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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDIAFPIRHYVERKGIHFIAQS
AEQIDAEAQNITLADGNTVHYDYLMIATGPKLAFENVPGSDPHEGPVQSIATVDHAERAFAEYQALLREPGPIVIGAMAG
ASCFGPAYEYAMIVASDLKKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNCKVTKVEDNKMY
VTQVDEKGETIKEMVLPVKFGMMIPAFKGVPAVAGVEGLCNPGGFVLVDEHQRSKKYANIFAAGIAIAIPPVETTPVPTG
APKTGYMIESMVSAAVHNIKADLEGRKGEQTMGTWNAVCFADMGDRGAAFIALPQLKPRKVDVFAYGRWVHLAKVAFEKY
FIRKMKMGVSEPFYEKVLFKM

The query sequence (length=421) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3t2z:A 427 418 0.9905 0.9766 0.9976 0.0 3kpk:A, 3sx6:A, 3sxi:A, 3sy4:A, 3syi:A, 3sz0:A, 3szc:A, 3szf:A, 3szw:A, 3t0k:A, 3t14:A, 3t2k:A, 3t2y:A, 3t2z:B, 3t31:A
2 3hyv:A 429 403 0.3943 0.3869 0.4119 1.73e-97 3hyv:B, 3hyv:C, 3hyv:D, 3hyv:E, 3hyv:F, 3hyw:A, 3hyw:B, 3hyw:C, 3hyw:D, 3hyw:E, 3hyw:F, 3hyx:A, 3hyx:B, 3hyx:C, 3hyx:D, 3hyx:E, 3hyx:F
3 3h8i:A 356 345 0.2209 0.2612 0.2696 2.33e-27 3h8i:B, 3h8l:A, 3h8l:B
4 6bdo:D 395 144 0.1069 0.1139 0.3125 4.46e-13 6bdo:B, 6bdo:A, 6bdo:C, 5kmp:A, 5kmp:B, 5kmq:A, 5kmq:B, 5kmq:C, 5kmq:D, 5kmr:B, 5kmr:A, 5kmr:C, 5kmr:D, 5kms:A, 5kms:B, 5kms:C, 5kms:D, 4nwz:A, 4nwz:B, 4nwz:C, 4nwz:D, 5wed:B, 5wed:A, 5wed:C, 5wed:D
5 6mo6:B 414 317 0.1781 0.1812 0.2366 3.05e-08 8dhk:A, 8dhk:B, 6mo6:A, 6mo6:C, 6mo6:D, 6mp5:A, 6mp5:B, 6mp5:C, 6mp5:D, 6oi5:A, 6oi5:B, 6oi6:A, 6oi6:B, 6oib:A, 6oib:B, 6oic:A, 6oic:B, 6wh6:A, 6wh6:B
6 5n1t:A 393 164 0.1116 0.1196 0.2866 1.26e-07
7 5na1:A 398 144 0.0808 0.0854 0.2361 1.82e-07 5na4:A
8 3klj:A 378 120 0.0903 0.1005 0.3167 2.22e-07
9 5jwa:A 495 143 0.0926 0.0788 0.2727 3.39e-06 5jwa:H, 5jwb:A, 5jwb:H, 5jwc:A, 5jwc:H
10 5yjy:B 465 141 0.0879 0.0796 0.2624 9.05e-05 5yjw:A, 5yjx:A, 5yjx:B, 5yjy:A
11 3fg2:P 404 158 0.0950 0.0990 0.2532 2.40e-04
12 3fg2:P 404 107 0.0713 0.0743 0.2804 8.2
13 6ynv:e 417 300 0.1615 0.1631 0.2267 3.44e-04 6ynx:e, 6ynx:E, 6yny:e, 6yny:E, 6ynz:e, 6ynz:E, 6ynz:e3, 6ynz:E3
14 8c0z:E 424 241 0.1425 0.1415 0.2490 5.86e-04
15 4emj:A 406 119 0.0831 0.0862 0.2941 0.001 3ef6:A, 4emi:A
16 2bc0:A 473 142 0.0831 0.0740 0.2465 0.002 2bc0:B, 2bc1:A, 2bc1:B, 2bcp:A, 2bcp:B
17 4g6h:A 472 158 0.0879 0.0784 0.2342 0.005 4g6g:A, 4g6g:B, 4g6h:B, 4g73:A, 4g73:B, 4g74:A, 4g74:B, 4g9k:A, 4g9k:B, 4gap:A, 4gap:B, 4gav:A, 4gav:B
