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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MQKLLSPRTARHARLFRLAGKLADSGSPGVPKSDGERLVWVNSHVRRDKDISLSQEEERIRELMMPLHGNLFYFREYPMY
PGEYVPAEHNTLSSLRDELRLDLTAQSLKEAWMRVSGGVYFQSVDEYYASVDGLDAEQIGEVLAALFPELNCYEAQALVQ
RTLECISRPVSAASRQLSRTITAEAVGLDNAPGHYTNFLEWMGRLTETRAFKTEHALFEFSRRKFNRDDVRVMFENYRLM
SKATLLADSADSYSHFYTVLKDFARKVAGQIGVRIDEAEVDPETGIAVGRGCADGEKYHFTALLRENRDHNGIITVMGKP
LSLVLDNKAWLMEMVLMPFDEANLDYRDFDAHIVSEGHAMPSIANEIAAFALRMAVANALVKLIPLTRIPLKKSGLLSVD
RRRERGQFPGYLDGKKVKRRFAKR

The query sequence (length=424) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7pub:CI 427 427 0.9953 0.9883 0.9883 0.0 6hiv:CI, 6hiw:CI, 7pua:CI, 6sg9:CI, 6sgb:CI
2 7aor:d 445 445 0.8608 0.8202 0.8202 0.0
3 7ane:d 343 346 0.6486 0.8017 0.7948 0.0
4 6hiz:CI 222 155 0.3656 0.6982 1.0000 1.39e-109
5 6hiz:CI 222 68 0.1580 0.3018 0.9853 8.77e-39
6 5mmj:i 144 99 0.0755 0.2222 0.3232 0.004 6eri:BI, 5mmm:i, 4v61:AI, 5x8p:i, 5x8r:i
7 8uu5:i 127 111 0.0755 0.2520 0.2883 0.056 7nhn:j, 8uu4:i, 8uu6:i, 8uu7:i, 8uu8:i, 8uu9:i
8 7nhk:j 128 115 0.0849 0.2812 0.3130 0.13 6o8w:i, 6o8x:i, 6o8y:i, 6o8z:i, 6o90:i, 7p7q:j, 7p7r:j, 7p7s:j, 7p7t:j, 7p7u:j, 6w6p:i, 6wua:i
9 5myj:AI 129 114 0.0731 0.2403 0.2719 0.23
10 3j9w:AI 130 57 0.0519 0.1692 0.3860 0.30 8buu:i, 8cdu:J, 8cdv:J, 8cec:N, 8ced:J, 8cee:J, 6ha1:i, 6ha8:i, 6htq:i, 5njt:I, 7o5b:I, 8qcq:i, 7qgu:n, 7qh4:m, 8qpp:I, 7qv1:i, 7qv2:i, 7qv3:i, 8r55:I
11 6ns2:A 634 89 0.0519 0.0347 0.2472 0.37 6ns2:C
12 8bh6:i 128 113 0.0731 0.2422 0.2743 0.55 7aso:H, 7asp:q, 7bge:i, 8bh7:i, 8byv:i, 6fxc:Ai, 6fxc:Bi, 7kwg:i, 5li0:i, 5nd8:i, 5nd9:i, 5ngm:Ai, 7nhl:j, 7nhm:j, 8p2f:j, 8p2g:j, 8p2h:j, 7p48:i, 6s0x:i, 6s13:i, 5tcu:SH, 8y38:i, 8y39:i, 6yef:i
13 8aq2:A 520 118 0.0778 0.0635 0.2797 0.75
14 6ns4:A 685 71 0.0425 0.0263 0.2535 1.4 6ns3:A, 6ns4:B, 6ns5:A, 6ns5:B, 6ns6:A, 6ns6:B
15 6lpf:B 1006 38 0.0330 0.0139 0.3684 1.8 6kid:A, 6kie:A, 6kqy:A, 6kr7:A, 6lpf:A, 6lr6:A, 6lr6:B
16 7kgb:i 127 32 0.0354 0.1181 0.4688 2.4 6dzi:4, 6dzk:I, 8fr8:k, 7msc:i, 7msh:i, 7msm:i, 7msz:i, 7mt2:i, 7mt3:i, 7mt7:i, 5o5j:I, 5o61:BI, 7sfr:i, 5v93:i, 8v9j:i, 8v9k:i, 8v9l:i, 8whx:j, 8wi7:j, 8wi9:j, 8wib:j, 8wid:j, 8wif:j, 5xyu:I, 5zeb:i, 5zep:i, 5zeu:i
17 2zy4:F 535 59 0.0590 0.0467 0.4237 2.8 3fdd:A, 2zy3:A, 2zy3:B, 2zy3:C, 2zy3:D, 2zy3:E, 2zy3:F, 2zy4:A, 2zy4:B, 2zy4:C, 2zy4:D, 2zy4:E, 2zy5:A, 2zy5:B, 2zy5:C, 2zy5:D, 2zy5:E, 2zy5:F
18 1vbg:A 874 42 0.0354 0.0172 0.3571 3.7 1vbh:A
19 7t30:A 666 116 0.0708 0.0450 0.2586 5.4 7t2r:A, 7t2r:F, 7t30:F
20 8rdv:F 126 93 0.0566 0.1905 0.2581 5.7 8rd8:F, 8rdw:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218