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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRIEKCYFCSGPIYPGHGMMFVRNDCKVFRFCKSKCHKNFKKKRNPRKVRWTKAFRKAAGKELTVDNSFEFEKRRNEPIK
YQRELWNKTIDAMKRVEEIKQKRQAKFIMNRLKKNKELQKVQDIKEVKQNIHLIRAPLA

The query sequence (length=139) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8fl2:SV 139 139 1.0000 1.0000 1.0000 1.01e-100 8fkp:SV, 8fkq:SV, 8fkr:SV, 8fks:SV, 8fkt:SV, 8fku:SV, 8fkv:SV, 8fkw:SV, 8fkx:SV, 8fky:SV, 8fkz:SV, 8fl0:SV, 8fl3:SV, 8fl4:SV, 8fl6:SV, 8fl7:SV, 8fl9:SV, 8fla:SV, 8flb:SV, 8flc:SV, 8fld:SV, 8fle:SV, 8flf:SV, 8idt:7, 8idy:7, 8ie3:7, 8ine:7, 8inf:7, 8ink:7, 8ipd:7, 8ipx:7, 8ipy:7, 8ir1:7, 8ir3:7, 6lss:7, 6lu8:7
2 8hfr:tB 154 135 0.5899 0.5325 0.6074 3.75e-58 7bt6:u, 7btb:u, 6c0f:u, 6elz:u, 6em1:u, 6ft6:u, 3jct:u, 6m62:u, 6n8j:u, 6n8k:u, 6n8l:u, 7nac:u, 7naf:u, 7of1:u, 7oh3:u, 7ohq:u, 7ohr:u, 7ohs:u, 7ohu:u, 7ohv:u, 7ohy:u, 7r7a:u, 7u0h:u, 7ug6:u, 7uoo:u, 7uqb:u, 7uqz:u, 7v08:u, 8v83:u, 8v84:u, 8v87:u, 6ylg:u, 6ylh:u, 6ylx:u, 6yly:u, 7z34:u
3 8pv1:CQ 183 134 0.5036 0.3825 0.5224 1.58e-49 8i9r:CQ, 8i9t:CQ, 8i9v:CQ, 8i9w:CQ, 8i9x:CQ, 8i9y:CQ, 8i9z:CQ, 8ia0:CQ, 8pv2:CQ, 8pv3:CQ, 8pv4:CQ, 8pv5:CQ, 8pv6:CQ, 8pv7:CQ, 8pv8:CQ, 8pvk:CQ, 8pvl:CQ
4 8esq:u 114 113 0.4964 0.6053 0.6106 3.22e-49 8etc:u, 8eth:u, 8eti:u, 8etj:u, 8eug:u, 8eui:u
5 7ohx:u 100 112 0.4892 0.6800 0.6071 4.54e-45 7oht:u
6 8esr:u 101 112 0.4820 0.6634 0.5982 7.42e-45
7 8br8:LX 63 62 0.3022 0.6667 0.6774 1.51e-26 8brm:LX, 8bsi:LX, 8bsj:LX, 8btd:LX, 8btr:LX
8 5dat:n4 135 100 0.2734 0.2815 0.3800 4.04e-18 8aaf:J, 8agt:J, 8agu:J, 8agv:J, 8agw:J, 8agx:J, 8agz:J, 5apn:W, 5apo:W, 7azy:f, 7b7d:LS, 8bip:LW, 8bjq:LW, 8bn3:N4, 8bqd:AE, 8bqx:AE, 8ccs:I, 8cdl:I, 8cdr:I, 8ceh:I, 8cf5:I, 8cg8:I, 8cgn:I, 8civ:I, 8cku:I, 8cmj:I, 5dat:N4, 5dc3:N4, 5dc3:n4, 5dge:N4, 5dge:n4, 5dgf:N4, 5dgf:n4, 5dgv:N4, 5dgv:n4, 8eub:AW, 8evp:AW, 8evq:AW, 8evr:AW, 