H, 3mol:A, 3mol:B, 3mom:A, 3mom:B, 4o6q:A, 4o6s:A, 4o6t:A, 4o6u:A, 6u87:A, 6urb:A, 6urb:B, 7vf7:A, 7vf7:B, 7vf7:C, 7vf8:A, 7vf8:B, 7vm1:A, 7vm1:B, 7vm1:C, 7vm1:D, 3w8m:A, 3w8o:A, 3w8o:B, 3wah:A, 3wah:B, 5xa4:A, 5xa4:B, 5xhl:A, 5xhl:B, 5xib:A, 5xib:B, 5xic:A, 5xic:B, 5xic:C, 5xic:D, 5xie:A, 5xie:B, 5xkb:A, 5xkb:B
2 8ki1:A 181 182 0.7869 0.7956 0.7912 1.14e-101 8ki0:A, 8ki0:B, 8ki1:B
3 2uyd:X 174 176 0.4973 0.5230 0.5170 1.73e-53 1b2v:A, 5c58:B, 2cn4:A, 2cn4:B, 3ddr:C, 3ddr:D, 1dk0:A, 1dk0:B, 1dkh:A
4 4jet:A 179 184 0.2951 0.3017 0.2935 1.07e-19 4jet:B, 4jet:C, 4jet:D, 4jet:E, 4jet:F, 4jet:G, 4jet:H, 4jet:I, 4jet:J, 4xzd:A, 4xzd:D, 4y1q:A, 4y1q:B, 4y1q:D, 4y1q:G, 4y1q:I, 4y1q:K, 4y1q:M, 4y1q:O
5 4y4s:A 155 179 0.2842 0.3355 0.2905 1.02e-13
6 3m6i:A 358 107 0.1421 0.0726 0.2430 0.43 3m6i:B
7 7yyp:A 597 60 0.1148 0.0352 0.3500 1.1 7yzn:A, 7zag:7, 7zah:7, 7zki:7
8 7jux:A 278 27 0.0601 0.0396 0.4074 3.0 9axh:C, 9axh:D, 7juw:B, 7juy:B, 7juz:A, 7jv0:A, 7jv1:D
9 3ws1:A 360 40 0.0820 0.0417 0.3750 3.7 3wrz:A, 3wrz:B, 3ws0:A, 3ws0:B, 3ws0:C, 3ws1:B, 3ws1:C, 3ws2:A, 3ws2:B, 3ws2:C, 3ws5:B
10 5a4f:L 581 56 0.0984 0.0310 0.3214 4.9 5a4f:M, 5a4i:L, 5a4i:M, 5a4m:L, 5a4m:M, 5adu:L, 5adu:M, 6fpi:L, 6fpi:M, 6fpo:L, 6fpo:M, 6fpw:L, 6fpw:M, 6g7r:L, 6g7r:M, 6g94:L, 6g94:M, 6g94:J, 6g94:K, 6gal:L, 6gal:M, 4gd3:L, 4gd3:M, 4gd3:J, 4gd3:K, 5jrd:L, 5jrd:M, 5lmm:L, 5lmm:M, 5lry:L, 5lry:M, 6rp2:L, 6rp2:M, 4ue3:LLL, 4ue3:MMM, 3uqy:L, 3uqy:M, 3usc:L, 3usc:M, 3use:L, 3use:M
11 7t7u:D 168 55 0.1148 0.1250 0.3818 5.0 4lms:B, 4lms:D, 7t7u:B
12 5brn:B 194 34 0.0601 0.0567 0.3235 5.2 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
13 1bzy:A 214 34 0.0601 0.0514 0.3235 5.6 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
14 6m8n:A 367 50 0.0874 0.0436 0.3200 5.7
15 6s1s:A 367 34 0.0601 0.0300 0.3235 6.3 4hef:A, 6i30:A, 4nk3:A, 4ooy:A, 3s1y:A, 3s22:A, 8sdr:A, 8sds:A, 8sdt:A, 8sdv:A, 6uqs:A, 6uqt:A, 6uqu:A, 6ur3:A, 4wyy:A, 2wzx:A, 2wzz:A, 4wz4:A, 4x68:A, 4x68:B
16 2d6f:D 522 12 0.0546 0.0192 0.8333 7.1 2d6f:C
17 1k6x:A 324 42 0.0765 0.0432 0.3333 8.9 1ti7:A, 2vut:A, 2vut:B, 2vut:C, 2vut:D, 2vut:E, 2vut:F, 2vut:G, 2vut:H, 2vuu:A, 2vuu:B, 2vuu:C, 2vuu:D, 2vuu:E, 2vuu:F, 2vuu:G, 2vuu:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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