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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MQKDLHPKAVPCKIIYQGQVVMETMSTRPEIHVDVWSGVHPFWTGEERFLDTEGRVDKFNKRFGDSYRRGSKK

The query sequence (length=73) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1nkw:Y 73 73 1.0000 1.0000 1.0000 8.88e-52 1nwx:Y, 1nwy:Y, 1sm1:Y, 4v4g:B1, 4v4g:D1, 4v4g:F1, 4v4g:H1, 4v4g:J1, 4v4p:A4, 4v4r:B4, 4v4s:B4, 4v4t:B4, 1xbp:Y
2 5a9z:Aa 71 70 0.5479 0.5634 0.5714 4.13e-27 5aa0:Aa, 7azo:L31A, 7azo:L31B, 7azs:L31A, 7azs:L31B, 9b00:14, 9b00:24, 6b4v:BA, 6b4v:FC, 6boh:BA, 6boh:GC, 6bok:BA, 6bok:EC, 6buw:R4, 6buw:Y4, 6bz6:R4, 6bz6:Y4, 6bz7:R4, 6bz7:Y4, 6bz8:R4, 6bz8:Y4, 6cae:14, 6cae:24, 6cfj:14, 6cfj:24, 6cfk:14, 6cfk:24, 6cfl:14, 6cfl:24, 8cvj:14, 8cvj:24, 8cvk:14, 8cvk:24, 8cvl:14, 8cvl:24, 5czp:Y4, 5czp:R4, 6czr:14, 6czr:24, 5dfe:Y4, 5dfe:R4, 5dox:14, 5dox:24, 5doy:14, 5doy:24, 5e7k:M8, 5e81:M8, 8ekb:14, 8ekb:24, 5el4:M8, 5el5:M8, 5el6:M8, 5el7:M8, 8ev6:14, 8ev6:24, 8ev7:14, 8ev7:24, 5f8k:14, 5f8k:24, 8fc1:14, 8fc1:24, 8fc2:14, 8fc2:24, 8fc3:14, 8fc3:24, 8fc4:14, 8fc4:24, 8fc5:14, 8fc5:24, 8fc6:14, 8fc6:24, 5fdu:14, 5fdu:24, 5fdv:14, 5fdv:24, 6fkr:14, 6fkr:24, 8fom:R4, 8fom:Y4, 8fon:R4, 8fon:Y4, 8g29:14, 8g29:24, 8g2a:14, 8g2a:24, 8g2b:14, 8g2b:24, 8g2c:14, 8g2c:24, 8g2d:14, 8g2d:24, 6gsj:M8, 6gsk:M8, 6gsl:M8, 6gzq:Z1, 6gzx:Z1, 6gzx:Z2, 6gzz:Z1, 6gzz:Z2, 5hau:12, 5hau:22, 5hcp:14, 5hcp:24, 5hcq:14, 5hcq:24, 5hcr:14, 5hcr:24, 5hd1:14, 5hd1:24, 5ib7:M8, 5ib8:M8, 5ibb:M8, 5ibb:I5, 5imq:v, 5imr:v, 5j30:R4, 5j30:Y4, 5j3c:R4, 5j3c:Y4, 5j4b:14, 5j4b:24, 5j4c:14, 5j4c:24, 5j4d:BA, 5j4d:GC, 5j8b:4, 7jql:14, 7jql:24, 7jqm:14, 7jqm:24, 4l47:R4, 4l47:Y4, 4l71:R4, 4l71:Y4, 4lel:R4, 4lel:Y4, 4lfz:R4, 4lfz:Y4, 7lh5:D4, 4lnt:R4, 4lnt:Y4, 4lsk:R4, 