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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MPIPNNPGAGENAFDPVFVNDDDGYDLDSFMIPAHYKKYLTKVLVPNGVIKNRIEKLAYDIKKVYNNEEFHILCLLKGSR
GFFTALLKHLSRIHNYSAVETSKPLFGEHYVRVKSYCNDQSTGTLEIVSEDLSCLKGKHVLIVEDIIDTGKTLVKFCEYL
KKFEIKTVAIACLFIKRTPLWNGFKADFVGFSIPDHFVVGYSLDYNEIFRDLDHCCLVNDEGKKKYKAT

The query sequence (length=229) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3ozf:B 234 228 0.9956 0.9744 1.0000 5.21e-170 1cjb:A, 1cjb:B, 1cjb:C, 1cjb:D, 3ozf:A, 3ozf:C, 3ozf:D, 3ozg:A, 3ozg:B, 3ozg:C, 3ozg:D, 7tux:A, 7tux:B, 7tux:C, 7tux:D
2 6bo7:A 220 226 0.7598 0.7909 0.7699 6.50e-130 6bo7:B, 6bo7:C, 6bo7:D, 6bo7:E, 6bo7:F, 6bo7:G, 6bo7:H, 6bo7:I, 6bo7:J, 6bo7:K, 6bo7:L
3 2vfa:B 205 216 0.6157 0.6878 0.6528 4.75e-92 2vfa:A
4 1fsg:A 233 220 0.4934 0.4850 0.5136 1.43e-78 1dbr:A, 1dbr:B, 1dbr:D, 1fsg:C, 1qk3:A, 1qk3:B, 1qk3:C, 1qk3:D, 1qk4:A, 1qk4:B, 1qk4:C, 1qk4:D, 1qk5:A, 1qk5:B
5 1bzy:A 214 213 0.4585 0.4907 0.4930 1.40e-67 6bnj:A, 6bnj:B, 6bnj:C, 6bnj:D, 5brn:A, 5brn:C, 5brn:D, 1bzy:B, 1bzy:C, 1bzy:D, 1d6n:A, 1d6n:B, 3gep:A, 3gep:B, 3ggc:A, 3ggc:B, 3ggj:A, 3ggj:B, 5hia:A, 5hia:B, 5hia:C, 5hia:D, 1hmp:A, 1hmp:B, 4ijq:A, 4ijq:B, 4ijq:C, 4ijq:D, 4rab:A, 4rab:B, 4rab:C, 4rab:D, 4rac:A, 4rac:B, 4rac:C, 4rac:D, 4rad:A, 4rad:B, 4rad:C, 4rad:D, 4rad:E, 4rad:F, 4rad:G, 4rad:H, 4ran:A, 4ran:B, 4ran:C, 4ran:D, 4rao:A, 4rao:B, 4rao:C, 4rao:D, 4raq:A, 4raq:B, 4raq:C, 4raq:D, 7san:A, 7san:B, 7san:C, 7san:D, 8tpv:A, 8tpv:B, 8tpv:C, 8tpv:D, 5w8v:A, 5w8v:B, 5w8v:C, 5w8v:D
6 2jbh:B 213 213 0.4148 0.4460 0.4460 2.71e-57 2jbh:A
7 5brn:B 194 212 0.4017 0.4742 0.4340 2.95e-53 5bsk:A, 5bsk:B, 5bsk:C, 5bsk:D, 4kn6:A, 8tpy:A, 8tpy:B, 8tpy:C, 8tpy:D
8 5ipf:A 201 208 0.3450 0.3930 0.3798 2.73e-40 5ipf:B, 5ipf:C, 5ipf:D
9 5knx:B 176 178 0.2707 0.3523 0.3483 5.08e-23 1g9s:A, 1g9s:B, 1g9t:A, 1g9t:B, 1grv:B, 1grv:A, 1j7j:A, 1j7j:B, 5knr:A, 5knr:B, 5kns:A, 5kns:B, 5knt:A, 5knt:B, 5knu:A, 5knu:B, 5knv:A, 5knv:B, 5knx:A
10 3kb8:A 201 190 0.2751 0.3134 0.3316 1.05e-22 6d9r:A, 6d9r:B, 6d9s:A, 6d9s:B, 3h83:A, 3h83:B, 3kb8:B
