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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSICPHIQQVFQNEKSKDGVLKTCNAARYILNHSVPKEKFLNTMKCGTCHEINSGATFMCLQCGFCGCWNHSHFLSHSKQ
IGHIFGINSNNGLLFCFKCEDYIGNIDLINDAILAKYWDDVCTKTMVPSMERRDGLSGLINTCFMSSILQCLIHNPYFIR
HSMSQIHSNNCKVRSPDKCFSCALDKIVHELYGALGFIYLLTCAWKQDAHEFWQFIINQIHQSYVLDLPNAKEVSRANNK
QCECIVHTVFEGSLESSIVNSKTTIDPFLDLSLDIKDKKKLYECLDSFHKKEQAIKQLGIHKLPSVLVLQLKRFEHLLNG
SNRKLDDFIEFPTYLNMKNYCSTVPDIIYELIGIVSHKGTVNEGHYIAFCKISGGQWFKFNDSMVSSISQEEVLKEQAYL
LFYTIRQVN

The query sequence (length=409) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4wa6:D 415 419 0.9878 0.9735 0.9642 0.0 4w4u:D
2 3mhs:A 455 461 0.9829 0.8835 0.8720 0.0 6aqr:A, 4fip:A, 4fip:E, 4fjc:A, 4fk5:A, 6t9l:K, 4w4u:A, 4wa6:A, 4zux:U, 4zux:Z, 4zux:e, 4zux:j
3 4fjc:E 434 447 0.9633 0.9078 0.8814 0.0 3m99:A, 3mhh:A
4 8bs3:A 324 308 0.2225 0.2809 0.2955 8.29e-33 8bs9:A, 8bs9:C
5 2hd5:A 315 319 0.2274 0.2952 0.2915 6.83e-30
6 3nhe:A 338 338 0.2323 0.2811 0.2811 1.06e-27 6dgf:A, 2ibi:A, 3v6c:A, 3v6e:A, 5xu8:A, 5xve:A
7 7r2g:B 351 329 0.2249 0.2621 0.2796 2.81e-25 6cpm:C, 6cpm:D, 6crn:A, 6crn:B, 6crn:C, 6crn:D, 6gh9:A, 6gha:A, 6ml1:A, 6ml1:B, 7r2g:A
8 2y6e:B 339 333 0.2225 0.2684 0.2733 6.95e-25 2y6e:A, 2y6e:C, 2y6e:E, 2y6e:F
9 2y5b:E 325 328 0.2225 0.2800 0.2774 4.88e-24 3i3t:A, 3i3t:C, 3i3t:E, 3i3t:G, 3mtn:A, 3mtn:C, 2y5b:A
10 5k16:B 328 331 0.2298 0.2866 0.2840 7.92e-23 5cvm:A, 5k16:A, 5k1c:A, 5l8h:A, 5l8w:A
11 8xpn:C 327 321 0.2372 0.2966 0.3022 9.30e-23
12 5cvn:B 321 327 0.2200 0.2804 0.2752 2.40e-22 5cvo:B, 5cvo:E, 6jlq:A
13 3n3k:A 355 343 0.2298 0.2648 0.2741 1.26e-19 2gfo:A, 8xpn:A, 8xpn:B
14 5ohk:A 304 327 0.2200 0.2961 0.2752 1.16e-17 5ohn:A, 5ohn:C
15 5k1b:A 264 311 0.2176 0.3371 0.2862 2.73e-17
16 5wch:A 350 315 0.2078 0.2429 0.2698 6.03e-17 5wch:B, 5wch:C, 5wch:D
17 8d1t:A 330 339 0.2152 0.2667 0.2596 4.61e-14 8d0a:A, 5ohp:A
18 5nge:B 313 295 0.1883 0.2460 0.2610 8.68e-14 5vsk:B
19 5gvi:A 326 326 0.2127 0.2669 0.2669 8.68e-14
20 8itn:A 350 321 0.1809 0.2114 0.2305 3.94e-13 8itn:C, 8itp:D, 8itp:B
21 8p14:A 331 277 0.1760 0.2175 0.2599 4.32e-13 8hje:A, 7tuo:A
22 5k1a:A 239 293 0.1883 0.3222 0.2628 1.94e-11 5k1a:C, 5k1a:E, 5k1a:G
23 5n9t:A 357 293 0.1785 0.2045 0.2491 1.95e-11 8d4z:A, 8d4z:B, 6f5h:A, 6f5h:B, 6m1k:A, 6m1k:B, 5n9r:A, 5n9r:B, 5n9t:B, 5nge:A, 5ngf:A, 5ngf:B, 5uqv:A, 5uqv:B, 5uqx:A, 5uqx:B, 6vn2:A, 6vn2:B, 6vn3:A, 6vn3:B, 6vn4:A, 6vn4:B, 6vn5:A, 6vn5:B, 6vn6:A, 6vn6:B, 5vs6:A, 5vs6:B, 5vsb:A, 5vsb:B, 5vsk:A, 5whc:A, 5whc:B, 7xhh:A, 7xhh:B, 7xhk:B
