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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MRERTEARRRRIEEVLRRRQPDLTVLLENVHKPHNLSAILRTCDAVGVLEAHAVNPTGGVPTFNETSGGSHKWVYLRVHP
DLHEAFRFLKERGFTVYATALREDARDFREVDYTKPTAVLFGAEKWGVSEEALALADGAIKIPMLGMVQSLNVSVAAAVI
LFEAQRQRLKAGLYDRPRLDPELYQKVLADW

The query sequence (length=191) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1v2x:A 191 191 1.0000 1.0000 1.0000 2.87e-141
2 7edc:A 236 182 0.5288 0.4280 0.5549 7.12e-64
3 4x3l:A 260 150 0.3141 0.2308 0.4000 3.31e-15 4x3l:B, 4x3m:A, 4x3m:B
4 5kzk:A 262 151 0.2565 0.1870 0.3245 5.04e-13 5kzk:B, 5l0z:A, 5l0z:B
5 2ha8:A 159 151 0.2094 0.2516 0.2649 1.37e-12 2ha8:B
6 5co4:B 161 161 0.3089 0.3665 0.3665 1.03e-11 5co4:A
7 1x7p:A 265 161 0.2565 0.1849 0.3043 1.79e-09 1x7p:B
8 4pzk:A 159 158 0.2670 0.3208 0.3228 6.97e-09 4pzk:B
9 8w9u:A 152 147 0.2147 0.2697 0.2789 2.21e-08 8w9u:B
10 7oi6:1 257 162 0.2356 0.1751 0.2778 2.43e-08 7oi6:z
11 3nk7:B 267 142 0.2147 0.1536 0.2887 4.12e-06 3nk7:A
12 3gyq:A 261 166 0.2356 0.1724 0.2711 6.60e-06 3gyq:B
13 7e3q:B 159 139 0.1937 0.2327 0.2662 8.04e-06
14 4jal:A 156 150 0.2042 0.2500 0.2600 5.97e-04 4jal:B
15 4kgn:C 157 154 0.2199 0.2675 0.2727 0.001 4kgn:E, 4kgn:G
16 1mxi:A 156 150 0.1937 0.2372 0.2467 0.002
17 3n4k:A 163 153 0.2199 0.2577 0.2745 0.002
18 4cng:A 156 143 0.1728 0.2115 0.2308 0.004 4cnf:A, 4cng:B
19 4kgn:A 139 150 0.2094 0.2878 0.2667 0.009
20 4xbo:A 228 48 0.0838 0.0702 0.3333 2.5 4cne:A, 4cne:B, 4xbo:B
21 6fxr:A 700 116 0.1466 0.0400 0.2414 3.1 6fxk:A, 6fxm:A, 6fxt:A, 6fxx:A, 6fxy:A, 8one:A, 6te3:A, 6tec:A, 6tes:A, 6teu:A, 6tex:A, 6tez:A, 6wfv:A
22 1cjx:A 352 53 0.0890 0.0483 0.3208 3.6 1cjx:D, 1cjx:B, 1cjx:C, 7x8e:A, 7x8e:B, 7x8e:C, 7x8e:D, 7x8e:E, 7x8e:F, 7x8e:G, 7x8e:H, 7xnt:G, 7xnt:A, 7xnt:B
23 7z79:B 306 65 0.1099 0.0686 0.3231 7.6 7z79:A, 7z79:C, 7z79:D, 7z79:E, 7z79:F
24 5gm8:B 173 163 0.2042 0.2254 0.2393 8.0 5gm8:A, 5gm8:C, 5gm8:D
25 1yag:A 372 25 0.0576 0.0296 0.4400 9.2 8a5a:V, 8a5d:V, 8a5o:V, 8a5p:V, 8a5q:V, 5i9e:D, 5nbl:C, 5nbl:D, 5nbm:C, 5nbm:D, 5nbn:C, 5nbn:D, 8thx:A, 8thx:B, 8thx:C, 8thx:D, 8thx:E, 8thy:A, 8thy:B, 8thy:C, 8thy:D, 8thy:E, 8ti3:A, 8ti3:B, 8ti3:C, 8ti3:D, 8ti3:E, 7vvy:G, 7vvz:G, 1yvn:A
26 4pl7:A 382 25 0.0576 0.0288 0.4400 9.6 4pl7:B, 7zvw:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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