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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MPAVSLPPKENALFKRILRCYEHKQYRNGLKFCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSH
VCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHL
LEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKLAVEETKGELLLQLCRL
EDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAWTKYPRGLVPRRLPLNFLSGEKFKECLDKFLRMNFSK
GCPPVFNTLRSLYKDKEKVAIIEELVVGYETSLKSCRLFNPNDDGKEEPPTTLLWVQYYLAQHYDKIGQPSIALEYINTA
IESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDTADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLN
EMQCMWFQTECAQAYKAMNKFGEALKKCHEIERHFIEITDDQFDFHTYCMRKITLRSYVDLLKLEDVLRQHPFYFKAARI
AIEIYLKLHDNPEELIPEKLAKVETPLEEAIKFLTPLKNLVKNKIETHLFAFEIYFRKEKFLLMLQSVKRAFAIDSSHPW
LHECMIRLFNTAVCESKDLSDTVRTVLKQEMNRLTNPKNFNETFLKRNSDSLPHRLSAAKMVYYLDPSSQKRAIELATTL
DESLTNRNLQTCMEVLEALYDGSLGDCKEAAEIYRANCHKLFPYALAFMPP

The query sequence (length=771) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6c95:A 773 773 0.9948 0.9922 0.9922 0.0 6c9m:A, 6c9m:C, 6ppl:B, 6pw9:B
2 9f1b:DB 837 837 0.9715 0.8949 0.8949 0.0 9f1c:DB, 9f1d:DB, 9fpz:B, 9fq0:B
3 4hnx:A 713 669 0.2827 0.3058 0.3259 7.32e-96
4 4xnh:A 786 682 0.2789 0.2735 0.3152 5.73e-94 4hnw:A, 6o07:A, 4xpd:A, 4y49:G
5 6hd7:t 838 617 0.2633 0.2422 0.3290 1.51e-90
6 8chy:A 272 183 0.0597 0.1691 0.2514 3.39e-04 8bu0:A, 8cig:A, 8ckr:A, 8cqp:C, 8cqq:A
7 8chy:A 272 153 0.0532 0.1507 0.2680 0.003 8bu0:A, 8cig:A, 8ckr:A, 8cqp:C, 8cqq:A
8 8chy:A 272 131 0.0441 0.1250 0.2595 1.7 8bu0:A, 8cig:A, 8ckr:A, 8cqp:C, 8cqq:A
9 1na0:B 119 108 0.0363 0.2353 0.2593 0.002 1na3:A, 1na3:B
10 1na0:B 119 86 0.0311 0.2017 0.2791 0.11 1na3:A, 1na3:B
11 1na0:B 119 102 0.0350 0.2269 0.2647 0.46 1na3:A, 1na3:B
12 1na0:B 119 71 0.0272 0.1765 0.2958 9.7 1na3:A, 1na3:B
13 7y4i:A 822 454 0.1284 0.1204 0.2181 0.010 8dti:A, 8dti:B
14 1elw:A 117 86 0.0285 0.1880 0.2558 0.23 1elw:B
15 5lwv:A 711 70 0.0324 0.0352 0.3571 0.36 5bnw:A, 6e37:A, 8fe6:A, 8fe6:C, 8fe6:E, 8fe6:G, 4gyw:A, 4gyy:A, 4gyy:C, 4gz3:A, 5hgv:A, 5nps:A, 6tka:AAA, 5vie:A, 5vie:C, 5vif:A
16 7yeh:A 1020 70 0.0324 0.0245 0.3571 0.45 4ay5:A, 4ay5:B, 4ay5:C, 4ay5:D, 4ay6:A, 4ay6:B, 4ay6:C, 4ay6:D, 5c1d:A, 4cdr:A, 4cdr:B, 4cdr:C, 4cdr:D, 8cm9:A, 8cm9:B, 8cm9:D, 8cm9:C, 8fe7:A, 8fe7:C, 8fe7:E, 8fe7:G, 8fuf:A, 8fuf:C, 8fuf:E, 8fuf:G, 4gyw:C, 4gz3:C, 4gz5:A, 4gz5:B, 4gz5:C, 4gz5:D, 4gz6:A, 4gz6:B, 4gz6:C, 4gz6:D, 5hgv:C, 6ibo:A, 5lvv:A, 6ma1:A, 6ma2:A, 6ma3:A, 6ma4:A, 6ma5:A, 4n39:A, 4n3a:A, 4n3b:A, 4n3c:A, 5npr:A, 3pe3:A, 3pe3:B, 3pe3:C, 3pe3:D, 3pe4:A, 3pe4:C, 6q4m:A, 3tax:A, 3tax:C, 1w3b:A, 4xi9:A, 4xi9:B, 4xi9:C, 4xi9:D, 4xif:A, 4xif:B, 4xif:C, 4xif:D
17 3kd7:A 102 104 0.0337 0.2549 0.2500 0.53 3kd7:B, 3kd7:C, 3kd7:D, 3kd7:E
18 2eb6:A 267 57 0.0220 0.0637 0.2982 0.57 2eb5:A, 2eb5:B, 2eb5:C, 2eb5:D, 2eb5:E, 2eb6:B, 2eb6:C, 2eb6:D, 2eb6:E
19 8qca:B 756 89 0.0324 0.0331 0.2809 1.1
20 5udk:A 461 77 0.0298 0.0499 0.2987 2.6 6c6k:A, 6c6k:B, 5udi:A, 5udj:A, 5udl:A, 5w5h:A, 5w5h:C
21 1mqs:A 588 47 0.0182 0.0238 0.2979 5.4
22 6b2w:A 333 62 0.0208 0.0480 0.2581 6.5 6b2w:B
23 3qdn:A 285 49 0.0220 0.0596 0.3469 7.3 3qou:A
24 5w5i:C 436 64 0.0285 0.0505 0.3438 8.1 5w5i:A
25 5a01:A 681 69 0.0259 0.0294 0.2899 9.2 5a01:B, 5a01:C
26 8ap6:E 383 77 0.0298 0.0601 0.2987 9.7 8ap6:e, 8ap7:E, 8ap7:e, 8apa:e, 8apb:e, 8apc:e, 8apd:e, 8ape:e, 8apf:e, 8apg:e, 8aph:e, 8apj:e, 8apk:e

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218