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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRVLITGCGSRGDTEPLVALAARLRELGADARMCLPPDYVERCAEVGVPMVPVGRAVRAGAREPGELPPGAAEVVTEVVA
EWFDKVPAAIEGCDAVVTTGLLPAAVAVRSMAEKLGIPYRYTVLSPDHLPSEQSQAERDMYNQGADRLFGDAVNSHRASI
GLPPVEHLYDYGYTDQPWLAADPVLSPLRPTDLGTVQTGAWILPDERPLSAELEAFLAAGSTPVYVGFGSSSRPATADAA
KMAIKAVRASGRRIVLSRGWADLVLPDDGADCFVVGEVNLQELFGRVAAAIHHDSAGTTLLAMRAGIPQIVVRRVAYHAD
RVAELGVGVAVDGPVPTIDSLSAALDTALAPEIRARATTVADTIRADGTTVAAQLLFDAVSLEK

The query sequence (length=384) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1pn3:A 391 391 1.0000 0.9821 0.9821 0.0 1pn3:B, 1pnv:B, 1pnv:A
2 3h4i:A 392 385 0.8464 0.8291 0.8442 0.0 3h4t:A
3 1rrv:A 401 388 0.5547 0.5312 0.5490 2.90e-124 1rrv:B
4 5gl5:A 431 419 0.2682 0.2390 0.2458 2.38e-15 5gl5:B
5 6kqx:A 327 131 0.0964 0.1131 0.2824 2.21e-05
6 7vlb:A 385 110 0.0885 0.0883 0.3091 2.74e-04
7 7vlb:B 353 110 0.0885 0.0963 0.3091 2.88e-04
8 3wag:B 401 101 0.0885 0.0848 0.3366 0.002 3wad:A, 3wag:A
9 3wag:B 401 55 0.0495 0.0474 0.3455 0.16 3wad:A, 3wag:A
10 8sft:B 428 211 0.1328 0.1192 0.2417 0.039 8gkn:A, 8gkn:B, 8sft:A, 8sft:C, 8sft:D, 8sfu:A, 8sfu:B, 8sfw:A, 8sfy:A
11 4rif:B 379 48 0.0417 0.0422 0.3333 0.33 4rif:A, 4rih:A, 4rih:B, 4rii:B
12 4rii:A 354 48 0.0417 0.0452 0.3333 0.36
13 3oti:A 379 76 0.0677 0.0686 0.3421 0.36 3oti:B
14 4lei:A 375 73 0.0625 0.0640 0.3288 0.55 4lei:B
15 1gk0:B 522 75 0.0547 0.0402 0.2800 0.68 2adv:C, 1gk0:D, 1gk1:B, 1gk1:D, 1jvz:B, 1jw0:B
16 4nhe:B 326 92 0.0651 0.0767 0.2717 1.3 4nhe:A, 4nhe:C
17 3oth:A 395 28 0.0339 0.0329 0.4643 3.0 3otg:A, 3oth:B
18 7xh4:A 177 32 0.0365 0.0791 0.4375 3.2 7xh2:A
19 4g2t:A 356 59 0.0495 0.0534 0.3220 3.3
20 2ffl:A 732 83 0.0651 0.0342 0.3012 4.9 2ffl:B, 2ffl:C, 2ffl:D, 2qvw:A, 2qvw:B, 2qvw:C, 2qvw:D
21 6y79:X 167 50 0.0443 0.1018 0.3400 6.3 7zkp:X
22 3p2h:A 184 51 0.0521 0.1087 0.3922 6.5
23 7ane:s 165 33 0.0312 0.0727 0.3636 8.4 7aor:s, 6hiv:Ci, 6hiw:Ci, 6hiz:Ci, 7pua:Ci, 7pub:Ci, 6sg9:Ci, 6sgb:Ci
24 2ayi:A 397 69 0.0729 0.0705 0.4058 8.7 2ayi:B, 2ayi:C, 2ayi:D, 2ayi:E
25 7wca:B 679 66 0.0599 0.0339 0.3485 9.7 4aue:A, 4aue:B, 4aue:C, 4aue:D, 4aul:A, 4aul:B, 4aul:C, 4aul:D, 4aum:A, 4aum:B, 4aum:C, 4aum:D, 4aun:A, 4aun:B, 4aun:C, 4aun:D, 4aun:E, 4aun:F, 4aun:G, 4aun:H, 4b2y:A, 4b2y:B, 4b2y:C, 4b2y:D, 4b31:A, 4b31:B, 4b31:C, 4b31:D, 4b40:A, 4b40:B, 4b40:C, 4b40:D, 4b5k:A, 4b5k:B, 4b5k:C, 4b5k:D, 4b7a:A, 4b7a:B, 4b7a:C, 4b7a:D, 7vn0:A, 7vn0:B, 7vn0:C, 7vn0:D, 7wca:A, 7wca:C, 7wca:D, 5xvz:A, 5xvz:B, 5xvz:C, 5xvz:D, 5xy4:A, 5xy4:B, 5xy4:C, 5xy4:D, 5xzm:A, 5xzm:B, 5xzm:C, 5xzm:D, 5xzn:A, 5xzn:B, 5xzn:C, 5xzn:D, 5y17:A, 5y17:B, 5y17:C, 5y17:D, 5yem:A, 5yem:B, 5yem:C, 5yem:D, 5zz1:A, 5zz1:B, 5zz1:D, 5zz1:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218