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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MQWSGARALEALLTVAGELRGPPLQLDTGQLLKIAKRGGVTAVEAVHAWRNALTGAPLNLTPEQVVAIASHDGGKQALET
VQRLLPVLCQAHGLTPQQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPEQVVAIASHDGGKQALETVQALLPVLCQAH
GLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPQQVVAIASNGGGKQALETVQRLLPVLCQAHGLTPQQVVAIAS
RGGKQALETVQRLLPVLCQAHGLTPQQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPQQVVAIASHDGGKQALETVQR
LLPVLCQAHGLTPQQVVAIASNNGGKQALETVQRLLPVLCQAHGLTPEQVVAIASNGGGKQALETVQRLLPVLCQAHGLT
PEQVVAIASHDGGKQALETVQRLLPVLCQAHGLTPQQVVAIASNGGGRPALESIVAQLSRPDPALAALTNDHLVALACLG
GRPALDAVKKLEH

The query sequence (length=493) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4gjp:A 497 494 0.9939 0.9859 0.9919 0.0 4gg4:A, 4gjp:B, 4gjr:A, 6jtq:A, 6jtq:B, 6jvz:A, 6jvz:B, 6jw0:A, 6jw0:B, 6jw1:A, 6jw1:B, 6jw2:A, 6jw2:B, 6jw2:E, 6jw2:H, 6jw3:A, 6jw3:B, 6jw3:E, 6jw3:H, 6jw4:A, 6jw4:B, 6jw4:E, 6jw4:H, 6jw5:A, 6jw5:B, 6jw5:E, 6jw5:H, 6lew:A, 4osh:B, 4osh:A, 4osi:A, 4osj:A, 4osj:B, 4osk:A, 4osk:B, 4osl:A, 4osl:B, 4osm:A, 4osm:B, 4osq:A, 4osr:A, 4oss:A, 4ost:B, 4ost:A, 4osv:A, 4osw:A, 4osz:B, 4osz:A, 4ot0:A, 4ot0:B, 4ot3:B, 4ot3:A, 4oto:A, 3v6t:A
2 2ypf:A 675 495 0.8925 0.6519 0.8889 0.0 4gjr:B, 6lew:B, 4osi:B, 4osq:B, 4osr:B, 4oss:B, 4osv:B, 4osw:B, 4oto:B, 3v6t:B
3 2ypf:A 675 496 0.8093 0.5911 0.8044 0.0 4gjr:B, 6lew:B, 4osi:B, 4osq:B, 4osr:B, 4oss:B, 4osv:B, 4osw:B, 4oto:B, 3v6t:B
4 2ypf:A 675 428 0.7465 0.5452 0.8598 0.0 4gjr:B, 6lew:B, 4osi:B, 4osq:B, 4osr:B, 4oss:B, 4osv:B, 4osw:B, 4oto:B, 3v6t:B
5 2ypf:A 675 486 0.7282 0.5319 0.7387 0.0 4gjr:B, 6lew:B, 4osi:B, 4osq:B, 4osr:B, 4oss:B, 4osv:B, 4osw:B, 4oto:B, 3v6t:B
6 2ypf:A 675 411 0.5538 0.4044 0.6642 1.19e-145 4gjr:B, 6lew:B, 4osi:B, 4osq:B, 4osr:B, 4oss:B, 4osv:B, 4osw:B, 4oto:B, 3v6t:B
7 3ugm:A 854 495 0.8621 0.4977 0.8586 0.0
8 3ugm:A 854 493 0.7972 0.4602 0.7972 0.0
9 3ugm:A 854 532 0.7789 0.4496 0.7218 0.0
10 3ugm:A 854 423 0.7181 0.4145 0.8369 0.0
11 3ugm:A 854 338 0.4787 0.2763 0.6982 2.69e-123
12 4cja:A 753 436 0.3205 0.2098 0.3624 3.43e-53
13 4cja:A 753 456 0.3347 0.2191 0.3618 5.73e-50
14 4cja:A 753 399 0.2921 0.1912 0.3609 1.96e-49
15 5d7l:C 242 69 0.0467 0.0950 0.3333 0.36
16 7tve:D 445 143 0.0629 0.0697 0.2168 0.58
17 5jfs:A 277 70 0.0385 0.0686 0.2714 3.4 4aoj:A, 4aoj:B, 4aoj:C, 6dkb:A, 6dkw:B, 6iqn:B, 5jfv:A, 5jfw:A, 5jfx:A
18 7r81:B2 209 60 0.0385 0.0909 0.3167 3.5 7olc:SA, 7old:SA, 8oo0:SA, 7z3n:SA, 7z3o:SA
19 7w0k:A 457 79 0.0365 0.0394 0.2278 8.0 7w0z:A, 7w10:A, 7w1b:A, 7w1h:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218