11 6igs:B 167 178 0.2533 0.3473 0.3258 5.28e-22 6igs:A, 6igs:C, 6igs:D
12 4qyi:B 171 184 0.2358 0.3158 0.2935 2.04e-17 4qyi:A, 4qyi:C, 4qyi:D, 4qyi:E
13 4pfq:C 184 179 0.2227 0.2772 0.2849 2.03e-16 4pfq:A, 4pfq:B, 4pfq:D, 4pfq:E, 4pfq:F, 4pfq:G, 4pfq:H
14 2geb:A 184 182 0.2227 0.2772 0.2802 6.11e-16 1r3u:A, 1r3u:B, 1yfz:A, 1yfz:B
15 8fx3:B 223 159 0.2009 0.2063 0.2893 4.35e-15 8fwy:A, 8fwy:B, 8fwz:A, 8fwz:B, 8fx0:A, 8fx0:B, 8fx1:A, 8fx1:B, 8fx2:A, 8fx2:B, 8fx3:A
16 3acc:A 166 174 0.2096 0.2892 0.2759 6.37e-14 3acd:A
17 6mxc:C 220 159 0.1965 0.2045 0.2830 1.98e-13 6aqo:A, 6aqo:B, 6aqo:C, 6aqo:D, 6aqo:E, 6aqo:F, 6ar9:A, 6ar9:B, 6ar9:C, 6ar9:D, 6ar9:E, 6ar9:F, 6mxb:A, 6mxb:B, 6mxb:C, 6mxb:D, 6mxb:E, 6mxb:F, 6mxc:A, 6mxc:B, 6mxc:D, 6mxc:E, 6mxc:F, 6mxd:A, 6mxd:B, 6mxd:C, 6mxd:D, 7scr:A, 7scr:C, 7scr:B, 7scr:D, 7scr:E, 7scr:F
18 1p17:B 204 196 0.2314 0.2598 0.2704 2.52e-13 1i0i:A, 1i0i:B, 1i0l:A, 1i0l:B, 1i13:A, 1i13:B, 1i14:A, 1i14:B, 1p17:A, 1p17:C, 1p17:D, 1p18:A, 1p18:B, 1p19:A, 1p19:B, 1p19:C, 1p19:D, 1tc1:A, 1tc1:B, 1tc2:A, 1tc2:B
19 5esw:A 190 166 0.2183 0.2632 0.3012 2.75e-13 5esx:A, 5esx:B
20 1hgx:A 164 179 0.2271 0.3171 0.2905 3.15e-13
21 5kny:B 187 81 0.1354 0.1658 0.3827 3.19e-12 5knp:A, 5knp:B, 5knp:C, 5knp:D, 5knq:A, 5knq:B, 5knq:C, 5knq:D, 5kny:A, 5kny:C, 5kny:D, 4rht:A, 4rht:B, 4rht:C, 4rht:D, 4rhu:A, 4rhu:B, 4rhu:C, 4rhu:D, 4rhu:E, 4rhu:F, 4rhx:A, 4rhx:B, 4rhx:C, 4rhx:D, 4rhy:A, 4rhy:B, 4rhy:C, 4rhy:D
22 7cmj:A 184 176 0.2140 0.2663 0.2784 1.05e-11 1pzm:A, 1pzm:B
23 6aps:A 185 189 0.2271 0.2811 0.2751 7.17e-11 6aps:B, 6apt:A, 6apt:B, 6apu:A, 6apu:B, 6apv:A, 6apv:B, 6apv:C, 6apv:D, 5jsq:A, 5jsq:B, 5jv5:A, 5jv5:B, 5k51:A, 5k51:B, 5k51:C, 5k51:D, 5kam:A, 5kam:C, 5kap:A, 5kap:B, 6mxg:A, 6mxg:B, 7sb7:A, 7sb7:B, 8tr1:A, 8tr1:B, 8tr1:C, 8tr1:D, 8ts4:A, 8ts4:B
24 4zfn:B 177 84 0.1223 0.1582 0.3333 0.004 5bqp:A, 5bqp:B, 5bqp:C, 5bqp:D, 4z1o:A, 4z1o:B, 4zfn:A
25 6asv:C 311 66 0.1048 0.0772 0.3636 0.023 6asv:A, 6asv:B, 4s2u:A, 7xmu:A, 7xmu:F, 7xmu:C, 7xmu:D, 7xmu:B, 7xmu:E, 7xmv:A, 7xmv:F, 7xmv:C, 7xmv:E, 7xmv:B, 7xmv:D, 7xn3:A, 7xn3:E, 7xn3:C, 7xn3:B, 7xn3:D, 7xn3:F
