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TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRYIDDELENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNPSSLGHFKNLIGFKGEVIAADINNPLDLRRLE
KLHFDYLFHQAAVSDTTMLNQELVMKTNYQAFLNLLEIARSKKAKVIYASSAGVYGNTKAPNVVGKNESPENVYGFSKLC
MDEFVLSHSNDNVQVGLRYFNVYGPREFYKEKTASMVLQLALGAMAFKEVKLFEFGEQLRDFVYIEDVIQANVKAMKAQK
SGVYNVGYSQARSYNEIVSILKEHLGDFKVTYIKNFFQKHTQAHIEPTILDLDYTPLYDLESGIKDYLPHIHAI

The query sequence (length=314) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3sxp:D 314 314 1.0000 1.0000 1.0000 0.0 3sxp:A, 3sxp:B, 3sxp:C, 3sxp:E
2 2x6t:G 308 316 0.3025 0.3084 0.3006 3.48e-33 1eq2:B, 1eq2:D, 1eq2:E, 1eq2:F, 1eq2:G, 1eq2:H, 1eq2:I, 1eq2:J, 2x6t:A, 2x6t:B, 2x6t:C, 2x6t:D, 2x6t:E, 2x6t:F, 2x6t:H, 2x6t:I, 2x6t:J, 2x86:A, 2x86:B, 2x86:C, 2x86:D, 2x86:E, 2x86:F, 2x86:G, 2x86:H, 2x86:I, 2x86:J, 2x86:K, 2x86:L, 2x86:M, 2x86:N, 2x86:O, 2x86:P, 2x86:Q, 2x86:R, 2x86:S, 2x86:T
3 4ej0:A 330 267 0.2771 0.2636 0.3258 1.10e-32 4ej0:B, 4ej0:C, 4ej0:D, 4ej0:E, 4ej0:F, 4ej0:G, 4ej0:H, 4ej0:I, 4ej0:J
4 1eq2:A 273 257 0.2643 0.3040 0.3230 2.96e-29 1eq2:C
5 1sb8:A 341 329 0.3217 0.2962 0.3070 1.43e-27 1sb9:A
6 4zrn:A 309 311 0.3121 0.3172 0.3151 8.79e-23 4zrm:A, 4zrm:B, 4zrn:B
7 6dnt:A 310 277 0.2420 0.2452 0.2744 6.25e-22
8 3lu1:A 336 323 0.2962 0.2768 0.2879 3.69e-21 3lu1:B, 3lu1:C, 3lu1:D, 3ru7:A, 3ru7:B, 3ru7:C, 3ru7:D, 3ru9:A, 3ru9:B, 3ru9:C, 3ru9:D, 3rua:A, 3rua:B, 3rua:C, 3rua:D, 3ruc:A, 3ruc:B, 3ruc:C, 3ruc:D, 3rud:A, 3rud:B, 3rud:C, 3rud:D, 3rue:A, 3rue:B, 3rue:S, 3rue:b, 3ruf:A, 3ruf:B, 3ruf:S, 3ruf:b, 3ruh:A, 3ruh:B, 3ruh:C, 3ruh:D
9 6zll:A 321 322 0.3057 0.2991 0.2981 3.84e-21 6zl6:A, 6zl6:B, 6zla:A, 6zla:B, 6zla:C, 6zla:D, 6zld:A, 6zld:B, 6zlj:A, 6zlj:B, 6zlk:A, 6zlk:B, 6zlk:C, 6zlk:D, 6zll:B, 6zll:C, 6zll:D
10 7k3p:A 329 284 0.2739 0.2614 0.3028 3.60e-20 7k3p:B
11 3vps:A 303 257 0.2484 0.2574 0.3035 2.21e-18 3vps:B
12 2hun:A 329 311 0.2548 0.2432 0.2572 3.21e-18 2hun:B
13 2b69:A 312 315 0.2675 0.2692 0.2667 1.28e-17 4gll:A, 4gll:B
14 6wj9:B 308 268 0.2389 0.2435 0.2799 3.13e-17 6wj9:A, 6wja:A, 6wja:B, 6wjb:A, 6wjb:B
15 4lk3:B 274 301 0.2516 0.2883 0.2625 6.17e-16 4lk3:A, 4lk3:C, 4lk3:D, 4lk3:E, 4lk3:F, 4m55:A, 4m55:B, 4m55:C, 4m55:D
16 5z75:A 306 316 0.2548 0.2614 0.2532 1.45e-15 5z75:B, 5z75:D
