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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRNLKLFRTLEFRDIQGPGNPQCFSLRTEQGTVLIGSEHGLIEVDPVSREVKNEVSLVAEGFLPEDGSGRIVGVQDLLDQ
ESVCVATASGDVILCSLSTQQLECVGSVASGISVMSWSPDQELVLLATGQQTLIMMTKDFEPILEQQIHQDDFGESKFIT
VESALPWDDHRPQVTWRGDGQFFAVSVVCPETGARKVRVWNREFALQSTSEPVAGLGPALAWKPSGSLIASTQDKPNQQD
IVFFEKNGLLHGHFTLPFLKDEVKVNDLLWNADSSVLAVWLEDLQKTCVQLWTVGNYHWYLKQSLSFSTCGKSKIVSLMW
DPVTPYRLHVLCQGWHYLAYDWHWTTDRSVGDNSSDLSNVAVIDGNRVLVTVFRQTVVPPPMCTYQLLFPHPVNQVTFLA
HPQKSNDLAVLDASNQISVYKCGDCPSADPTVKLGAVGGSGFKVCLRTPHLEKRYKIQFPLKLGLLTWIEEDVFLAVSHS
EFSPRSVIHHLTAASSEMDEEHGQLNVSSSAAVDGVIISLCCNSKTKSVVLQLADGQIFKYLWESPSLAIKPWKNSGGFP
VRFPYPCTQTELAMIGEEECVLGLTDRCRFFINDIEVASNITSFAVYDEFLLLTTHSHTCQCFCLRDASFKTLQAGLSSN
HVSHGEVLRKVERGSRIVTVVPQDTKLVLQMPRGNLEVVHHRALVLAQIRKWLDKLMFKEAFECMRKLRINLNLIYDHNP
KVFLGNVETFIKQIDSVNHINLFFTELKEEDVTKTMYPAPVGNKIDLVCDAMRAVMESINPHKYCLSILTSHVKKTTPEL
EIVLQKVHELQGNADAVSAEEALKYLLHLVDVNELYDHSLGTYDFDLVLMVAEKSQKDPKEYLPFLNTLKKMETNYQRFT
IDKYLKRYEKAIGHLSKCGPEYFPECLNLIKDKNLYNEALKLYSPSSQQYQDISIAYGEHLMQEHMYEPAGLMFARCGAH
EKALSAFLTCGNWKQALCVAAQLNFTKDQLVGLGRTLAGKLVEQRKHIDAAMVLEECAQDYEEAVLLLLEGAAWEEALRL
VYKYNRLDIIETNVKPSILEAQKNYMAFLDSQTATFSRHKKRLLVVEALSEVVQNTENLKDEVYHILKVLFLFEFDEQGR
ELQKAFEDTLQLMERSLPEIWPPKINRRTQWKLSLLD

The query sequence (length=1157) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8pu0:A 1157 1157 1.0000 1.0000 1.0000 0.0
2 8ptx:A 1215 1215 1.0000 0.9523 0.9523 0.0
3 8asw:A 1255 1067 0.2809 0.2590 0.3046 7.58e-125
4 8hmc:B 1195 90 0.0199 0.0192 0.2556 0.055 8hmd:B
5 8fgw:C 1342 91 0.0242 0.0209 0.3077 1.0 8fh3:C
6 8fgw:A 1081 87 0.0225 0.0241 0.2989 3.1
7 1t6c:A 306 57 0.0164 0.0621 0.3333 4.1 2j4r:A
8 5m60:A 755 126 0.0242 0.0371 0.2222 4.9
9 8cja:B 731 33 0.0121 0.0192 0.4242 6.0 8cjb:B, 8cjc:B, 8cmw:B, 7nyp:A, 7nyp:B, 7nys:A, 7nys:B, 7nz5:A, 7nz5:B, 7o0d:A, 1ru3:A, 7zkj:B, 7zkk:B, 7zkv:B
10 8z9x:B 567 110 0.0190 0.0388 0.2000 6.1 8z9x:A
11 7quy:A 352 44 0.0138 0.0455 0.3636 6.5 7qul:A, 7quy:B, 7quy:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218