18 8pxk:A 403 153 0.0974 0.1017 0.2680 0.016 1d7y:A, 1f3p:A, 2gqw:A, 2gr0:A, 2gr1:A, 2gr2:A, 2gr3:A, 4h4p:A, 4h4q:A, 4h4r:A, 4h4s:A, 4h4t:A, 4h4u:A, 4h4v:A, 4h4w:A, 4h4x:A, 4h4y:A, 4h4z:A, 4h50:A, 8pxl:A, 2yvf:A, 2yvg:A, 2yvj:A, 2yvj:P
19 5z2g:A 477 35 0.0404 0.0356 0.4857 0.026 5z2g:B
20 1f8r:A 483 35 0.0404 0.0352 0.4857 0.039 1f8r:B, 1f8r:C, 1f8r:D, 1f8s:A, 1f8s:B, 1f8s:C, 1f8s:D, 1f8s:E, 1f8s:F, 1f8s:G, 1f8s:H, 2iid:A, 2iid:B, 2iid:C, 2iid:D
21 1reo:A 484 35 0.0380 0.0331 0.4571 0.046 1tdk:A, 1tdn:A, 1tdo:A
22 6ruz:A 443 235 0.1330 0.1264 0.2383 0.059 6ruz:B, 6ruz:C, 6ruz:D, 6rvb:A, 6rvb:B, 6rvb:C, 6rvb:D, 6rvh:A, 6rvh:B, 6rvh:C, 6rvh:D
23 3kve:A 484 35 0.0380 0.0331 0.4571 0.084 3kve:B, 3kve:C, 3kve:D
24 7xpi:A 363 26 0.0309 0.0358 0.5000 0.13 7ytl:A
25 1xhc:A 346 124 0.0831 0.1012 0.2823 0.16
26 8x38:A 430 33 0.0356 0.0349 0.4545 0.34
27 7mgo:A 489 244 0.1449 0.1247 0.2500 0.56
28 5ts5:A 483 35 0.0380 0.0331 0.4571 0.75 4e0v:A, 4e0v:B, 5ts5:B, 5ts5:C, 5ts5:D
29 2jae:A 478 88 0.0594 0.0523 0.2841 0.87 2jae:B, 2jb1:A, 2jb1:B, 2jb2:A, 2jb2:B, 2jb3:A, 2jb3:B
30 4dsg:A 473 34 0.0404 0.0359 0.5000 0.89 4dsg:B, 4dsh:A, 4dsh:B
31 1fcd:A 401 342 0.2162 0.2269 0.2661 2.0 1fcd:B
32 2c3c:A 522 256 0.1449 0.1169 0.2383 3.2 2c3c:B, 2c3d:A, 2c3d:B, 7mgn:A, 7mgn:B, 7mgo:B, 1mo9:A, 1mo9:B, 1mok:A, 1mok:B, 1mok:C, 1mok:D, 3q6j:A, 3q6j:B
33 2r9z:B 453 54 0.0404 0.0375 0.3148 3.3 2r9z:A, 2rab:A, 2rab:B
34 3ty7:B 454 47 0.0451 0.0419 0.4043 3.7
35 3lxd:A 409 63 0.0451 0.0465 0.3016 4.1
36 7b0n:F 460 67 0.0404 0.0370 0.2537 4.3 6gcs:B, 7o6y:B, 7o71:B, 6rfq:B, 6rfr:B, 6rfs:B, 6y79:B, 6yj4:F
37 1q1w:A 422 26 0.0261 0.0261 0.4231 5.3 3lb8:A, 3lb8:B, 1q1r:A, 1q1r:B, 1q1w:B
38 6pfz:A 541 78 0.0499 0.0388 0.2692 5.4 6pfz:D, 6pfz:C, 6pfz:B
39 6du7:A 448 52 0.0333 0.0312 0.2692 5.6 6du7:B, 6du7:C, 6du7:D, 6du7:E, 6du7:F, 6du7:G, 6du7:H
40 3qj4:A 335 99 0.0594 0.0746 0.2525 6.9 3qj4:B
41 1kcc:A 333 103 0.0618 0.0781 0.2524 7.4 1kcd:A
42 6ul2:A 526 32 0.0333 0.0266 0.4375 8.6 8tti:A, 8tti:B, 8tti:C, 8tti:D, 8ttj:A, 8ttj:B, 8ttj:C, 8ttj:D, 6ul2:B, 6ul2:C, 6ul2:D
43 5hy5:A 511 37 0.0356 0.0294 0.4054 9.2 5hy5:B
44 8a56:B 539 107 0.0689 0.0538 0.2710 9.4 8a56:A
45 6lg1:A 429 74 0.0451 0.0443 0.2568 9.7 6lg1:B
46 8i0w:W 440 42 0.0309 0.0295 0.3095 9.8 5yzg:W

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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