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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRIAVIGGGSSYTPELVKGLLDISEDVRIDEVIFYDIDEEKQKIVVDFVKRLVKDRFKVLISDTFEGAVVDAKYVIFQFR
PGGLKGRENDEGIPLKYGLIGQETTGVGGFSAALRAFPIVEEYVDTVRKTSNATIVNFTNPSGHITEFVRNYLEYEKFIG
LCNVPINFIREIAEMFSARLEDVFLKYYGLNHLSFIEKVFVKGEDVTEKVFENLKLKEDFPTWFYDSVRLIVNPYLRYYL
MEKKMFKKISTHELRAREVMKIEKELFEKYRTAVEIPEELTKRGGSMYSTAAAHLIRDLETDEGKIHIVNTRNNGSIENL
PDDYVLEIPCYVRSGRVHTLSQGKGDHFALSFIHAVKMYERLTIEAYLKRSKKLALKALLSHPLGPDVEDAKDLLEEILE
ANREYVKLG

The query sequence (length=409) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1up7:A 414 412 1.0000 0.9879 0.9927 0.0 1up6:A, 1up6:C, 1up6:G, 1up7:B, 1up7:C, 1up7:D, 1up7:E, 1up7:F, 1up7:G, 1up7:H
2 5c3m:B 411 416 0.3765 0.3747 0.3702 2.99e-81 5c3m:A, 5c3m:C, 5c3m:D
3 6wbt:A 442 439 0.3447 0.3190 0.3212 2.59e-59 6wbt:B, 6wbt:C, 6wbt:D
4 6vc6:B 440 431 0.3007 0.2795 0.2854 1.31e-48 6vc6:A, 6vc6:C, 6vc6:D
5 1u8x:X 436 425 0.2861 0.2683 0.2753 1.02e-46
6 6dvv:A 435 440 0.3007 0.2828 0.2795 1.38e-44 6dux:A, 6dux:B, 6dvv:B
7 3fef:A 434 211 0.1516 0.1429 0.2938 2.22e-14 3fef:B, 3fef:C, 3fef:D
8 1vjt:A 471 472 0.2567 0.2229 0.2225 2.08e-10 7br4:A, 7brf:A, 7ctl:A, 7ctm:A, 6kcx:A, 3u95:A, 3u95:B, 3u95:C, 3u95:D, 3u95:E, 3u95:F
9 1obb:A 478 215 0.1271 0.1088 0.2419 0.035 1obb:B
10 1obb:A 478 94 0.0587 0.0502 0.2553 0.087 1obb:B
11 8x1c:K 394 106 0.0611 0.0635 0.2358 1.8
12 6sms:A 724 53 0.0391 0.0221 0.3019 1.8
13 2o03:A 129 60 0.0416 0.1318 0.2833 1.9
14 7azq:A 199 104 0.0611 0.1256 0.2404 2.2 7azq:E, 7azr:A, 7azr:E
15 3iu6:A 143 88 0.0587 0.1678 0.2727 2.2
16 8vsi:B 579 75 0.0465 0.0328 0.2533 2.6
17 7s8t:J 83 48 0.0416 0.2048 0.3542 4.8 7s8t:A, 7s8t:E, 7s8t:F, 7s8t:H, 7s8t:G, 7s8t:I
18 4nkt:B 308 83 0.0513 0.0682 0.2530 4.9
19 1civ:A 374 169 0.1051 0.1150 0.2544 6.3
20 1igt:B 444 20 0.0293 0.0270 0.6000 7.5 1igt:D, 2otu:B, 2otu:D, 2otu:F, 2otu:H, 2otw:B, 2otw:D, 2qhr:H, 6uqc:C, 6uqc:D, 6uqc:F, 5vaa:A, 5vaa:B, 3zo0:A
21 9j0u:A 286 30 0.0367 0.0524 0.5000 8.6 9j0v:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218