4lsk:Y4, 4lt8:R4, 4lt8:Y4, 7md7:14, 7md7:24, 6n9e:14, 6n9e:24, 6n9f:14, 6n9f:24, 5ndj:M8, 5ndj:I5, 5ndk:M8, 5ndk:I5, 6nd5:14, 6nd5:24, 6nd6:14, 6nd6:24, 6ndk:R4, 6ndk:Y4, 6nsh:R4, 6nsh:Y4, 6nta:R4, 6nta:Y4, 6nuo:R4, 6nuo:Y4, 6nwy:Y4, 6o3m:R4, 6o3m:Y4, 6o97:14, 6o97:24, 6of1:14, 6of1:24, 6of6:R4, 6of6:Y4, 6oj2:R4, 6oj2:Y4, 6ope:R4, 6ope:Y4, 6ord:R4, 6ord:Y4, 6osi:R4, 5ot7:Z, 6otr:R4, 6otr:Y4, 6oxa:R4, 6oxa:Y4, 6oxi:R4, 6oxi:Y4, 4p6f:R4, 4p6f:Y4, 4p70:R4, 4p70:Y4, 6q95:a, 6qnq:M8, 6qnq:I5, 6qnr:M8, 6qnr:I5, 7rq8:14, 7rq8:24, 7rq9:14, 7rq9:24, 7rqa:14, 7rqa:24, 7rqb:14, 7rqb:24, 7rqc:14, 7rqc:24, 7rqd:14, 7rqd:24, 7rqe:14, 7rqe:24, 8t8b:14, 8t8b:24, 8t8c:14, 8t8c:24, 4tua:R4, 4tua:Y4, 4tub:R4, 4tub:Y4, 4tuc:R4, 4tuc:Y4, 4tud:R4, 4tud:Y4, 4tue:R4, 4tue:Y4, 7u2h:14, 7u2h:24, 7u2i:14, 7u2i:24, 7u2j:14, 7u2j:24, 6ucq:14, 6ucq:24, 8ud6:14, 8ud6:24, 8ud7:14, 8ud7:24, 8ud8:14, 8ud8:24, 6uo1:14, 6uo1:24, 5uq7:4, 5uq8:4, 8uvr:14, 8uvr:24, 8uvs:14, 8uvs:24, 4v4x:B3, 4v4y:B3, 4v4z:B3, 4v51:B4, 4v5a:B4, 4v5a:D4, 4v5f:B4, 4v5f:D4, 4v5m:B4, 4v5n:B4, 4v5p:D4, 4v5q:B4, 4v5r:B4, 4v5r:D4, 4v67:B4, 4v68:B4, 4v6f:D4, 4v6f:A4, 4v6g:B4, 4v6g:D4, 4v7j:A4, 4v7j:B4, 4v7k:A4, 4v7k:B4, 4v7l:B4, 4v7l:D4, 4v7m:B4, 4v7m:D4, 4v7w:B4, 4v7w:D4, 4v7x:B4, 4v7x:D4, 4v7y:B4, 4v7y:D4, 4v87:A4, 4v87:D4, 4v8a:A4, 4v8a:B4, 4v8b:B4, 4v8c:A4, 4v8c:B4, 4v8d:B4, 4v8d:D4, 4v8e:A4, 4v8e:C4, 4v8f:A4, 4v8f:D4, 4v8g:B4, 4v8g:D4, 4v8h:B4, 4v8h:D4, 4v8i:B4, 4v8i:D4, 4v8n:B4, 4v8n:D4, 4v8u:B4, 4v8u:D4, 4v8x:B4, 4v8x:D4, 5v8i:14, 5v8i:24, 4v90:B4, 4v95:B4, 4v95:D4, 4v97:D4, 4v9a:B4, 4v9a:D4, 4v9b:B4, 4v9b:D4, 4v9j:B4, 4v9j:D4, 4v9k:B4, 4v9k:D4, 4v9l:B4, 4v9l:D4, 4v9m:B4, 4v9m:D4, 4v9r:B4, 4v9r:D4, 4v9s:B4, 4v9s:D4, 5vp2:14, 5vp2:24, 5vpo:R4, 5vpo:Y4, 5vpp:R4, 5vpp:Y4, 8vtu:14, 