8evs:AW, 8evt:AW, 8ewb:AW, 8ewc:AW, 5fci:N4, 5fci:n4, 5fcj:N4, 5fcj:n4, 5gak:Y, 6gq1:W, 6gqb:W, 6gqv:W, 5h4p:W, 6hd7:Y, 6hhq:7, 6hhq:CY, 5i4l:N4, 5i4l:n4, 6i7o:AE, 6i7o:XE, 5it7:WW, 3j6x:64, 3j6y:64, 3j77:74, 3j78:74, 5juo:BA, 5jup:BA, 5jus:BA, 5jut:BA, 5juu:BA, 8k2d:LW, 8k82:LW, 5lyb:N4, 5lyb:n4, 5m1j:W5, 5mc6:AE, 5mei:7, 5mei:CY, 7mpi:AW, 7mpj:AW, 6n8m:j, 6n8n:j, 6n8o:j, 7n8b:AW, 5ndg:N4, 5ndv:N4, 5ndv:n4, 5ndw:N4, 5ndw:n4, 7nrc:LY, 7nrd:LY, 5obm:N4, 5obm:n4, 6oig:W, 5on6:7, 5on6:CY, 7osa:eL24, 7osm:eL24, 8p8m:QW, 8p8n:QW, 8p8u:QW, 8pfr:QW, 6q8y:AE, 6qik:v, 6qt0:v, 6qtz:v, 6r84:Y, 6r86:Y, 6r87:Y, 6ri5:v, 7rr5:LW, 6rzz:v, 6s05:v, 6s47:AY, 6snt:at, 6sv4:AE, 6sv4:XE, 6sv4:zE, 6t4q:LW, 5t62:j, 5t6r:j, 6t7i:LW, 6t7t:LW, 6t83:Wy, 6t83:H, 5tbw:7, 5tbw:CY, 6tb3:AE, 5tga:N4, 5tga:n4, 5tgm:N4, 5tgm:n4, 6tnu:AE, 7too:AL24, 7top:AL24, 4u3m:N4, 4u3m:n4, 4u3n:N4, 4u3n:n4, 4u3u:N4, 4u3u:n4, 4u4n:N4, 4u4n:n4, 4u4o:N4, 4u4o:n4, 4u4q:N4, 4u4q:n4, 4u4r:N4, 4u4r:n4, 4u4u:N4, 4u4u:n4, 4u4y:N4, 4u4y:n4, 4u4z:N4, 4u4z:n4, 4u50:N4, 4u50:n4, 4u51:N4, 4u51:n4, 4u52:N4, 4u52:n4, 4u53:N4, 4u53:n4, 4u55:N4, 4u55:n4, 4u56:N4, 4u56:n4, 4u6f:N4, 4u6f:n4, 6uz7:AW, 4v4b:BS, 4v6i:BZ, 4v7h:BS, 4v7r:BV, 4v7r:DV, 4v88:BW, 4v88:DW, 4v8t:W, 4v8y:BW, 4v8z:BW, 4v91:W, 6woo:W, 6xiq:W, 6xir:W, 8y0u:LW, 6z6j:LW, 6z6k:LW, 7zpq:BV, 7zrs:BV, 7zs5:BX, 7zuw:BV, 7zux:EV, 7zw0:LZ
9 8ifd:2Q 124 91 0.2518 0.2823 0.3846 2.60e-16 7a01:l2, 8a3d:Q, 5aj0:AW, 8b5l:W, 8b6c:W, 9bdl:AL24, 9bdn:AL24, 9bdp:AL24, 8bpo:V2, 8btk:BW, 7cpu:LW, 7cpv:LW, 4d5y:W, 4d67:W, 9f1b:BW, 9f1c:BW, 9f1d:BW, 7f5s:LW, 6frk:W, 6ftg:W, 6fti:W, 6ftj:W, 8g5y:LW, 8g5z:LW, 8g60:LW, 8g61:LW, 8g6j:LW, 8glp:LW, 6gz3:AW, 6gz4:AW, 6gz5:AW, 8ife:2Q, 6ip5:2Q, 6ip6:2Q, 6ip8:2Q, 3j7o:W, 3j7p:W, 3j7q:W, 3j7r:W, 3j92:W, 3jag:W, 3jah:W, 3jai:W, 3jaj:W, 3jan:W, 8jdj:b, 8jdk:b, 8jdl:b, 8jdm:b, 8k2c:LW, 5lks:LW, 6lqm:f, 6lsr:f, 7ls1:Q2, 7mdz:W, 7nfx:W, 