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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRLSYEALEWRTPIENSTEPVSLPPPPPFFGQERAREALELAIRGGFHAYLVGPPSLGKHEALLAYLSTQSVETPPDLLY
VPLSERKVAVLTLPSGQEIHLAEAVEGLLLEVNRLDELFRQGSFLREKTQLEARFKEAREQQLEALRREAQEAGFALSTN
GERLELTGPGPVPAELSARLEEVTLGSLAASAELEVALRRLRRDWALHYLNNRFEPLFQRFPQARAYLEALRARLARYAE
TGEPLDPAQWRPNLLTSSSSGTPPPIVYEPYATAPRLFGRLDYLVDRGVWSTNVSLIRPGAVHRAQGGYLILDALSLKRE
GTWEAFKRALRNGQVEPVTEPQAPAGLEVEPFPIQMQVILVGTPEAFEGLEEDPAFSELFRIRAEFSPTLPASPENCTAL
GGWLLAQGFQLTQGGLTRLYDEARRMAEQRDRMDARLVEIRALAEEAAVLGGGLLTAESVEQAIAAREHRSFLSEEEFLR
AVQEGVIRLRTTGRAVGEVNSLVVVEAAPYWGRPARLTARAAPGRDHLISIDREAGLGGQIFHKAVLTLAGYLRSRYIEH
GSLPVTISLAFEQNYVSIEGDAAGLAELVAALSAIGNLPLRQDLAVTGAVDQTGKVLAVGAINAKVEGFFRVCKALGLSG
TQGVILPEANLANLTLRAEVLEAVRAGQFHIYAVETAEQALEILAGARMEGFRGLQEKIRAGLEAFARLEEGHDKEDRE

The query sequence (length=719) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8k8y:A 719 719 0.9986 0.9986 0.9986 0.0 8k8y:G, 8k8y:F, 8k8y:E, 8k8y:D, 8k8y:C, 8k8y:B, 8k8z:A, 8k8z:F, 8k8z:E, 8k8z:D, 8k8z:C, 8k8z:B, 8k90:B, 8k90:C, 8k90:D, 8k91:A, 8k91:B, 8k91:C, 8k91:D, 8k91:E, 8k91:F, 8k91:G, 8k92:A, 8k92:F, 8k92:E, 8k92:D, 8k92:C, 8k92:B, 8k93:B, 8k93:C, 8k93:D, 8k93:E, 8k94:B, 8k94:C, 8k94:D, 8k95:A, 8k95:B, 8k95:C, 8k95:D, 8k95:E, 8k96:B, 8k96:A, 8k96:G, 8k96:F, 8k96:E, 8k96:D, 8k96:C, 8k97:A, 8k97:F, 8k97:E, 8k97:D, 8k97:C, 8k97:B
2 7ev6:A 594 521 0.6843 0.8283 0.9443 0.0 7eux:A, 7euy:A, 7ev4:A, 4fwd:A, 4fwg:A, 4fwh:A
3 7ev6:A 594 109 0.1502 0.1818 0.9908 1.17e-54 7eux:A, 7euy:A, 7ev4:A, 4fwd:A, 4fwg:A, 4fwh:A
4 3k1j:A 566 471 0.1655 0.2102 0.2527 1.80e-20 3k1j:B
5 3k1j:A 566 89 0.0362 0.0459 0.2921 2.6 3k1j:B
6 1z0b:A 203 193 0.0709 0.2512 0.2642 8.48e-10
7 7fd4:D 779 153 0.0598 0.0552 0.2810 2.42e-05 7fd4:B, 7fd4:C, 7fd4:E, 7fd4:F, 7fd4:A, 7fd5:B, 7fd5:C, 7fd5:E, 7fd5:A, 7fd5:F, 7fd5:D, 7fid:D, 7fid:A, 7fid:B, 7fid:C, 7fid:E, 7fid:F, 7fie:B, 7fie:C, 7fie:D, 7fie:E, 7fie:A, 7fie:F, 7fiz:B, 7fiz:C, 7fiz:E, 7fiz:A, 7fiz:D, 7fiz:F, 8k3y:B, 8k3y:C, 8k3y:D, 8k3y:E, 6wqh:A, 6wqh:B, 6wqh:C, 6wqh:F, 6wqh:D, 6wqh:E, 4ypl:A, 4ypl:B, 4ypl:C, 4ypl:F, 4ypl:D, 4ypl:E, 4ypm:A, 7yph:B, 7yph:D, 7ypi:A, 7ypi:B, 7ypj:A, 7ypj:B, 7ypj:C, 7ypj:D, 7ypk:F, 7ypk:B, 7ypk:E, 7ypk:A, 7ypk:C, 7ypk:D, 7yuv:A, 7yuv:B, 7yuv:C, 7yuw:A, 7yuw:B, 7yuw:C, 7yuw:D, 7yux:A, 7yux:C, 7yux:E, 7yux:D, 7yux:B
8 7p6u:A 772 183 0.0695 0.0648 0.2732 7.27e-05 7p6u:B, 7p6u:C, 7p6u:D, 7p6u:E