8vtu:24, 8vtv:14, 8vtv:24, 8vtw:14, 8vtw:24, 8vtx:14, 8vtx:24, 8vty:14, 8vty:24, 1vvj:R4, 1vvj:Y4, 1vy4:B4, 1vy4:D4, 1vy5:B4, 1vy5:D4, 1vy6:B4, 1vy6:D4, 1vy7:B4, 1vy7:D4, 4w29:B4, 4w29:D4, 4w2e:4, 4w2f:B4, 4w2f:D4, 4w2g:B4, 4w2g:D4, 4w2h:B4, 4w2h:D4, 4w2i:B4, 4w2i:D4, 4w4g:R4, 4w4g:Y4, 5w4k:14, 5w4k:24, 5wis:14, 5wis:24, 5wit:14, 5wit:24, 4wpo:A4, 4wpo:C4, 4wq1:M8, 4wq1:I5, 4wqf:A4, 4wqf:C4, 4wqr:M8, 4wqr:I5, 4wqu:A4, 4wqu:C4, 4wqy:A4, 4wqy:C4, 4wr6:M8, 4wr6:I5, 4wra:M8, 4wra:I5, 4wro:M8, 4wsd:M8, 4wsd:I5, 4wsm:M8, 4wsm:I5, 4wt1:M8, 4wt1:I5, 4wu1:M8, 4wu1:I5, 4wzd:M8, 4wzd:I5, 4wzo:M8, 4wzo:I5, 6xhv:14, 6xhv:24, 6xhw:14, 6xhw:24, 6xhx:14, 6xhx:24, 6xhy:14, 6xhy:24, 6xqd:14, 6xqd:24, 6xqe:14, 6xqe:24, 4y4o:14, 4y4o:24, 4y4p:14, 4y4p:24, 4ypb:R4, 4yzv:R4, 4yzv:Y4, 4z3s:14, 4z3s:24, 4z8c:14, 4z8c:24, 4zer:14, 4zer:24, 5zlu:w, 4zsn:R4
3 8cd1:Le 68 65 0.3836 0.4118 0.4308 1.91e-13 6spb:1, 7unr:3, 7unu:3, 7unv:3, 7unw:3
4 3j9w:B3 64 64 0.3151 0.3594 0.3594 3.79e-12 6ha1:6, 6ha8:6, 6htq:Z, 5njt:y, 7o5b:6, 8qcq:6, 8qpp:6, 7qv1:6, 7qv2:6, 7qv3:6, 8r55:6, 8s1p:6, 8s1u:6
5 5aka:Z 70 64 0.3973 0.4143 0.4531 5.20e-12 8a3l:4, 7ac7:a, 7acj:a, 7acr:a, 5afi:6, 8akn:4, 8am9:4, 8ana:4, 8ap4:4, 9ax7:4, 8aye:4, 7b5k:5, 3bbx:Z, 8bf7:X, 8bgh:X, 8bhn:X, 8bhp:X, 8bil:X, 8bim:X, 7bl2:b, 7bl3:b, 7bl4:d, 7bl5:b, 7bl6:d, 6bu8:29, 6by1:C0, 6by1:D0, 6c4i:1, 9cg5:4, 9cg6:4, 9cg7:4, 7cpj:6, 7d6z:6, 6dnc:EA, 8eiu:4, 8ekc:3, 8emm:4, 6enf:6, 6enj:6, 6enu:6, 9fbv:4, 8fiz:AV, 8fto:4, 8fzd:3, 8fze:3, 8fzf:3, 8fzg:3, 8fzh:3, 8fzi:3, 8fzj:3, 8g6w:4, 8g6x:4, 8g6y:4, 8g7p:3, 8g7q:3, 8g7r:3, 8g7s:3, 6h4n:6, 6h58:6, 6h58:66, 6hrm:a, 8hsp:4, 8htz:4, 8hu1:4, 8ifb:4, 8ifc:4, 5iqr:a, 2j28:Z, 3j9y:6, 3j9z:LZ, 3ja1:L2, 7k00:4, 7k50:A, 7k51:A, 7k52:A, 7k53:A, 7k54:A, 