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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRGNQMLPNNHFNKGSMKFKNWFNQPMRALKRKEVREQKSKICYPNPLKKLRPVVRCCSMRYNKKVRLGRGFTKMEIEKA
GMDIKYAISVGIAVDLRRKNKNEEGLEENVKRLMDYKNKLKFFTTVREARDNKIEQYKGEIMKPVNIIPEVKGIKVEEIA
TIYG

The query sequence (length=164) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8p5d:LL0 164 164 1.0000 1.0000 1.0000 3.83e-119 8p60:LL0, 8p60:KL0, 7qca:LL0
2 6zu5:LL0 164 160 0.4939 0.4939 0.5062 1.95e-54
3 6rm3:LL0 162 161 0.4512 0.4568 0.4596 7.36e-47
4 7qep:M3 161 160 0.4390 0.4472 0.4500 9.54e-45
5 8fru:L 202 149 0.3902 0.3168 0.4295 2.53e-35 8br8:LM, 8brm:LM, 8bsi:LM, 8bsj:LM, 8btd:LM, 8btr:LM, 7pwg:L, 7pwo:L2
6 9bh5:CL 204 162 0.4207 0.3382 0.4259 7.87e-35 9cai:CL
7 4v6w:CL 210 124 0.3537 0.2762 0.4677 1.45e-34 6xu6:CL, 6xu7:CL, 6xu8:CL
8 4v7e:CL 208 125 0.3537 0.2788 0.4640 1.31e-33 8ip8:KB, 8ipa:KB, 8ipb:KB, 8jiv:CL
9 8eug:L 202 119 0.3232 0.2624 0.4454 7.08e-32 8esq:L, 8esr:L, 8etc:L, 8etg:L, 8eth:L, 8eti:L, 8etj:L, 8eui:L, 8eup:L, 8euy:L, 8ev3:L
10 7oya:L1 197 122 0.3476 0.2893 0.4672 1.32e-29 7oyb:L1
11 7qiw:N 204 125 0.3415 0.2745 0.4480 1.62e-29 8azw:D, 8b2l:D3, 7qiz:N
12 5it7:LL 197 115 0.3171 0.2640 0.4522 1.12e-28 6uz7:AL
13 8c3a:t 200 158 0.3659 0.3000 0.3797 1.26e-28 8c3a:BG, 8cq7:t, 8cq7:BG, 8cqw:t, 8cqw:BG, 8cre:t, 8cre:BG, 8oeq:t, 8oeq:BG, 7pzy:t, 7q08:t, 7q0f:t, 7q0p:t, 7q0r:t, 8q5i:t
14 7oyc:L1 199 122 0.3354 0.2764 0.4508 3.76e-28
15 8rxh:LI 214 129 0.3476 0.2664 0.4419 6.06e-28 8a98:I, 6az3:I, 3jcs:I, 8ovj:I, 8rxx:LI
16 5t2a:L 179 129 0.3476 0.3184 0.4419 1.20e-27 8a3w:I
17 4v8p:AU 203 124 0.3232 0.2611 0.4274 1.96e-27 4v8p:DU, 4v8p:FU, 4v8p:HU
18 7olc:LL 209 124 0.3476 0.2727 0.4597 2.22e-27 8i9p:LL, 8i9r:LL, 8i9t:LL, 8i9v:LL, 8i9w:LL, 8i9x:LL, 8i9y:LL, 8i9z:LL, 8ia0:LL, 7old:LL, 8oo0:LL, 8pv1:LL, 8pv2:LL, 8pv3:LL, 8pv4:LL, 8pv5:LL, 8pv6:LL, 8pv7:LL, 8pv8:LL, 8pvk:LL, 8pvl:LL, 7z3n:LL, 7z3o:LL
19 7r81:N1 213 152 0.3476 0.2676 0.3750 2.41e-27
20 5xxb:K 199 121 0.3232 0.2663 0.4380 3.78e-27
21 8ova:BN 215 129 0.3598 0.2744 0.4574 5.78e-26 8ove:BN, 4v8m:BN
22 6zj3:LX 219 131 0.3415 0.2557 0.4275 7.74e-26
