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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MSFDDLHKATERAVIQAVDQICDDFEVTPEKLDELTAYFIEQMEKGLAPPKEGHTLASDKGLPMIPAFVTGSPNGTERGV
LLAADLGGTNFRICSVNLHGDHTFSMEQMKSKIPDDLLDDENVTSDDLFGFLARRTLAFMKKYHPDELAKGKDAKPMKLG
FTFSYPVDQTSLNSGTLIRWTKGFRIADTVGKDVVQLYQEQLSAQGMPMIKVVALTNDTVGTYLSHCYTSDNTDSMTSGE
ISEPVIGCIFGTGTNGCYMEEINKITKLPQELRDKLIKEGKTHMIINVEWGSFDNELKHLPTTKYDVVIDQKLSTNPGFH
LFEKRVSGMFLGEVLRNILVDLHSQGLLLQQYRSKEQLPRHLTTPFQLSSEVLSHIEIDDSTGLRETELSLLQSLRLPTT
PTERVQIQKLVRAISRRSAYLAAVPLAAILIKTNALNKRYHGEVEIGCDGSVVEYYPGFRSMLRHALALSPLGAEGERKV
HLKIAKDGSGVGAALCALVA

The query sequence (length=500) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6pdt:A 500 500 1.0000 1.0000 1.0000 0.0 6pdt:B, 6pdt:C, 6pdt:D
2 3o5b:A 479 476 0.3640 0.3800 0.3824 2.52e-90 3o5b:B, 3o80:A, 3o8m:A
3 3b8a:X 470 491 0.3660 0.3894 0.3727 1.03e-79
4 3hm8:A 441 462 0.3220 0.3651 0.3485 4.03e-71 3hm8:B, 3hm8:C, 3hm8:D
5 6jj7:A 465 498 0.3600 0.3871 0.3614 3.40e-69 6jj7:C, 6jj7:E, 6jj8:C, 6jj8:A, 6jj8:B, 6jj9:C, 6jj9:A, 6jj9:E, 5zqt:A, 5zqt:B, 5zqt:C
6 5hfu:B 897 492 0.3460 0.1929 0.3516 4.63e-68 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
7 5hfu:B 897 501 0.3180 0.1773 0.3174 4.17e-65 5hex:A, 5hex:B, 5hfu:A, 2nzt:A
8 2nzt:B 867 490 0.3440 0.1984 0.3510 2.25e-67
9 2nzt:B 867 498 0.3060 0.1765 0.3072 3.41e-58
10 4qs7:A 455 492 0.3420 0.3758 0.3476 2.62e-66 4qs9:A
11 5hg1:A 867 498 0.3140 0.1811 0.3153 2.23e-65
12 5hg1:A 867 490 0.3280 0.1892 0.3347 5.32e-56
13 1qha:A 903 489 0.3240 0.1794 0.3313 2.45e-65 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
14 1qha:A 903 493 0.3160 0.1750 0.3205 3.35e-56 1bg3:A, 1bg3:B, 1cza:N, 1dgk:N, 4f9o:A, 4f9o:B, 4foe:A, 4foe:B, 4foi:A, 4foi:B, 4fpa:A, 4fpa:B, 4fpb:A, 4fpb:B, 1hkb:A, 1hkb:B, 1hkc:A, 1qha:B
15 1bdg:A 444 491 0.3160 0.3559 0.3218 7.08e-63
16 3idh:A 453 492 0.2940 0.3245 0.2988 9.81e-59 3a0i:X, 4dhy:A, 6e0e:A, 6e0i:A, 3f9m:A, 3fgu:A, 3fr0:A, 3goi:A, 3h1v:X, 3id8:A, 3imx:A, 4iwv:A, 4ixc:A, 4l3q:A, 4mle:A, 4mlh:A, 4no7:A, 3qic:A, 4rch:A, 3s41:A, 7t78:A, 7t78:B, 7t79:A, 7t79:B, 1v4s:A, 3vev:A, 3vey:A, 3vf6:A
17 4dch:A 434 496 0.2860 0.3295 0.2883 1.71e-46 4ise:A, 4isf:A, 4isg:A, 5v4w:A, 5v4x:A
18 6ksr:A 467 498 0.3160 0.3383 0.3173 2.77e-45
19 7zzi:B 467 498 0.2960 0.3169 0.2972 1.46e-43 7zzi:A
20 2yhx:A 457 292 0.1460 0.1597 0.2500 2.91e-07
21 6sh3:A 376 102 0.0460 0.0612 0.2255 0.16 6sh3:B, 6sh3:C, 6sh3:D, 6sh3:E, 6sh3:F, 6sh3:G
22 6e5v:B 447 103 0.0520 0.0582 0.2524 0.27 6bsz:A, 6bsz:B, 6bt5:A, 6bt5:B, 6e5v:A
23 6xrx:A 551 73 0.0480 0.0436 0.3288 0.42
24 8inh:B 454 180 0.0860 0.0947 0.2389 0.70 8inh:A
25 8p5d:LJ0 167 53 0.0300 0.0898 0.2830 2.1 8p60:LJ0, 8p60:KJ0, 7qca:LJ0
26 5nxb:A 644 91 0.0440 0.0342 0.2418 2.8 4ccc:A, 4ccd:A, 4cce:A, 5nxb:B, 4ufh:A, 4ufi:A, 4ufj:A, 4ufk:A, 4ufl:A, 4ufm:A, 6y6s:A, 6y6t:A, 3zr5:A, 3zr6:A
27 4zgl:F 102 62 0.0380 0.1863 0.3065 3.8 4zgl:B, 4zgl:C, 4zgl:H, 4zgl:I
28 4zsi:A 166 67 0.0380 0.1145 0.2836 5.4 4zsi:B, 4zsk:A, 4zsk:B
29 4q5k:A 237 48 0.0340 0.0717 0.3542 6.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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