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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVIKKINSGVAHIIEPEIDRRLKEVLSLGKLKVTDRVEDLKGSNVFI
ICVQTPLSGDDPDLSYLERAIRTVAEVMDRGALVIIESTIPPGTTEKMARLLENLTGLREGVDFYVAHAPERVMPGRIFK
ELVYNSRIIGGVSEKAANLAEKLYRSFVKGRIFLTNATTAEMVKLMENTFRDVNIALANEFALLAHQYGVNVYEAIELAN
THPRVKIHTPGIGVGGHCLPKDPYLLLSNAKEDFGLIRIARRINERMPAFAAGLLFEALEKANIKPSEAIIAVLGLAYKG
GTDDTRNSPALKFVEIIRNSVKEVRTYDPYVRGTHDSLEKVVEGADAIVIATDHPEFKSVNWESIGKSMRHKIIIDGRNI
IKEPPVGFIFRGIGRGDV

The query sequence (length=418) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4r16:A 418 418 1.0000 1.0000 1.0000 0.0 4r16:B
2 3ojl:A 418 409 0.4306 0.4306 0.4401 2.72e-110 3ojl:B, 3ojo:A, 3ojo:B
3 4xr9:A 456 443 0.3134 0.2873 0.2957 3.62e-59
4 3vtf:A 432 428 0.3349 0.3241 0.3271 1.01e-51
5 3gg2:A 431 431 0.2990 0.2900 0.2900 6.74e-51 3gg2:D, 3gg2:B, 3gg2:C
6 4a7p:A 429 437 0.2895 0.2821 0.2769 2.03e-45 4a7p:B
7 1mfz:A 436 362 0.2512 0.2408 0.2901 6.81e-39 1mfz:B, 1mfz:C, 1mfz:D, 1muu:C, 1muu:A, 1muu:B, 1muu:D, 1mv8:B, 1mv8:A, 1mv8:C, 1mv8:D
8 2y0c:A 461 454 0.2943 0.2668 0.2709 1.75e-36 2y0c:B, 2y0c:C, 2y0c:D, 2y0d:A, 2y0d:B, 2y0d:C, 2y0d:D, 2y0e:A, 2y0e:B, 2y0e:C, 2y0e:D
9 6om8:D 468 461 0.2943 0.2628 0.2668 1.28e-31 6om8:A, 6om8:B, 6om8:C, 6om8:E, 6om8:F, 6om8:G, 6om8:H, 6om8:I, 6om8:J, 6om8:K, 6om8:L
10 3pjg:A 389 279 0.2177 0.2339 0.3262 3.67e-28 3pln:A, 3plr:A
11 3khu:B 467 470 0.2847 0.2548 0.2532 1.10e-24 6c4j:A, 6c4j:B, 6c4j:C, 6c4j:D, 6c4j:E, 6c4j:F, 6c4j:G, 6c4j:H, 6c4j:I, 6c4j:J, 6c4j:K, 6c4j:L, 6c58:A, 6c58:B, 6c58:C, 6c58:D, 6c58:E, 6c58:F, 6c5a:A, 6c5a:B, 6c5a:C, 6c5a:D, 6c5a:E, 6c5a:F, 6c5z:A, 6c5z:B, 6c5z:C, 6c5z:D, 6c5z:E, 6c5z:F, 3khu:A, 3khu:C, 3khu:D, 3khu:E, 3khu:F, 3prj:A, 3prj:B, 3prj:C, 3prj:D, 3prj:E, 3prj:F, 3ptz:A, 3ptz:B, 3ptz:C, 3ptz:D, 3ptz:E, 3ptz:F, 2q3e:A, 2q3e:B, 2q3e:C, 2q3e:D, 2q3e:E, 2q3e:F, 2q3e:G, 2q3e:H, 2q3e:I, 2q3e:J, 2q3e:K, 2q3e:L, 2qg4:A, 2qg4:B, 2qg4:C, 2qg4:D, 2qg4:E, 2qg4:F, 2qg4:G, 2qg4:H, 3tdk:A, 3tdk:B, 3tdk:G, 3tdk:H, 3tdk:L, 3tdk:K, 3tdk:F, 3tdk:E, 3tdk:D, 3tdk:C, 3tdk:J, 3tdk:I, 5tjh:A, 5tjh:B, 5tjh:C, 5tjh:D, 5tjh:E, 5tjh:F, 5vr8:A, 5vr8:B, 5vr8:C, 5vr8:D, 5vr8:E, 5vr8:F
12 7kws:A 390 365 0.2297 0.2462 0.2630 4.61e-24 7kws:B
13 4edf:A 431 453 0.2727 0.2645 0.2517 1.21e-22 4edf:B, 4edf:C, 4edf:D
