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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSFSDQNLIWIDLEMTGLDPEMHKIIEMATIVTDSELNILAEGPVIAIHQPESELAKMDEWCTTTHTASGLVARVRQSQV
SEEEAIDQTLAFLKQWVPEGKSPICGNSIGQDRRFLYKHMPRLEAYFHYRYIDVSTIKELTRRWQPEVLKEFSKTGSHLA
LDDIRESIAELQFYRKAVFKI

The query sequence (length=181) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6n6a:A 181 181 1.0000 1.0000 1.0000 1.64e-136 6n6c:A, 6n6d:A, 6n6e:A, 6n6f:A, 6n6g:A, 6n6h:A
2 2igi:A 180 180 0.6740 0.6778 0.6778 1.02e-92 2igi:B, 7vh4:C
3 7va2:A 180 176 0.6906 0.6944 0.7102 3.57e-88 7va3:A, 7va3:B, 7va6:A, 7va6:B
4 6a4d:A 184 181 0.5967 0.5870 0.5967 8.78e-80 6a4d:B, 6a4e:A, 6a4e:C, 6a4f:A, 6a4f:B
5 3tr8:A 184 181 0.5912 0.5815 0.5912 7.93e-79 3tr8:B
6 5cy4:C 184 172 0.5801 0.5707 0.6105 5.57e-76 5cy4:A, 5cy4:B, 5cy4:D, 5cy4:E, 5cy4:F
7 6rk6:C 178 172 0.5193 0.5281 0.5465 3.58e-69 6rk6:A, 6rk6:B
8 6sty:A 198 175 0.5028 0.4596 0.5200 1.06e-63 6j7y:B, 6j7z:B, 6j80:B, 6n6i:A, 6n6i:B, 6n6j:A, 6n6j:B, 6n6k:A, 6n6k:B, 6rcl:A, 6rcn:A, 6sty:B, 6sty:E
9 7wik:C 196 174 0.4309 0.3980 0.4483 3.15e-47
10 6rcl:B 148 175 0.4365 0.5338 0.4514 8.28e-47 6j7y:A, 6j7z:A, 6j80:A, 6rcn:B
11 2qxf:A 433 39 0.0718 0.0300 0.3333 1.8
12 4js4:A 468 39 0.0718 0.0278 0.3333 1.8 3c94:A, 4hcb:A, 4hcb:B, 4hcc:A, 4hcc:B, 3hl8:A, 3hp9:A, 4jrp:A, 4jrp:B, 4jrq:A, 4jrq:B, 4js4:B, 4js5:A, 4js5:B
13 6dtn:B 233 103 0.1602 0.1245 0.2816 2.2 5cvd:A, 5cvd:B, 5cve:A, 5cve:B, 5e1b:A, 5e1b:B, 5e1d:A, 5e1d:B, 5e1m:A, 5e1m:B, 5e1o:A, 5e1o:B, 5e2a:A, 5e2a:B, 5e2b:A, 5e2b:B, 2ex4:A, 2ex4:B, 7k3d:B, 7k3d:A, 6kdq:A, 6kdq:B, 6pva:B, 6pvb:B, 7ss1:A, 7ss1:B, 7u1m:A, 7u1m:B, 6wh8:B, 6wh8:A, 6wj7:B
14 6iix:A 323 83 0.1271 0.0712 0.2771 2.4 4mfk:A, 4mfl:A, 4mfp:A, 4mfq:A, 4q36:A, 4q38:A
15 4gw9:A 628 34 0.0773 0.0223 0.4118 2.7 4gw9:B, 4gw9:C, 4gw9:D, 5oy5:A, 5vik:A, 5viq:A, 5viv:A, 4xtq:A
16 5jo9:A 239 56 0.0939 0.0711 0.3036 4.1
17 8gy3:A 440 127 0.1768 0.0727 0.2520 4.3
18 6cd1:A 452 32 0.0663 0.0265 0.3750 5.1 6ccz:A, 6ccz:B, 6cd1:B, 6cd1:C, 6cd1:D, 6cd1:E, 6cd1:F, 6cd1:G, 6cd1:H
19 7ljm:A 348 37 0.0663 0.0345 0.3243 5.2 7ljm:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218