23 8hfr:LL 198 115 0.3049 0.2525 0.4348 6.74e-25 8aaf:t, 8agt:t, 8agu:t, 8agv:t, 8agw:t, 8agx:t, 8agz:t, 5apn:L, 5apo:L, 7azy:k, 7b7d:LN, 8bip:LL, 8bjq:LL, 8bn3:M3, 8bqd:AJ, 8bqx:AJ, 7bt6:L, 7btb:L, 6c0f:L, 6cb1:L, 8ccs:OO, 8cdl:OO, 8cdr:OO, 8ceh:OO, 8cf5:OO, 8cg8:OO, 8cgn:OO, 8civ:OO, 8cku:OO, 8cmj:OO, 5dat:M3, 5dat:m3, 5dc3:M3, 5dc3:m3, 5dge:M3, 5dge:m3, 5dgf:M3, 5dgf:m3, 5dgv:M3, 5dgv:m3, 8e5t:L, 6elz:L, 6em1:L, 6em3:L, 6em4:L, 6em5:L, 8eub:AL, 8evp:AL, 8evq:AL, 8evr:AL, 8evs:AL, 8evt:AL, 8ewb:AL, 8ewc:AL, 5fci:M3, 5fci:m3, 5fcj:M3, 5fcj:m3, 6ft6:L, 5gak:N, 6gq1:L, 6gqb:L, 6gqv:L, 5h4p:L, 6hd7:N, 6hhq:t, 6hhq:CN, 5i4l:M3, 5i4l:m3, 6i7o:AJ, 6i7o:XJ, 3j6x:53, 3j6y:53, 3j77:63, 3j78:63, 3jct:L, 5jcs:L, 5juo:Q, 5jup:Q, 5jus:Q, 5jut:Q, 5juu:Q, 8k2d:LL, 8k82:LL, 5lyb:M3, 5lyb:m3, 5m1j:L5, 6m62:L, 5mc6:AJ, 5mei:t, 5mei:CN, 7mpi:AL, 7mpj:AL, 6n8j:L, 6n8k:L, 6n8l:L, 6n8m:N, 6n8n:N, 6n8o:N, 7n8b:AL, 7nac:L, 5ndg:M3, 5ndg:m3, 5ndv:M3, 5ndv:m3, 5ndw:M3, 5ndw:m3, 7nrc:LN, 7nrd:LN, 5obm:M3, 5obm:m3, 7of1:L, 7oh3:L, 7ohp:L, 7ohq:L, 7ohr:L, 7ohs:L, 7ohu:L, 7ohv:L, 7ohw:L, 7ohx:L, 7ohy:L, 6oig:L, 5on6:t, 5on6:CN, 7osa:eL13, 7osm:eL13, 8p8m:JT, 8p8n:JT, 8p8u:JT, 8pfr:JT, 6q8y:AJ, 6qik:K, 6qt0:K, 6qtz:K, 7r7a:L, 6r84:N, 6r86:N, 6r87:N, 6ri5:K, 7rr5:LL, 6rzz:K, 6s05:K, 6s47:AN, 6snt:r, 6sv4:AJ, 6sv4:XJ, 6sv4:zJ, 6t4q:LL, 5t62:N, 5t6r:N, 6t7i:LL, 6t7t:LL, 6t83:Ly, 6t83:Na, 5tbw:t, 5tbw:CN, 6tb3:AJ, 5tga:M3, 5tga:m3, 5tgm:M3, 5tgm:m3, 6tnu:AJ, 7too:AL13, 7top:AL13, 7u0h:L, 4u3m:M3, 4u3m:m3, 4u3n:M3, 4u3n:m3, 4u3u:M3, 4u3u:m3, 4u4n:M3, 4u4n:m3, 4u4o:M3, 4u4o:m3, 4u4q:M3, 4u4q:m3, 4u4r:M3, 4u4r:m3, 4u4u:M3, 4u4u:m3, 4u4y:M3, 4u4y:m3, 4u4z:M3, 4u4z:m3, 4u50:M3, 4u50:m3, 4u51:M3, 4u51:m3, 4u52:M3, 4u52:m3, 4u53:M3, 4u53:m3, 4u55:M3, 4u55:m3, 4u56:M3, 4u56:m3, 4u6f:M3, 4u6f:m3, 7ug6:L, 7uoo:L, 7uqb:L, 7uqz:L, 7v08:L, 4v7f:K, 4v88:BL, 4v88:DL, 4v8t:L, 4v8y:BL, 4v8z:BL, 8v83:L, 8v84:L, 8v87:L, 4v91:L, 6woo:L, 6xiq:L, 6xir:L, 8y0u:LL, 6ylg:L, 6ylh:L, 6ylx:L, 6yly:L, 5z3g:P, 7z34:L, 6z6j:LL, 6z6k:LL, 7zpq:BK, 7zrs:BK, 7zs5:BM, 7zuw:BK, 7zux:EK, 7zw0:LO
24 5t5h:N 172 116 0.3293 0.3140 0.4655 8.00e-25
