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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSIFDKRVNYKPFEYPEVLQFTEAINKAYWVHTEVDFTADTQDFHAHLSLAEKTAVKNSLLAIAQIEVAVKSFWGNIYEH
FPKPEFNGLGSTFAECEFRHSEAYSRLLEVLGYNDEFEKLLDVPVIRRRVDYLSNVLKDTKSQDNRKYMVSLILFSILIE
NVSLFSQFAILLSFTRFKGYMKNVSNIIAWTSIDEQIHANGGIYIINKIREEFPDYFDEETLALVRETVKDSIAVESDIL
DWIFEEGEIESIKKGDLVNFMKFRIDESLKQINIPVIFDVKVEDYKALAWFEEEVFANSLPVEYTKH

The query sequence (length=307) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6cwq:A 308 300 0.9772 0.9740 1.0000 0.0 6cwo:A, 6cwo:B, 6cwp:B, 6cwp:A, 6cwq:B, 8dq4:A, 8dq4:B, 8dq5:A
2 8dq5:B 265 300 0.8599 0.9962 0.8800 0.0
3 5olk:A 395 294 0.4560 0.3544 0.4762 2.92e-100 5olk:B, 5olk:C, 5olk:D, 6sf5:A, 6sf5:B
4 8dq3:D 297 298 0.3974 0.4108 0.4094 6.56e-83 8dq3:A, 8dq3:B, 8dq3:C
5 6y2n:A 306 284 0.2150 0.2157 0.2324 1.59e-09
6 2rcc:C 311 250 0.1792 0.1768 0.2200 2.47e-09 2rcc:B
7 4d8f:B 334 282 0.2117 0.1946 0.2305 1.44e-08 2ani:A, 4d8f:A, 4d8f:C, 4d8f:D, 4d8g:A, 4d8g:B, 4d8g:C, 4d8g:D, 4m1i:A, 4m1i:B, 4m1i:C, 4m1i:D, 1syy:A
8 7aik:A 321 278 0.1987 0.1900 0.2194 3.58e-05 7ail:A, 7q39:AAA, 7q3c:AAA
9 3hf1:B 286 240 0.1759 0.1888 0.2250 4.07e-05 3hf1:A, 2vux:A
10 2o1z:A 288 282 0.1889 0.2014 0.2057 2.12e-04 2o1z:B, 2p1i:A, 2p1i:B, 2p1i:C, 2p1i:D, 2p1i:E, 2p1i:F, 2p1i:G, 2p1i:H
11 1h0n:A 288 242 0.1629 0.1736 0.2066 0.007 1h0o:A, 2uw2:A, 3vpm:A, 3vpm:B, 3vpn:A, 3vpn:B, 3vpo:A, 3vpo:B, 1w68:A, 1w69:A, 1xsm:A
12 5dcs:A 287 227 0.1433 0.1533 0.1938 0.031 5dco:A, 5dcr:A, 5ekb:A, 6f65:A, 6f6b:A, 6f6c:A, 6f6c:B, 6f6e:A, 6f6e:B, 6f6f:A, 6f6g:A, 6f6g:B, 6f6h:A, 6f6h:B, 6f6k:A, 6f6k:B, 6f6l:A, 6f6l:B, 6f6m:A, 6f6m:B, 4hr0:A, 4hr4:A, 6i90:A, 6i92:A, 6i93:A, 6i94:A, 6i95:A, 5omj:A, 5omk:A, 6qjv:A, 6qk0:A, 6qk0:B, 6qk1:A, 6qk2:A, 6qk2:B, 4xb9:A, 4xbv:A, 4xbv:B, 4xbw:A
13 2inn:A 496 141 0.1303 0.0806 0.2837 0.037 2inn:B, 2inp:A, 2inp:B, 3u52:A, 3u52:B
14 2vux:B 255 247 0.1661 0.2000 0.2065 0.062
15 1jk0:A 334 235 0.1531 0.1407 0.2000 0.26
16 7k7m:B 757 80 0.0782 0.0317 0.3000 1.3 7k7m:A, 7n6b:A
17 6ajf:A 901 80 0.0782 0.0266 0.3000 1.5 6ajg:A, 6ajh:A, 6ajj:A, 7c2m:A, 7c2n:A, 6or2:A, 7wnx:A
18 6aji:A 873 80 0.0782 0.0275 0.3000 1.6
19 5c0q:B 457 73 0.0749 0.0503 0.3151 1.8 5c0q:A, 5c0q:C, 5c0q:D
20 7qbk:A 284 123 0.0879 0.0951 0.2195 2.5
21 6f9p:B 289 86 0.0782 0.0830 0.2791 3.3
22 3szv:A 364 32 0.0423 0.0357 0.4062 4.7 2y0k:A
23 7nvh:A 717 69 0.0619 0.0265 0.2754 5.0
24 6qrz:A 274 215 0.1531 0.1715 0.2186 7.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218