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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MQGSRKPNIIFIMADDLGWGELGSYGNTFNETPNLDRLSAQGMRFTQAYAAAPVTSPTRASIMTGQYPARVGITDFLPED
EKTDRWLDPTKYVTLNEALSASGYHTGIVGKWHLDTDFKLNKGGPKAHGFNEVIGTESEYIADGDYFFPYSKIASFDKGT
ANEYLTDRQCAEANAFITRNREKPFFLYLSLYSVHTRLEAPVQLVEKYKQKFDQKYGTGKAEQFFGANNVRHESAQRDNP
WLAAMLESIDTGVGGIMKTLRETGLAENTIIVFFSDNGGAGKAGNNAHLRAGKTWLYEGGIREPLIVSWPGKIKGNTVND
NPVTSLDFYPTFLAAAGGKPTGGRLDGHNLMPLLRGGRASGRPLFWHYPSETGKWVNRMSSAVREGNYKLLEFYNNPRLE
LYDLQNDPSESHNLATDRPAETARLKKLLEDWKKEVNAEAPHLAR

The query sequence (length=445) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7stt:A 445 445 1.0000 1.0000 1.0000 0.0 7stu:A, 7stv:A
2 6ust:C 464 474 0.4090 0.3922 0.3840 8.35e-97 6ust:A, 6ust:B, 6ust:D
3 6psm:C 448 462 0.3618 0.3594 0.3485 2.44e-72 6prm:A, 6prm:B, 6prm:C, 6prm:D, 6psm:A, 6psm:B, 6psm:D, 6psm:E, 6psm:F, 6pso:B, 6pso:A
4 7oza:CCC 488 498 0.3798 0.3463 0.3394 7.49e-66 7oza:AAA
5 6uss:A 485 499 0.3573 0.3278 0.3186 3.35e-61 6uss:B
6 7ana:AAA 475 491 0.3326 0.3116 0.3014 4.57e-59 7ana:BBB, 7anb:AAA, 7anb:BBB
7 6b0j:A 452 456 0.3169 0.3119 0.3092 5.41e-58 6b0j:B, 6b0j:C, 6b0k:A, 6b0k:B, 6b0k:C, 6b1v:A, 6b1v:B, 6b1v:C, 6bia:A, 6bia:B, 6bia:C
8 7an1:AAA 483 492 0.3393 0.3126 0.3069 1.12e-54 7oqd:AAA
9 7all:AAA 498 486 0.3056 0.2731 0.2798 6.17e-54
10 1n2l:A 483 461 0.3258 0.3002 0.3145 9.08e-53 1auk:A, 1e1z:P, 1e2s:P, 1e33:P, 1e3c:P, 1n2k:A
11 4fdi:A 494 390 0.2854 0.2571 0.3256 8.09e-51 4fdi:B, 4fdj:A, 4fdj:B
12 1fsu:A 475 492 0.3191 0.2989 0.2886 9.19e-45
13 7oz9:BBB 483 500 0.3146 0.2899 0.2800 2.19e-42 7oz9:AAA
14 4cys:A 534 538 0.3303 0.2753 0.2732 3.50e-38 5aj9:A, 5aj9:B, 4cxk:A, 4cxk:B, 4cxs:A, 4cxs:B, 4cxu:A, 4cxu:B, 4cyr:A, 4cyr:B, 4cys:B, 1hdh:A, 1hdh:B
15 7oz8:AAA 474 471 0.2809 0.2637 0.2654 1.37e-35
16 7p26:AAA 484 499 0.2966 0.2727 0.2645 8.08e-35
17 7oze:AAA 487 518 0.3124 0.2854 0.2683 1.79e-34 7oze:EEE, 7oze:FFF, 7oze:GGG
18 6j66:B 476 501 0.3011 0.2815 0.2675 1.73e-31 6j66:A
19 7lj2:A 507 509 0.2989 0.2623 0.2613 6.34e-31 7lha:A, 7lha:B, 7lj2:B
20 7sno:A 506 512 0.3034 0.2668 0.2637 1.41e-30
21 9fvt:A 519 404 0.2674 0.2293 0.2946 1.66e-30 9fvt:B, 9fvt:C, 9fvt:D
22 6pt4:B 473 479 0.2944 0.2770 0.2735 2.54e-29 6pt4:A, 6pt6:B, 6pt6:A, 6pt9:A, 6pt9:B, 6ptk:A, 6ptk:B, 6ptk:C, 6ptk:D
23 7aj0:A 501 366 0.2292 0.2036 0.2787 6.16e-27 7aj0:B, 7aj0:C, 7aj0:D, 7aj0:E, 7aj0:F
24 7pth:A 517 454 0.2787 0.2398 0.2731 6.26e-27 6fny:A, 6fny:B, 6fny:C, 6fny:D, 6fny:E, 6fny:F, 6fny:G, 6fny:H, 6g5z:A, 6g5z:B, 6g5z:C, 6g5z:D, 6g60:A, 6g60:B, 6g60:C, 6g60:D, 7pth:B, 7pth:C, 7pth:D, 7ptj:A, 7ptj:B, 7ptj:C, 7ptj:D