17 6kv9:A 299 273 0.2293 0.2408 0.2637 8.08e-15 6kvc:A
18 6bwl:A 313 313 0.2739 0.2748 0.2748 1.78e-14
19 5u4q:A 321 326 0.2548 0.2492 0.2454 2.57e-14
20 7cgv:A 310 320 0.2516 0.2548 0.2469 5.97e-14 7cgv:B, 7cgv:C, 7cgv:D
21 6pnl:A 336 270 0.2293 0.2143 0.2667 6.09e-14 6pmh:A
22 1keu:A 361 336 0.2834 0.2465 0.2649 7.96e-14 1g1a:A, 1g1a:B, 1g1a:C, 1g1a:D, 1keu:B, 1kew:A, 1kew:B
23 1ker:B 347 293 0.2357 0.2133 0.2526 8.25e-14 1kep:A, 1kep:B, 1ker:A, 1ket:A, 1ket:B, 1oc2:A, 1oc2:B
24 3ehe:A 290 261 0.2166 0.2345 0.2605 9.11e-14 3ehe:B
25 7epr:B 310 318 0.2452 0.2484 0.2421 1.26e-13 7epr:A, 7epr:C, 7epr:D
26 8du1:A 361 335 0.2707 0.2355 0.2537 1.65e-13 8du1:B, 8du1:C, 8du1:D
27 8vr2:B 321 324 0.2611 0.2555 0.2531 6.14e-13 8vr2:A, 8vr2:C, 8vr2:D
28 8wov:B 341 288 0.2516 0.2317 0.2743 1.06e-12 8wop:A, 8wop:B, 8wov:A, 8wow:A, 8wow:B
29 5u4q:B 304 326 0.2420 0.2500 0.2331 1.12e-12
30 1bxk:B 344 284 0.2611 0.2384 0.2887 2.39e-12 1bxk:A
31 3a1n:A 315 322 0.2484 0.2476 0.2422 3.31e-12 3a1n:B, 3a4v:A, 3a4v:B, 3a9w:A, 3a9w:B, 3ajr:A, 3ajr:B
32 2pzm:A 316 265 0.2197 0.2184 0.2604 4.41e-12 2pzk:A, 2pzk:B, 2pzl:A, 2pzl:B, 2pzm:B
33 7kn1:A 336 273 0.2134 0.1994 0.2454 5.15e-12 7kn1:B
34 2c20:A 329 275 0.2420 0.2310 0.2764 6.08e-12 2c20:B, 2c20:C, 2c20:D, 2c20:E, 2c20:F
35 1orr:A 338 280 0.2548 0.2367 0.2857 7.26e-12 1orr:B, 1orr:C, 1orr:D
36 7xpo:A 344 293 0.2484 0.2267 0.2662 9.87e-12 7xpo:B, 7xpp:B, 7xpp:A, 7xpq:A, 7xpq:B
37 6bi4:C 311 307 0.2229 0.2251 0.2280 1.58e-11 6bi4:B, 6bi4:D, 6bi4:A
38 2c59:A 364 277 0.2261 0.1951 0.2563 5.68e-11 2c54:A, 2c54:B, 2c59:B, 2c5a:A, 2c5a:B, 2c5e:A, 2c5e:B, 8sg0:A, 8sg0:B, 8skb:A, 8skb:B, 8skb:C, 8skb:D
39 2pk3:A 309 269 0.2325 0.2362 0.2714 7.74e-11 2pk3:B
40 2yy7:A 312 320 0.2675 0.2692 0.2625 1.35e-10 2yy7:B
41 4lis:A 364 300 0.2325 0.2005 0.2433 1.45e-10 4lis:B, 4lis:C
42 1a9y:A 338 282 0.2452 0.2278 0.2730 1.81e-10 1a9z:A, 5gy7:A, 5gy7:B, 1kvq:A, 1kvr:A, 1kvs:A, 1kvt:A, 1kvu:A, 1lrj:A, 1lrk:A, 1lrl:A, 1nah:A, 1nai:A, 1uda:A, 1udb:A, 1udc:A, 2udp:A, 2udp:B, 1xel:A
43 1i3k:A 347 300 0.2548 0.2305 0.2667 1.91e-10 1ek5:A, 1ek6:A, 1ek6:B, 1hzj:A, 1hzj:B, 1i3k:B, 1i3l:A, 1i3l:B, 1i3m:A, 1i3m:B, 1i3n:A, 1i3n:B
44 3aw9:A 304 270 0.2229 0.2303 0.2593 5.61e-10 3aw9:B, 3aw9:C, 3icp:A, 3ko8:A