7k55:A, 5kcs:14, 5kps:1, 5kpv:Z, 5kpw:Z, 5kpx:Z, 5l3p:4, 7lv0:A, 5lza:6, 5lzb:6, 5lzc:6, 5lzd:6, 5lze:6, 5lzf:6, 7m5d:a, 5mdv:a, 5mdw:a, 5mdy:a, 5mdz:a, 5mgp:6, 7n1p:Le, 7n2c:Le, 7n2u:Le, 7n2v:Le, 7n30:Le, 7n31:Le, 7nbu:4, 5np6:4, 7nso:5, 7nsp:5, 7nsq:5, 5nwy:L, 7nwt:a, 7nww:Z, 7o19:BI, 7o1a:BI, 7o1c:BI, 5o2r:6, 6o9j:Z, 7oif:Z, 7oig:Z, 7oii:Z, 7oiz:4, 7oj0:4, 6om6:a, 6ore:a, 6osk:a, 6osq:a, 6ot3:a, 7ot5:Z, 7otc:5, 6ouo:a, 8p16:a, 8p17:a, 8p18:a, 7p3k:4, 8peg:4, 8phj:4, 7pjs:6, 7pjt:6, 7pju:6, 7pjv:6, 7pjw:6, 7pjx:6, 7pjy:6, 7pjz:6, 8pkl:4, 8pva:4, 7q4k:BI, 8q4f:4, 6q97:a, 6q98:a, 6q9a:a, 7qg8:L, 7qgh:L, 7qgn:L, 7qgr:L, 8qk7:a, 8qoa:4, 8r3v:4, 8r6c:4, 8r8m:4, 8rcl:4, 8rcm:4, 8rcs:4, 8rct:4, 8rpy:6, 8rpz:6, 8rq0:6, 8rq2:6, 7s1g:Q, 7s1h:Q, 7s1i:Q, 7s1j:Q, 7s1k:Q, 7sa4:a, 7ssd:A, 7ssl:A, 7sso:A, 7st2:A, 7st6:A, 7st7:A, 8syl:3, 6szs:5, 6tbv:L311, 6tc3:L311, 7tos:L31, 5u9f:29, 5u9g:29, 7ug7:Le, 8upo:g, 8upr:g, 8uql:g, 8uqm:g, 8uqp:g, 8ur0:g, 8urh:g, 8uri:g, 8urx:g, 8ury:g, 5uyk:29, 5uyl:29, 5uym:29, 5uyn:29, 5uyp:29, 5uyq:29, 4v4h:BZ, 4v4h:DZ, 4v4q:BZ, 4v4q:DZ, 4v5b:AZ, 4v5b:CZ, 4v65:BS, 4v66:BS, 4v6k:Ab, 4v6l:Bb, 4v6n:A2, 4v6o:B2, 4v6p:B2, 4v6q:B2, 4v6r:B2, 4v6s:A2, 4v6v:B4, 8vs9:L31, 8vsa:L31, 6vu3:g, 6vyq:g, 6vyr:g, 6vys:g, 6vyt:g, 6vyu:g, 6vyw:g, 6vyx:g, 6vyy:g, 6vyz:g, 6vz2:g, 6vz3:g, 6vz5:g, 6vz7:g, 6vzj:g, 5wdt:6, 5we4:6, 5we6:6, 5wf0:6, 5wfk:6, 5wfs:6, 6wnt:A, 6wnv:A, 6wnw:A, 6x6t:g, 6x7f:g, 6x7k:g, 6x9q:g, 6xdq:g, 6xdr:g, 6xgf:g, 6xii:g, 6xij:g, 6y69:6, 7y7c:4, 7y7d:4, 7y7e:4, 7y7f:4, 7y7g:4, 7y7h:4, 6ysr:6, 6yss:6, 6yst:6, 6ztj:B7, 6zto:B7, 6ztp:B7, 7zta:L311, 6zu1:B7
6 8fmw:Ac 81 81 0.3973 0.3580 0.3580 3.32e-11 8fn2:c
7 6o8z:1 83 79 0.3562 0.3133 0.3291 1.31e-09 6o8w:1, 6o8x:1, 6o8y:1, 6o90:1, 7p7q:3, 7p7r:3, 7p7s:3, 7p7t:3, 7p7u:3