25 7a01:a7 210 122 0.3171 0.2476 0.4262 1.01e-21 8a3d:r, 5aj0:AL, 8b5l:L, 8b6c:L, 9bdl:AL13, 9bdn:AL13, 9bdp:AL13, 7bhp:LL, 8bhf:t3, 8bpo:K2, 8btk:BL, 7cpu:LL, 7cpv:LL, 4d5y:L, 4d67:L, 6d90:L, 6d9j:L, 9f1b:BL, 9f1c:BL, 9f1d:BL, 7f5s:LL, 8fkp:L6, 8fkq:L6, 8fkr:L6, 8fks:L6, 8fkt:L6, 8fku:L6, 8fkv:L6, 8fkw:L6, 8fkx:L6, 8fky:L6, 8fkz:L6, 8fl2:L6, 8fl3:L6, 8fl4:L6, 8fl6:L6, 8fl7:L6, 8fl9:L6, 8fla:L6, 8flb:L6, 8flc:L6, 8fld:L6, 8fle:L6, 8flf:L6, 6frk:L, 6ftg:L, 6fti:L, 6ftj:L, 8g5y:LL, 8g5z:LL, 8g60:LL, 8g61:LL, 8g6j:LL, 8glp:LL, 6gz3:AL, 6gz4:AL, 6gz5:AL, 6hcf:L3, 6hcj:L3, 6hcm:L3, 6hcq:L3, 8idt:Q, 8idy:Q, 8ie3:Q, 8ifd:2F, 8ife:2F, 8ine:Q, 8inf:Q, 8ink:Q, 6ip5:2F, 6ip6:2F, 6ip8:2F, 8ipd:Q, 8ipx:Q, 8ipy:Q, 8ir1:Q, 8ir3:Q, 3j7o:L, 3j7p:L, 3j7q:L, 3j7r:L, 3j92:L, 3jag:L, 3jah:L, 3jai:L, 3jaj:L, 3jan:L, 8jdj:Q, 8jdk:Q, 8jdl:Q, 8jdm:Q, 8k2c:LL, 5lks:LL, 6lqm:Q, 6lsr:Q, 6lss:Q, 7ls1:F1, 7ls2:F1, 6lu8:Q, 5lzs:L, 5lzt:L, 5lzu:L, 5lzv:L, 5lzw:L, 5lzx:L, 5lzy:L, 5lzz:L, 7mdz:L, 6mtb:L, 6mtc:L, 6mtd:L, 6mte:L, 7nfx:L, 7nwg:L3, 7nwh:L, 7nwi:L, 7o7y:BL, 7o7z:BL, 7o80:BL, 7o81:BL, 7obr:L, 8ohd:LL, 8oj0:LL, 8oj5:LL, 8oj8:LL, 6ole:M, 6olf:M, 6olg:AL, 6oli:M, 6olz:AL, 6om0:M, 6om7:M, 7ow7:r, 7oyd:L, 8p2k:BL, 6p5i:AL, 6p5j:AL, 6p5k:AL, 6p5n:AL, 8q7z:BL, 8q87:BL, 8qfd:L, 7qgg:M, 8qoi:LL, 7qvp:ML, 7qvp:LL, 7qwq:L, 7qwr:L, 7qws:L, 6qzp:LL, 6r5q:L, 6r6g:L, 6r6p:L, 6r7q:L, 8rjb:L, 8rjc:L, 8rjd:L, 8scb:L, 6sgc:L2, 6swa:K, 5t2c:r, 6t59:L3, 7tm3:L, 7toq:AL13, 7tor:AL13, 7tut:L, 7ucj:L, 7uck:L, 4ug0:LL, 4ujc:BL, 4ujd:AL, 4uje:CL, 4v6x:CL, 6w6l:M, 6xa1:LL, 7xnx:LL, 7xny:LL, 8xsx:LL, 8xsy:LL, 8xsz:LL, 6y0g:LL, 8y0w:LL, 8y0x:LL, 6y2l:LL, 6y57:LL, 6y6x:LL, 8yoo:LL, 8yop:LL, 6z6l:LL, 6z6m:LL, 6z6n:LL, 7zjw:LO, 7zjx:LO, 6zm7:LL, 6zme:LL, 6zmi:LL, 6zmo:LL, 6zvk:a7
26 5xy3:L 185 119 0.3110 0.2757 0.4286 4.43e-21
27 3j79:L 211 125 0.2866 0.2227 0.3760 6.91e-20 3jbn:AL, 3jbo:AL, 3jbp:AL, 8tpu:AL, 5umd:L
28 3ldg:A 377 49 0.1280 0.0557 0.4286 2.4
29 5lug:A 207 34 0.0732 0.0580 0.3529 5.3 5lug:D, 5lug:C, 5lug:B
30 3cg4:A 126 91 0.1524 0.1984 0.2747 5.4
31 7ajt:JA 812 31 0.0854 0.0172 0.4516 6.2 7d63:RL, 6ke6:RL, 6lqp:RL, 6lqq:RL, 6lqr:RL, 6lqu:RL, 6lqv:RL, 7suk:LX, 6zqb:JA, 6zqc:JA
32 4ofm:B 206 49 0.0854 0.0680 0.2857 7.1 4ofm:A, 4ofm:C, 4ofm:D, 4ofn:A, 4ofn:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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