7nwg:W, 7nwi:W, 7o7y:BW, 7o7z:BW, 7o80:BW, 7o81:BW, 7obr:W, 8ohd:LW, 8oj0:LW, 8oj5:LW, 8oj8:LW, 6ole:X, 6olf:X, 6olg:AW, 6oli:X, 6olz:AW, 6om0:X, 6om7:X, 7ow7:u, 7oya:W1, 7oyb:W1, 7oyc:W1, 7oyd:W, 8p2k:BW, 6p5i:AW, 6p5j:AW, 6p5k:AW, 6p5n:AW, 8q7z:BW, 8q87:BW, 8qfd:W, 7qgg:X, 8qoi:LW, 7qvp:LW, 7qvp:MW, 7qwq:W, 7qwr:W, 7qws:W, 6qzp:LW, 6r6p:W, 8rjb:W, 8rjc:W, 8rjd:W, 8scb:W, 6swa:U, 5t2c:Q, 6t59:W3, 7tm3:W, 7toq:AL24, 7tor:AL24, 7tut:W, 4ug0:LW, 4ujc:BW, 4ujd:AW, 4uje:CW, 4v6x:CW, 6w6l:X, 6xa1:LW, 7xnx:LW, 7xny:LW, 8xsx:LW, 8xsy:LW, 8xsz:LW, 6y0g:LW, 8y0w:LW, 8y0x:LW, 6y2l:LW, 6y57:LW, 6y6x:LW, 8yoo:LW, 8yop:LW, 6z6l:LW, 6z6m:LW, 6z6n:LW, 6zm7:LW, 6zme:LW, 6zmi:LW, 6zmo:LW, 6zvk:l2
10 7ls2:Q2 110 57 0.1942 0.2455 0.4737 6.35e-15 8bhf:J1, 6d90:W, 6d9j:W, 6hcf:W3, 6hcm:W3, 5lzs:W, 5lzt:W, 5lzu:W, 5lzv:W, 5lzw:W, 5lzx:W, 5lzy:W, 5lzz:W, 6mtb:W, 6mtc:W, 6mtd:W, 6mte:W, 7nwh:W, 6r5q:W, 6r6g:W, 6r7q:W, 6sgc:W2, 7ucj:W, 7uck:W, 7zjw:LZ, 7zjx:LZ
11 5ndg:n4 118 57 0.2014 0.2373 0.4912 7.14e-15
12 8c3a:7 118 84 0.2374 0.2797 0.3929 1.11e-14 8c3a:BR, 8cq7:7, 8cq7:BR, 8cqw:7, 8cqw:BR, 8cre:7, 8cre:BR, 8oeq:7, 8oeq:BR, 7pzy:7, 7q08:7, 7q0f:7, 7q0p:7, 7q0r:7, 8q5i:7
13 4v4n:AV 66 57 0.1942 0.4091 0.4737 8.95e-14 6skf:BY, 6skg:BY, 6th6:BY, 4v6u:BV
14 4v6w:CW 130 90 0.2446 0.2615 0.3778 2.32e-13 6xu6:CW, 6xu7:CW, 6xu8:CW
15 7olc:LW 133 94 0.2230 0.2331 0.3298 5.92e-13 7old:LW, 8oo0:LW, 7r81:Y1, 7z3n:LW, 7z3o:LW
16 8hku:L24E 54 52 0.1799 0.4630 0.4808 1.36e-12 8hkv:L24E, 8hky:L24E, 8hkz:L24E, 8hl1:L24E, 8hl2:L24E, 8hl3:L24E, 8hl4:L24E, 8hl5:L24E
17 9bh5:CW 88 56 0.1799 0.2841 0.4464 6.90e-12 9cai:CW
18 7qiw:Y 62 57 0.1799 0.4032 0.4386 8.24e-12 7qiz:Y
19 4v3p:LZ 75 66 0.1799 0.3333 0.3788 1.75e-11 8azw:L, 8b2l:L3, 8ip8:OA, 8ipa:OA, 8ipb:OA, 8jiv:CW, 4v7e:CW
20 5an9:G 69 68 0.2014 0.4058 0.4118 2.56e-11 5anb:G, 5anc:G, 6qkl:G
21 6zj3:Lm 66 61 0.1799 0.3788 0.4098 6.11e-10
