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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRNKIFISHATPDDNDFTRWLALKLIGLGYEVWCDILFLDKGVDFWSNIEKVIREDTCKFLLVSSSYSNQREGVLKELAV
AAKVKKQLKDDKFIIPLAIDEQLSYDDINIDIVRLNAIDFKMSWARGLKDILEAFEKQKVPKEVADASKSNLLYQQIFLH
DKSVIEKEEIYDSNWLSILSFPEELRFHEYNWMLPKRFDVRELTFPAVRYKNYLCTFAWAYDFTYHLPKTETYHKSKTIR
IPTEEILSGSYDSNFIRNAECKRLIVQLLNKAFELRMKDKEVQEYEMSNKTAYWLEKGKLEKDKFEKTMLVGKQKDKNWH
FAISGASKLYPFPVLMISSHIFFTADGKKLIDSSSVQHSSRRRQGKNWWNNTWRTKLLAFIKYLSDDDTSFYLEMGSEEK
VFVSNEPVKFKGNVSYNI

The query sequence (length=418) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ffi:A 419 417 0.9976 0.9952 1.0000 0.0 8ffi:E, 8ffi:I, 8ffi:M, 8i87:G, 8i87:O, 8i87:A, 8i87:C, 8j7s:B, 8j7s:F, 8j7s:J, 8j7s:N, 8jr8:B, 8jr8:D, 8oz6:A, 8oz6:C, 8oz6:E, 8oz6:G, 8ozd:A, 8ozd:C, 8oze:E, 8oze:G, 8ozf:A, 8ozf:C, 8ozf:F, 8ozf:H, 8ozg:A, 8ozg:C, 8ozg:F, 8ozg:H, 8ozi:A, 8ozi:C, 8ozi:E, 8ozi:G, 8sp0:A, 8sp0:E, 8sp3:A, 8sp3:E, 8spo:A
2 8spo:M 394 417 0.9378 0.9949 0.9400 0.0 8spo:E
3 8squ:A 372 417 0.8852 0.9946 0.8873 0.0
4 8spo:I 371 417 0.8828 0.9946 0.8849 0.0
5 8isz:B 450 416 0.7488 0.6956 0.7524 0.0 8ifk:A, 8ifl:A, 8ifl:F, 8ifl:J, 8ifl:N, 8ifm:A, 8ifm:F, 8ifm:J, 8ifm:N, 8it0:B, 8it0:F, 8it1:J, 8it1:N, 8it1:B, 8it1:F, 8j8h:B, 8j9g:B, 8j9p:B, 8j9p:D, 8jay:B, 8jay:D, 8jay:J, 8jay:N, 8k9g:B, 8k9g:F, 8u72:B, 8u72:D, 8u72:H, 8u72:F, 8u7b:B
6 8qlp:E 419 417 0.7416 0.7399 0.7434 0.0 8qlp:A, 8qlp:I, 8qlp:M
7 7uxu:A 134 93 0.0670 0.2090 0.3011 0.002 7uxu:B, 7uxu:C, 7uxu:D
8 4een:A 229 116 0.0598 0.1092 0.2155 1.2
9 5lzw:ii 372 73 0.0550 0.0618 0.3151 2.6 5lzx:ii, 5lzy:ii, 5lzz:ii
10 7uy7:A 552 126 0.0742 0.0562 0.2460 2.9
11 7uy5:I 528 126 0.0742 0.0587 0.2460 3.3
12 4wwj:A 256 92 0.0574 0.0938 0.2609 3.3 6p5q:A, 6p5q:B, 4wwj:B, 4wwz:A, 4wwz:B, 4wx0:A, 4wx0:B
13 5u0l:A 488 70 0.0478 0.0410 0.2857 4.5 5u0m:A, 5u0m:B
14 3ju8:A 486 47 0.0335 0.0288 0.2979 5.8 3ju8:B
15 2vp1:A 313 39 0.0287 0.0383 0.3077 8.7 2vp1:B
16 7tu2:A 434 46 0.0335 0.0323 0.3043 9.1 7tu0:A, 7tu0:B, 7tu0:C, 7tu2:B, 7tu2:C, 7tu3:A, 7tu3:B, 7tu3:C, 7tu4:A, 7tu4:B, 7tu4:C, 7tu5:A, 7tu5:B, 7tu5:C, 7tu5:D, 7tu5:E, 7tu5:F, 7tu6:A, 7tu6:B, 7tu6:C, 7tu6:D, 7tu6:E, 7tu6:F, 7tu7:A, 7tu7:B, 7tu7:C, 7tu7:D, 7tu7:E, 7tu7:F, 7tu8:A, 7tu8:B, 7tu8:C, 7tu8:D, 7tu8:E, 7tu8:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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