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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSGYGLPISQEVAKELAENARKIAAPGKGILAADESTGTIKKRFDSIGVENTEANRAFYRDLLFSTKGLGQYISGAILFE
ETLYQKSPSGVPMVDLLKAEGIIPGIKVDKGLETLPLTDDEKATMGLDGLSERCKKYYEAGARFAKWRAVLSIDPAKGKP
TNLSITEVAHGLARYAAICQANRLVPIVEPEILTDGSHDITVCAEVTERVLAAVFKALNDHHVLLEGALLKPNMVTHGSD
CPKPASHEEIAFYTVRSLKRTVPPALPGVMFLSGGQSEEDASLNLNEMNKMGPHPFQLSFSYGRALQASCLKAWKGVPEN
KAKAQQVLMERARANGEAQLGKYGGGAYVY

The query sequence (length=350) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5tkl:A 350 350 1.0000 1.0000 1.0000 0.0 5tk3:A, 5tkc:A, 5tkn:A, 5tkp:A
2 2eph:D 351 337 0.6714 0.6695 0.6973 8.48e-174 2pc4:D, 4tr9:A, 4tr9:B, 4tr9:C, 4tr9:D
3 6rng:B 334 334 0.6143 0.6437 0.6437 1.15e-144 6rng:G
4 4ald:A 363 339 0.5714 0.5510 0.5900 4.94e-130 6ald:A, 6ald:B, 3dft:A, 3dft:B, 3dft:C, 3dft:D, 3lge:A, 3lge:B, 3lge:C, 3lge:D, 2ot0:A, 2ot0:B, 2ot0:C, 2ot0:D, 2ot1:A, 2ot1:B, 2ot1:C, 2ot1:D, 2quv:A, 2quv:B, 2quv:D, 5tle:A, 5tle:B, 5tle:C, 5tle:D, 5tlh:A, 5tlh:B, 5tlh:C, 5tlh:D, 5tlw:A, 5tlw:B, 5tlw:C, 5tlw:D, 5tlz:A, 5tlz:B, 5tlz:C, 5tlz:D, 3tu9:A, 3tu9:B, 3tu9:C, 3tu9:D, 6xmh:A, 6xmh:B, 6xml:A, 6xml:B, 6xmm:A, 6xmm:B, 6xmo:A, 6xmo:B, 1zai:A, 1zai:B, 1zai:C, 1zai:D, 1zaj:A, 1zaj:B, 1zaj:C, 1zaj:D, 1zal:A, 1zal:B, 1zal:C, 1zal:D
5 1fdj:A 363 338 0.5371 0.5179 0.5562 7.92e-124 1fdj:B
6 3mmt:A 341 334 0.5200 0.5337 0.5449 7.94e-115 3mmt:B, 3mmt:C, 3mmt:D
7 2qdg:A 366 333 0.4686 0.4481 0.4925 9.04e-101 2qap:A, 2qap:B, 2qap:C, 2qap:D, 2qdg:B, 2qdg:C, 2qdg:D, 2qdh:A, 2qdh:B, 2qdh:C, 2qdh:D
8 3mbf:A 337 318 0.3943 0.4095 0.4340 1.62e-82 3mbd:A, 3qrh:A
9 1c7g:A 456 105 0.0743 0.0570 0.2476 0.97 1c7g:B, 1c7g:C, 1c7g:D, 6dur:A, 6dur:B, 6dvx:A, 6dvx:B, 6dyt:A, 6dyt:B, 6dz5:A, 6dz5:B, 6ecg:A, 2ez2:A, 2ez2:B, 7fjk:A, 7fjk:B, 7fjk:C, 7fjk:D, 6mls:A, 6mls:B, 6mme:A, 6mme:B, 6mo3:A, 6mo3:B, 6mpd:A, 6mpd:B, 6mqq:A, 6mqq:B, 6nv8:A, 6nv8:B, 7tcs:A, 7tcs:B, 7tcs:C, 7tcs:D, 7tdl:A, 7tdl:B, 7tdl:C, 7tdl:D, 2tpl:B, 2vlf:A, 2vlf:B, 2vlh:A, 2vlh:B, 2ycn:A, 2ycn:B, 2ycp:A, 2ycp:B, 2ycp:C, 2ycp:D, 2yct:A, 2yct:B, 2yhk:A, 2yhk:B
10 6rqf:J 160 93 0.0714 0.1562 0.2688 2.6 7qrm:B, 7qrm:J, 6rqf:B, 7zyv:J, 7zyv:B
11 4ur3:A 458 72 0.0571 0.0437 0.2778 6.2 5m2g:A, 5m2g:B, 5m8u:A, 5m8u:B, 5m8w:A, 5m8w:B, 5m8x:A, 5m8x:B, 5m8y:A, 5m8y:B, 5m8z:A, 5m8z:B, 5m90:A, 5m90:B, 5m91:A, 5m91:B, 5m92:A, 5m92:B, 5ma0:A, 5ma0:B, 5ma1:A, 5ma1:B, 5ma2:A, 5ma2:B, 5maa:A, 5maa:B, 5obi:A, 5obi:B, 5obp:A, 5obp:B, 4uqu:A, 4uqu:B, 4ur0:A, 4ur0:B, 4ur1:A, 4ur1:B, 4ur2:A, 4ur2:B, 4ur3:B, 4ur3:C, 4ur3:D, 4ur3:E, 4ur3:F
12 4ga6:A 493 142 0.1086 0.0771 0.2676 7.6 4ga4:A, 4ga4:B, 4ga6:B
13 6fzi:B 332 42 0.0514 0.0542 0.4286 9.6 6fzi:A, 6fzi:C, 6fzi:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218