45 2p5u:A 311 275 0.2452 0.2476 0.2800 2.84e-09 2p5u:B, 2p5u:C, 2p5u:D, 2p5y:A
46 1r66:A 322 269 0.2134 0.2081 0.2491 3.39e-09 1r6d:A
47 7eps:A 310 317 0.2261 0.2290 0.2240 4.43e-09 7eps:B, 7eps:C, 7eps:D, 3wmx:A, 3wmx:B, 3wmx:C, 3wmx:D
48 1gy8:C 370 312 0.2166 0.1838 0.2179 9.55e-09 2cnb:A, 2cnb:B, 2cnb:C, 2cnb:D, 1gy8:A, 1gy8:B, 1gy8:D
49 6k0g:A 335 283 0.2229 0.2090 0.2473 2.06e-08 6k0h:A, 6k0i:A
50 1z45:A 674 273 0.2197 0.1024 0.2527 2.99e-08
51 5y1f:A 311 283 0.2070 0.2090 0.2297 4.23e-08 5y1e:A, 5y1g:A
52 4twr:A 325 282 0.2325 0.2246 0.2589 7.29e-08 4wok:A
53 6x3b:A 300 267 0.2134 0.2233 0.2509 1.30e-07 6x3b:B, 6x3b:C, 6x3b:D
54 8v4h:B 342 329 0.2420 0.2222 0.2310 1.49e-07 8v4g:A, 8v4g:B, 8v4h:A
55 6h0n:A 377 279 0.2134 0.1777 0.2401 7.00e-07 6h0n:B, 6h0p:A, 6h0p:B
56 2q1s:A 336 283 0.2452 0.2292 0.2721 1.07e-06 2pzj:A, 2q1t:A, 2q1u:A, 2q1u:B
57 6vo6:D 311 329 0.2707 0.2733 0.2584 1.31e-06 6vo6:A, 6vo6:B, 6vo6:C, 6vo8:A, 6vo8:B
58 2gn4:A 329 197 0.1656 0.1581 0.2640 1.35e-06 2gn4:B, 2gn6:A, 2gn6:B, 2gn8:A, 2gn8:B, 2gn9:A, 2gn9:B, 2gna:A, 2gna:B
59 3enk:A 340 286 0.2229 0.2059 0.2448 1.86e-06 3enk:B
60 8sk0:B 330 248 0.1847 0.1758 0.2339 1.96e-06 8shh:A, 8shh:B, 8sk0:A
61 6vlo:A 319 268 0.2197 0.2163 0.2575 2.38e-06 6vlo:B, 6vlo:C, 6vlo:D
62 1z7e:D 644 242 0.1688 0.0823 0.2190 3.43e-06 2bln:A, 2bln:B, 5j63:A, 5j63:B, 5j63:C, 5j63:D, 1z7e:A, 1z7e:B, 1z7e:C, 1z7e:E, 1z7e:F
63 4yr9:A 308 294 0.2452 0.2500 0.2619 3.95e-06 4yr9:B, 4yr9:C, 4yr9:D, 4yr9:E, 4yr9:F
64 8gjh:A 639 149 0.1178 0.0579 0.2483 7.54e-06 8gjh:B, 8gjh:C, 8gjh:D, 8gjh:E, 8gjh:F
65 6jyg:D 307 316 0.2006 0.2052 0.1994 1.80e-05 6jyg:A, 6jyg:B, 6jyg:C, 6jyg:E, 6jyg:F
66 4m55:E 164 122 0.1242 0.2378 0.3197 5.06e-05
67 8gjb:A 320 332 0.2516 0.2469 0.2380 1.46e-04 8gjb:B
68 7us5:A 346 279 0.2357 0.2139 0.2652 4.75e-04 7us5:B, 7us5:C, 7us5:D
69 7yst:A 312 268 0.2197 0.2212 0.2575 0.001 7ys8:A, 7ys8:B, 7ys9:A, 7ys9:B, 7ysa:A, 7ysa:B, 7ysm:A, 7ysm:B, 7yst:B, 7ysy:A, 7ysy:B, 7yt0:A, 7yt0:B
70 4j2o:C 316 189 0.1624 0.1614 0.2698 0.002 4j2o:A, 4j2o:B, 4j2o:D, 4j2o:E, 4j2o:F
71 2q1w:A 300 242 0.1943 0.2033 0.2521 0.003 2q1w:B, 2q1w:C
72 6bwc:C 327 201 0.1433 0.1376 0.2239 0.004 6bwc:A, 6bwc:B, 6bwc:D, 6bwc:E, 6bwc:F
73 3m2p:B 255 154 0.1146 0.1412 0.2338 0.006