22 4v9f:U 56 55 0.1583 0.3929 0.4000 2.12e-09 3cc2:U, 3cc4:U, 3cc7:U, 3cce:U, 3ccj:U, 3ccl:U, 3ccm:U, 3ccq:U, 3ccr:U, 3ccs:U, 3ccu:U, 3ccv:U, 3cd6:U, 3cma:U, 3cme:U, 3cpw:T, 3cxc:T, 3g4s:U, 3g6e:U, 3g71:U, 3i55:U, 3i56:U, 1jj2:T, 1k73:V, 1k8a:V, 1k9m:V, 1kc8:V, 1kd1:V, 1kqs:T, 1m1k:V, 1m90:V, 1n8r:V, 1nji:V, 2otj:U, 2otl:U, 3ow2:T, 1q7y:V, 1q81:V, 1q82:V, 1q86:V, 2qa4:U, 2qex:U, 1qvf:T, 1qvg:T, 1s72:U, 4v4p:AR, 4v4r:BT, 4v4s:BT, 4v4t:BT, 1vq4:U, 1vq5:U, 1vq6:U, 1vq7:U, 1vq8:U, 1vq9:U, 1vqk:U, 1vql:U, 1vqm:U, 1vqn:U, 1vqo:U, 1vqp:U, 1w2b:T, 1yhq:U, 1yi2:U, 1yij:U, 1yit:U, 1yj9:U, 1yjn:U, 1yjw:U
23 7pwg:W 65 62 0.1727 0.3692 0.3871 8.98e-09 8fru:W, 7pwo:W2
24 5xy3:W 59 54 0.1367 0.3220 0.3519 1.49e-06
25 4v8m:BY 100 68 0.1583 0.2200 0.3235 3.52e-06 8ova:BY, 8ove:BY, 5t5h:Y
26 7nad:u 56 21 0.1295 0.3214 0.8571 4.14e-06 7r72:u
27 3j79:0 62 57 0.1367 0.3065 0.3333 4.30e-06 3jbn:A0, 3jbo:A0, 3jbp:A0, 8tpu:A0, 5umd:0
28 8rxh:LX 85 61 0.1439 0.2353 0.3279 6.21e-06 8a3w:X, 8a98:X, 6az3:X, 3jcs:X, 8ovj:X, 8rxx:LX, 5t2a:W
29 5xxb:V 63 57 0.1511 0.3333 0.3684 1.72e-05
30 6zu5:LW0 93 51 0.1295 0.1935 0.3529 1.54e-04
31 4v8p:BT 61 57 0.1439 0.3279 0.3509 0.002 4v8p:CT, 4v8p:ET, 4v8p:GT
32 7bhp:LW 42 52 0.1295 0.4286 0.3462 0.002
33 7qep:N4 89 61 0.1439 0.2247 0.3279 0.005
34 4v58:G 2060 76 0.1511 0.0102 0.2763 0.51 4v58:H, 4v58:I, 4v58:J, 4v58:K, 4v58:L, 4v59:G, 4v59:H, 4v59:I, 4v59:J, 4v59:K, 4v59:L
35 1tqh:A 242 153 0.2446 0.1405 0.2222 1.1
36 1dvp:A 217 80 0.1367 0.0876 0.2375 3.4
37 6zj9:A 220 78 0.1583 0.1000 0.2821 3.8 6zjc:B, 6zjc:A, 6zjc:D, 6zjc:C
38 6e10:1 719 48 0.1151 0.0223 0.3333 4.4 6e10:2, 6e10:3, 6e10:4, 6e10:5, 6e10:6, 6e11:1, 6e11:3, 6e11:2, 6e11:4, 6e11:5, 6e11:6
39 2qb6:A 393 36 0.0863 0.0305 0.3333 4.7 2qb6:B, 2qb7:A, 2qb7:B, 2qb8:A, 2qb8:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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