26 4twb:A 278 39 0.0699 0.0576 0.4103 0.14 4twb:B, 4twb:C, 4twb:D, 4twb:E, 4twb:F
27 6fci:A 179 59 0.0742 0.0950 0.2881 0.21 6fch:A, 6fch:B, 6fci:D, 6fci:B, 6fci:C, 6fcl:A, 6fcl:B, 6fd4:B, 6fd4:A, 6fd5:A, 6fd5:B, 6fd6:A, 6fd6:B, 6hgp:A, 6hgq:A, 6hgq:C, 6hgq:D, 6hgq:B, 6hgr:A, 6hgr:B, 6hgs:A, 6hgs:B, 1ore:A, 4x44:A, 4x45:B, 1zn7:A, 1zn7:B, 1zn8:A, 1zn8:B, 1zn9:B
28 3qw4:C 447 38 0.0611 0.0313 0.3684 0.24 3qw4:B
29 5liv:A 397 71 0.0873 0.0504 0.2817 0.29 6f85:A, 6f85:B, 6f88:A, 6f88:B, 6f8a:A, 6f8a:B, 6f8c:A, 6f8c:B, 5liv:B, 5liv:C, 5liv:D
30 4rv4:B 211 39 0.0568 0.0616 0.3333 0.37 4rv4:A, 4rv4:C
31 5kwi:A 283 48 0.0786 0.0636 0.3750 0.39 5kwj:A, 5kwj:B, 5ocj:A, 5ocj:B, 4qe3:A, 4qek:A, 5vns:A
32 1u9z:A 274 49 0.0830 0.0693 0.3878 0.40 1u9z:B, 1u9z:C, 1u9z:D
33 2rnf:A 120 68 0.0830 0.1583 0.2794 0.43 2rnf:B
34 8vz8:A 266 33 0.0568 0.0489 0.3939 0.77 8vz9:A
35 4p86:A 177 166 0.1659 0.2147 0.2289 0.90 4p86:B, 4p86:C, 4p86:D
36 8e73:V2 222 33 0.0611 0.0631 0.4242 1.1 6x89:V2
37 1i5e:A 208 117 0.1135 0.1250 0.2222 1.4 1i5e:B
38 3kw0:B 197 78 0.1135 0.1320 0.3333 1.6 3kw0:A, 3kw0:C, 3kw0:D
39 3mbi:A 287 44 0.0742 0.0592 0.3864 1.9 3lpn:A, 3lpn:B, 3lrt:A, 3lrt:B, 3mbi:C, 3mbi:B, 3mbi:D, 3nag:A, 3nag:B
40 5znq:A 183 70 0.0961 0.1202 0.3143 2.4 5b6h:A, 5y07:A, 5y07:B, 5zc7:A, 5zc7:B, 5zmi:A, 5znq:B, 5zoc:A
41 4qdf:B 357 100 0.1092 0.0700 0.2500 4.1
42 5ief:A 858 25 0.0480 0.0128 0.4400 8.1 5h9o:A, 5h9o:C, 5hjo:A, 5hjo:C, 5hjr:A, 5hjr:C, 5ied:A, 5iee:A, 5ieg:A, 7jty:A, 7jty:C, 7k9n:A, 7k9n:C, 7k9o:A, 7k9o:C, 7k9q:A, 7k9q:C, 7k9t:A, 7k9t:C, 7kad:A, 7kad:C, 7kb6:A, 7kb6:C, 7kb8:A, 7kb8:C, 7kbj:A, 7kbj:C, 7kbr:A, 7kbr:C, 7kry:A, 7kry:C
43 5vog:A 176 42 0.0699 0.0909 0.3810 8.3
44 6fpy:A 600 97 0.1004 0.0383 0.2371 8.3 6fpy:B
45 6nfe:B 299 31 0.0611 0.0468 0.4516 9.7 6nfe:A
46 1ibs:B 299 73 0.0830 0.0635 0.2603 9.9 1dku:A, 1dku:B, 1ibs:A
47 7l08:s 393 188 0.1747 0.1018 0.2128 10.0 8any:s, 7l20:s, 7o9m:s, 7odr:s, 7ods:s, 7odt:s, 8oir:Bi, 8oit:Bi, 8pk0:s, 7po4:s, 7qi4:s, 7qi5:s, 7qi6:s, 8qsj:s, 6vlz:s, 6vmi:s, 6zm5:s, 6zm6:s

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218