24 7w3u:A 343 316 0.1638 0.1953 0.2120 3.80e-10 7w3r:A, 7w3u:B, 7w3u:C
25 5cht:A 308 132 0.0978 0.1299 0.3030 5.97e-09 5cht:B, 5chv:A, 5chv:B
26 8a9k:D 285 297 0.1760 0.2526 0.2424 2.99e-08 7ay0:D, 7zh4:D
27 9fcj:D 312 318 0.1809 0.2372 0.2327 1.66e-07 7ay0:B, 9fci:D
28 6iil:A 341 155 0.1002 0.1202 0.2645 2.82e-07 6iik:A, 6iik:B, 6iil:B, 6iim:A, 6iim:B, 6iin:A, 6iin:B
29 6h4h:A 458 236 0.1369 0.1223 0.2373 5.90e-07 6h4h:B, 8p1p:A
30 6h4h:A 458 59 0.0513 0.0459 0.3559 0.006 6h4h:B, 8p1p:A
31 3ihp:B 681 374 0.1883 0.1131 0.2059 6.30e-06 6dxh:A, 6dxt:A, 6dxt:B, 2g43:A, 2g43:B, 2g45:A, 2g45:D, 3ihp:A, 7ms5:A, 7ms5:B, 7ms6:A, 7ms7:A, 7ms7:B, 6nft:A, 6nft:B, 6p9g:A
32 7ay1:D 341 134 0.0856 0.1026 0.2612 6.08e-05 8a9j:D, 7ay2:B, 7zh3:D
33 8y6o:U 458 123 0.0831 0.0742 0.2764 1.16e-04 8h6e:4T, 8h6j:4T, 6qw6:U, 6qx9:U
34 8p1q:A 439 233 0.1320 0.1230 0.2318 8.99e-04 8p1p:B, 8p1q:B
35 8p1q:A 439 59 0.0513 0.0478 0.3559 0.004 8p1p:B, 8p1q:B
36 5txk:A 317 324 0.1809 0.2334 0.2284 0.004
37 3c5k:A 108 92 0.0587 0.2222 0.2609 0.025 5b8d:A, 6ce6:A, 6ce8:A, 6cea:A, 6cec:A, 6ced:A, 6cee:A, 6cef:A, 8g43:A, 8g44:A, 8g45:A, 3gv4:A, 5kh3:A, 5kh7:A, 5kh9:A, 3phd:A, 3phd:B, 3phd:C, 3phd:D, 5wbn:A, 5wpb:A, 7zyu:A
38 5g0f:A 110 60 0.0416 0.1545 0.2833 0.049
39 5xsi:A 333 111 0.0807 0.0991 0.2973 0.10 5xsi:B, 5xsn:A, 5xsn:B, 5xsp:A, 5xsp:B, 5xt3:A, 5xt3:B
40 1v7v:A 779 90 0.0660 0.0347 0.3000 0.46 1v7w:A, 1v7x:A
41 7m1q:A 1911 151 0.0782 0.0167 0.2119 2.9
42 8pmi:B 409 110 0.0636 0.0636 0.2364 3.6 8has:A, 8has:B, 8has:C, 8has:D, 8has:E, 8has:F, 8hau:A, 8hau:B, 8hau:C, 8hau:D, 8hau:E, 8hau:F, 8pme:A, 8pmg:A, 8pmg:B, 8pmg:C, 8pmg:D, 8pmg:E, 8pmg:F, 8pmi:A, 8pmi:C, 8pmi:D, 8pmi:E, 8pmi:F, 8pml:A, 8pml:B, 8pml:C, 8pml:D, 8pml:E, 8pml:F, 8pmm:A, 8pmm:B, 8pmm:C, 8pn1:A, 8pn1:B, 8pn1:C, 8pn1:D, 8pn1:E, 8pn1:F, 8pn2:A, 8pn2:B, 8pn2:C, 8pn2:D, 8pn2:E, 8pn2:F, 7y77:A, 7y77:B, 7y77:C
43 7e7o:A 2003 152 0.0782 0.0160 0.2105 5.0 7lkp:A
44 4q8g:B 353 53 0.0440 0.0510 0.3396 6.4 4q8g:A
45 6kcz:A 99 72 0.0538 0.2222 0.3056 6.9
46 6r9j:A 595 53 0.0440 0.0303 0.3396 7.3 6r9o:A
47 5xe0:A 457 33 0.0367 0.0328 0.4545 7.4 5zit:A
48 6l7c:A 253 92 0.0489 0.0791 0.2174 7.6 6l7c:B, 6l7c:C, 6l7c:D, 6l7c:E, 6l7c:F, 6l7c:G, 6l7c:H, 6l7c:I
49 2i50:A 122 54 0.0342 0.1148 0.2593 9.2

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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