8 9c4g:4 66 66 0.3014 0.3333 0.3333 3.32e-09 8crx:4, 8cvm:4
9 5zeb:2 66 66 0.3425 0.3788 0.3788 3.96e-09 8kab:g, 5o60:g, 7s0s:h, 8why:4, 7xam:g, 8xz3:g, 7y41:g, 5zep:y, 5zet:2
10 6eri:AZ 66 65 0.3288 0.3636 0.3692 1.01e-08 5mmi:0, 5mmm:0, 5x8p:0, 5x8t:0
11 5li0:3 83 36 0.2466 0.2169 0.5000 1.16e-08 7aso:h, 6fxc:AY, 6fxc:BY, 5nd8:3, 5nd9:3, 5ngm:AY, 8p2f:4, 8p2g:4, 8p2h:4, 6s0x:Y, 6s0z:Y, 6s12:Y, 6s13:Y, 5tcu:LF, 8y36:Y, 8y37:Y, 6yef:3
12 7nhn:4 79 36 0.2192 0.2025 0.4444 3.47e-07 8a57:4, 8a5i:4, 8a63:4, 8uu4:3, 8uu5:3, 8uu6:3, 8uu7:3, 8uu8:3, 8uua:3
13 7msc:6 60 66 0.3288 0.4000 0.3636 6.42e-07 7kgb:6, 7msh:6, 7msm:6, 7msz:6, 7mt2:6, 7mt3:6, 7mt7:6, 7sfr:6
14 5myj:B3 79 42 0.2329 0.2152 0.4048 8.01e-07
15 7nhk:3 55 64 0.2740 0.3636 0.3125 3.07e-05
16 6dzi:g 75 38 0.2603 0.2533 0.5000 3.22e-04 6dzp:g, 8fr8:H
17 5o61:g 59 66 0.3151 0.3898 0.3485 3.29e-04 8v9j:3, 8v9k:3, 8v9l:3, 8whx:4, 8wi7:4, 8wib:4
18 7nhl:4 59 34 0.2055 0.2542 0.4412 3.92e-04 7nhm:4
19 8uu9:3 70 35 0.2055 0.2143 0.4286 0.003
20 6i7v:D7 68 28 0.1781 0.1912 0.4643 0.012
21 7p48:Y 70 36 0.2055 0.2143 0.4167 0.015
22 7fd2:A 438 27 0.1781 0.0297 0.4815 0.071 7fd2:I
23 5ini:F 511 47 0.2329 0.0333 0.3617 0.61 5inf:B, 5inf:F, 5ini:A, 5ini:D, 5ini:B, 5ini:C, 5ini:E
24 8h97:A 619 48 0.2055 0.0242 0.3125 0.76
25 4r2w:D 251 39 0.1781 0.0518 0.3333 2.2 7q2w:FFF, 4r2w:A, 4r2w:B, 4r2w:C, 4r2w:E, 4r2w:F, 4r2x:C, 4r2x:D, 4r2x:E, 4r2x:F, 4r2x:A, 4r2x:B, 4yjk:D, 4yjk:F, 4yjk:A
26 4lma:A 318 19 0.1370 0.0314 0.5263 7.1 4lma:B
27 6jw7:A 342 21 0.1096 0.0234 0.3810 8.6 6jw6:A, 6jw6:B, 6jw7:B, 6jw8:A, 6jw8:B
28 3ieu:A 293 33 0.1507 0.0375 0.3333 9.2 3ieu:B
29 5xoq:A 310 31 0.1918 0.0452 0.4516 10.0 5xoq:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218