14 1dli:A 402 396 0.2536 0.2637 0.2677 4.61e-17 1dlj:A
15 9bts:a 154 39 0.0359 0.0974 0.3846 0.14 9bts:b, 9bts:c, 9bts:d, 9bts:e, 9bts:f, 9bts:g, 9bts:h
16 4j34:B 390 32 0.0287 0.0308 0.3750 0.31 4j2w:A, 4j2w:B, 4j31:A, 4j31:B, 4j33:A, 4j33:B, 4j34:A, 4j36:A, 4j36:B, 5x6r:A, 5x6r:B
17 3f3s:A 312 35 0.0335 0.0449 0.4000 0.40 3f3s:B
18 6ruz:A 443 153 0.0981 0.0926 0.2680 0.52 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
19 5je8:B 294 33 0.0335 0.0476 0.4242 0.64 5je8:A, 5je8:C, 5je8:D
20 6aa8:E 281 72 0.0502 0.0747 0.2917 0.71 6aa8:F
21 5er0:A 450 50 0.0407 0.0378 0.3400 0.71 5er0:B, 5er0:C, 5er0:D, 5vn0:A, 5vn0:B, 5vn0:C, 5vn0:D, 5vn0:E, 5vn0:F, 5vn0:G, 5vn0:H, 5voh:A, 5voh:B, 5voh:C, 5voh:D
22 2i9p:B 296 215 0.1005 0.1419 0.1953 0.81 2i9p:A, 2i9p:C, 2i9p:D
23 4dyd:A 283 53 0.0431 0.0636 0.3396 1.1 4e13:A
24 1z82:A 312 83 0.0550 0.0737 0.2771 1.1 1z82:B
25 6vpb:B 324 126 0.0718 0.0926 0.2381 1.3
26 6m7d:A 412 113 0.0789 0.0801 0.2920 1.9
27 8oqs:B 735 87 0.0622 0.0354 0.2989 2.0 4b3i:A, 4b3i:B, 4b3j:A, 4b3j:B, 7o4s:A, 7o4s:B, 7o4t:A, 7o4t:B, 7o4u:A, 7o4u:B, 7o4v:B, 7o4v:A, 8opu:A, 8opu:B, 8opv:A, 8opv:B, 8oql:A, 8oql:B, 8oqn:A, 8oqn:B, 8oqo:A, 8oqo:B, 8oqp:A, 8oqp:B, 8oqq:A, 8oqq:B, 8oqr:A, 8oqr:B, 8oqs:A, 8oqt:B, 8oqt:A, 8oqu:A, 8oqu:B, 8oqv:A, 8oqv:B, 8pf8:A, 8pf8:B
28 2vou:A 393 56 0.0431 0.0458 0.3214 2.4 2vou:B, 2vou:C
29 4om8:A 309 81 0.0574 0.0777 0.2963 2.5 4om8:B
30 6hqw:B 307 53 0.0407 0.0554 0.3208 4.4
31 3p2y:A 345 37 0.0335 0.0406 0.3784 4.6
32 1c0i:A 363 25 0.0311 0.0358 0.5200 4.9 1c0k:A, 1c0l:A, 1c0p:A
33 6i1d:A 458 75 0.0455 0.0415 0.2533 5.1
34 1lss:A 132 47 0.0311 0.0985 0.2766 5.8 1lss:B, 1lss:C, 1lss:D
35 1d3y:B 290 67 0.0407 0.0586 0.2537 5.9 1d3y:A
36 2bc0:A 473 85 0.0646 0.0571 0.3176 6.2 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
37 5wp5:A 463 70 0.0478 0.0432 0.2857 6.9 5wp5:B
38 3adp:A 310 34 0.0311 0.0419 0.3824 7.2
39 1c7i:A 483 72 0.0407 0.0352 0.2361 7.5 1qe3:A
40 5zxu:A 337 67 0.0431 0.0534 0.2687 7.9
41 8b9d:2 576 158 0.0861 0.0625 0.2278 8.4
42 4nbw:A 253 24 0.0287 0.0474 0.5000 8.8 4nbw:B, 4nbw:C, 4nbw:D
43 1ps9:A 671 38 0.0359 0.0224 0.3947 9.5
44 5ayv:B 303 114 0.0694 0.0957 0.2544 9.9 5ayv:A, 5hws:A, 5hws:B, 5hws:C, 5hws:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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