74 4tqg:A 297 187 0.1306 0.1380 0.2193 0.020
75 5msu:B 459 147 0.1242 0.0850 0.2653 0.036 5mso:A, 5msu:C, 5msu:A
76 3slk:A 747 152 0.1178 0.0495 0.2434 0.085 3slk:B
77 2ydx:A 312 194 0.1561 0.1571 0.2526 0.096 2ydx:C, 2ydx:B, 2ydx:D, 2ydx:E
78 2ggs:A 273 163 0.1306 0.1502 0.2515 0.12 2ggs:B
79 1bdb:A 267 154 0.1274 0.1498 0.2597 0.19
80 4bmv:C 258 155 0.1178 0.1434 0.2387 0.20 4bmv:A, 4bmv:B, 4bmv:D, 4bmv:E, 4bmv:F, 4bmv:G, 4bmv:H, 4bmv:I, 4bmv:J
81 6vtj:A 472 126 0.0955 0.0636 0.2381 0.23
82 8der:L 105 43 0.0478 0.1429 0.3488 0.24
83 6uh2:B 255 79 0.0732 0.0902 0.2911 0.31 6uh2:A
84 5msr:B 520 149 0.1369 0.0827 0.2886 0.31 5msp:A, 5msr:A, 5msr:C, 5msr:D, 5msv:A, 5msv:B, 5msv:C, 5msv:D
85 3c1t:B 326 133 0.0987 0.0951 0.2331 0.69 3bxx:A, 3bxx:B, 3bxx:C, 3bxx:D, 3bxx:E, 3bxx:F, 3c1t:A, 3c1t:C, 3c1t:D, 2c29:D, 2c29:F, 2iod:A, 2iod:B, 2iod:C, 2iod:D, 2nnl:D, 2nnl:F
86 1mqq:A 675 155 0.1306 0.0607 0.2645 0.78 1k9e:A, 1k9f:A, 1l8n:A
87 8fem:A 327 131 0.1051 0.1009 0.2519 0.82 8fen:A
88 3w1v:A 347 266 0.1847 0.1671 0.2180 0.96 4g5h:A, 3vvc:A, 3w1v:B
89 3ndr:A 247 74 0.0732 0.0931 0.3108 1.2 3ndr:B, 3ndr:C, 3ndr:D, 3nug:A, 3nug:B, 3nug:C, 3nug:D, 3rwb:A, 3rwb:B, 3rwb:C, 3rwb:D
90 3zv5:A 275 154 0.1242 0.1418 0.2532 1.5 2y99:A, 2y99:B, 3zv5:B, 3zv6:A, 3zv6:B
91 4qqr:A 274 82 0.0637 0.0730 0.2439 1.9 4qqr:B
92 3b1f:A 286 33 0.0414 0.0455 0.3939 2.0
93 7d9f:A 591 36 0.0350 0.0186 0.3056 2.3 7d9f:B, 7d9g:A, 7d9g:B, 7d9h:A, 7d9h:B, 7d9i:A, 7d9i:B, 7d9j:A, 7d9j:B
94 5wjs:A 258 38 0.0414 0.0504 0.3421 2.7 5wjs:B
95 5amv:A 399 76 0.0796 0.0627 0.3289 2.7 1bn8:A, 2bsp:A, 3krg:A, 2nzm:A, 2o04:A, 2o0v:A, 2o0w:A, 2o17:A, 2o1d:A, 5x2i:A
96 8wg4:A 688 41 0.0446 0.0203 0.3415 3.6
97 5t5q:C 245 65 0.0573 0.0735 0.2769 4.0 5t5q:A, 5t5q:B, 5t5q:D
98 2ct5:A 73 28 0.0382 0.1644 0.4286 5.5
99 4g9p:A 405 61 0.0669 0.0519 0.3443 5.6 4s23:A, 4s23:B, 4s38:A, 4s39:A, 4s3a:A, 4s3b:A, 4s3c:A, 4s3d:A, 4s3e:A, 4s3f:A, 2y0f:A, 2y0f:B, 2y0f:C, 2y0f:D
100 4yrb:C 249 149 0.1242 0.1566 0.2617 6.4 4yrb:A, 4yrb:D, 4yrb:E
101 3tm9:A 146 43 0.0446 0.0959 0.3256 7.2 3tld:A, 3tld:B, 3tm3:A, 1vhb:A, 1vhb:B, 2vhb:A, 2vhb:B, 3vhb:A, 3vhb:B, 4vhb:A, 4vhb:B
102 4u7w:B 394 101 0.0796 0.0635 0.2475 8.4 4u7w:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218