9 7p09:F 520 72 0.0376 0.0519 0.3750 5.39e-04 7ksl:C, 7ksl:E, 7p0m:F
10 8ojl:A 777 72 0.0376 0.0347 0.3750 5.52e-04 9cc0:A, 9cc0:C, 9cc0:E, 9cc0:B, 9cc0:D, 9cc0:F, 9cc3:B, 9cc3:C, 9cc3:D, 9cc3:E, 7krz:A, 7krz:C, 7krz:B, 7krz:D, 7krz:E, 7krz:F, 7ksl:B, 7ksl:A, 7ksl:F, 7ksm:B, 7ksm:A, 7ksm:C, 7ksm:D, 7ksm:E, 7ksm:F, 7nfy:A, 7nfy:B, 7nfy:C, 7nfy:E, 7nfy:D, 7nfy:F, 7ng4:B, 7ng4:C, 7ng4:D, 7ng4:A, 7ng4:E, 7ng4:F, 7ng5:A, 7ng5:D, 7ng5:B, 7ng5:C, 7ng5:E, 7ng5:F, 7ngc:A, 7ngc:B, 7ngc:C, 7ngc:D, 7ngc:E, 7ngc:F, 7ngf:A, 7ngf:F, 7ngf:B, 7ngf:C, 7ngf:D, 7ngf:E, 7ngl:A, 7ngl:B, 7ngl:C, 7ngl:D, 7ngl:E, 7ngl:F, 7ngp:A, 7ngp:B, 7ngp:C, 7ngp:D, 7ngp:E, 7ngp:F, 7ngq:A, 7ngq:B, 7ngq:C, 7ngq:D, 7ngq:E, 7ngq:F, 8ojl:B, 8ojl:C, 8ojl:D, 8ojl:E, 8ojl:F, 8oka:A, 8oka:B, 8oka:C, 8oka:D, 8oka:E, 8oka:F, 8om7:A, 8om7:B, 8om7:C, 8om7:D, 8om7:E, 8om7:F, 8ovf:A, 8ovf:B, 8ovf:C, 8ovf:D, 8ovf:E, 8ovf:F, 7oxo:A, 7oxo:B, 7oxo:C, 7oxo:D, 7oxo:E, 7oxo:F, 7p09:A, 7p09:B, 7p09:D, 7p09:C, 7p09:E, 7p0b:A, 7p0b:B, 7p0b:C, 7p0b:D, 7p0b:E, 7p0b:F, 7p0m:A, 7p0m:B, 7p0m:C, 7p0m:D, 7p0m:E, 6wzv:A, 6wzv:B, 6x1m:A, 6x1m:B, 6x27:A, 6x27:B, 6x27:C, 6x27:D, 6x27:E, 6x27:F, 6x27:G, 6x27:H, 6x27:I, 6x27:J, 6x27:K, 6x27:L
11 8dvh:A 196 116 0.0473 0.1735 0.2931 6.24e-04 8dvh:B
12 3m6a:A 496 168 0.0612 0.0887 0.2619 0.007 3m6a:B, 3m6a:C, 3m6a:D, 3m6a:E, 3m6a:F
13 6v11:E 464 213 0.0737 0.1142 0.2488 0.011
14 6on2:B 524 105 0.0417 0.0573 0.2857 0.012 6on2:C, 6on2:A, 6on2:D, 6on2:E, 6on2:F
15 6v11:C 503 105 0.0417 0.0596 0.2857 0.012 6v11:A, 6v11:B, 6v11:F
16 5ksz:A 398 205 0.0709 0.1281 0.2488 0.087 5kso:A, 5ksp:A, 5ksp:B, 5ksy:A, 5kty:A, 5ku1:A
17 5eqt:A 249 54 0.0278 0.0803 0.3704 0.11
18 7sxo:F 549 99 0.0389 0.0510 0.2828 0.31 7sxo:A, 7sxo:E, 7sxo:B, 7sxo:C, 7sxo:D
19 1in5:A 301 98 0.0487 0.1163 0.3571 1.6 1in4:A, 1in6:A, 1in7:A, 1in8:A, 1j7k:A
20 1v2a:B 209 59 0.0320 0.1100 0.3898 1.7 1v2a:A, 1v2a:C, 1v2a:D
21 7qw6:A 556 135 0.0445 0.0576 0.2370 2.7 7qw5:A, 7qw7:A
22 2bc0:A 473 33 0.0153 0.0233 0.3333 5.6 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
23 5n5s:B 481 85 0.0376 0.0561 0.3176 5.8 5n5s:A, 5n5s:C, 5n5s:D
24 5fn1:A 217 75 0.0278 0.0922 0.2667 5.9
25 5lie:B 397 175 0.0682 0.1234 0.2800 6.5 5li8:A, 5lie:A
26 2d62:A 375 74 0.0306 0.0587 0.2973 6.6
27 3ngl:A 275 102 0.0264 0.0691 0.1863 7.0 3ngl:C
28 6s8f:F 2571 70 0.0250 0.0070 0.2571 7.7 7mq8:NR, 7mq9:NR, 7mqa:NR, 6s8f:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218