25 8di0:B 426 435 0.2517 0.2629 0.2575 1.49e-26
26 8eg3:A 554 154 0.1371 0.1101 0.3961 1.18e-25 1p49:A
27 8eg3:A 554 302 0.2067 0.1661 0.3046 1.22e-21 1p49:A
28 6s20:C 480 111 0.1169 0.1083 0.4685 3.06e-24
29 6s20:C 480 301 0.1843 0.1708 0.2724 5.59e-17
30 4upl:A 555 500 0.2876 0.2306 0.2560 3.62e-23 4upl:C
31 6hr5:A 376 429 0.2517 0.2979 0.2611 1.06e-22
32 3b5q:B 467 459 0.2584 0.2463 0.2505 1.39e-21 3b5q:A, 5g2t:A, 5g2t:B, 5g2t:C, 5g2t:D, 5g2u:A
33 4miv:A 484 504 0.2966 0.2727 0.2619 4.21e-21 4mhx:A, 4mhx:B, 4miv:B, 4miv:C, 4miv:D, 4miv:E, 4miv:F, 4miv:G, 4miv:H
34 7p24:AAA 494 172 0.1326 0.1194 0.3430 6.43e-21
35 7p24:AAA 494 190 0.1191 0.1073 0.2789 5.06e-16
36 6hhm:A 459 469 0.2652 0.2571 0.2516 9.51e-21
37 7ozc:AAA 485 109 0.1034 0.0948 0.4220 2.47e-20
38 7ozc:AAA 485 284 0.1685 0.1546 0.2641 1.65e-13
39 5g2v:A 494 259 0.1618 0.1457 0.2780 4.48e-20
40 5g2v:A 494 204 0.1326 0.1194 0.2892 5.59e-19
41 6s21:A 486 397 0.2180 0.1996 0.2443 2.50e-19 6s21:B, 6s21:C
42 4upi:A 548 228 0.1528 0.1241 0.2982 1.96e-17
43 4upi:A 548 111 0.0899 0.0730 0.3604 1.16e-10
44 4uph:A 504 505 0.2854 0.2520 0.2515 2.14e-17 4uph:B, 4uph:C, 4uph:D
45 2w8s:B 513 471 0.2539 0.2203 0.2399 2.42e-16 2w8s:A, 2w8s:C, 2w8s:D
46 2vqr:A 512 495 0.2742 0.2383 0.2465 2.59e-16
47 7ebp:A 526 201 0.1169 0.0989 0.2587 1.37e-15 7ebp:B, 7ebq:A
48 7ebp:A 526 195 0.1348 0.1141 0.3077 1.41e-13 7ebp:B, 7ebq:A
49 5fql:A 507 349 0.1843 0.1617 0.2350 3.35e-11 6ioz:A
50 5xwk:A 530 67 0.0494 0.0415 0.3284 0.34 3q3q:A
51 5xwi:A 503 67 0.0494 0.0437 0.3284 0.36
52 6g4g:C 742 75 0.0472 0.0283 0.2800 0.70
53 6v8q:A 569 69 0.0382 0.0299 0.2464 0.72 6v8q:B, 6vat:A, 6vat:B, 6vat:C, 6vc7:A, 6vc7:B, 6vc7:C, 6vc7:D, 6vc7:E, 6vc7:F, 6vdf:A, 6vdf:C, 6vdf:D
54 6f2t:B 722 75 0.0472 0.0291 0.2800 0.77 6f2t:A, 6f2v:A, 6f2v:B, 6f2y:A, 6f2y:B, 6f30:A, 6f30:B, 6f33:A, 6f33:B
55 6g4g:D 781 75 0.0472 0.0269 0.2800 0.77 6g4g:A
56 6xlp:A 586 83 0.0427 0.0324 0.2289 1.9
57 2ozg:A 388 50 0.0382 0.0438 0.3400 2.4
58 6g4g:B 759 44 0.0360 0.0211 0.3636 2.6
59 6c01:A 819 44 0.0360 0.0195 0.3636 3.8 6c01:B, 6c02:A, 6c02:B
60 5ven:A 382 41 0.0247 0.0288 0.2683 5.2 5ven:B, 5veo:A
61 1avf:J 322 91 0.0517 0.0714 0.2527 6.6 1avf:A
62 6tfo:C 424 89 0.0652 0.0684 0.3258 7.2 6tfd:A, 6tfd:C, 6tfd:B, 6tfo:A, 6tfo:B
63 3vwd:A 196 38 0.0360 0.0816 0.4211 9.1 4b5o:A, 4b5p:A, 4b5p:B, 4gs4:A, 4if5:A, 4pk2:A, 4pk3:A, 4u9y:A, 4u9z:A, 3vwe:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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