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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNYPAEPFRIKSVETVSMIPRDERLKKMQEAGYNTFLLNSKDIYIDLLTDSGTNAMSDKQWAGMMMGDEAYAGSENFYHL
ERTVQELFGFKHIVPTHQGRGAENLLSQLAIKPGQYVAGNMYFTTTRYHQEKNGAVFVDIVRDEAHDAGLNIAFKGDIDL
KKLQKLIDEKGAENIAYICLAVTVNLAGGQPVSMANMRAVRELTEAHGIKVFYDATRCVENAYFIKEQEQGFENKSIAEI
VHEMFSYADGCTMSGKKDCLVNIGGFLCMNDDEMFSSAKELVVVYEGMPSYGGLAGRDMEAMAIGLREAMQYEYIEHRVK
QVRYLGDKLKAAGVPIVEPVGGHAVFLDARRFCEHLTQDEFPAQSLAASIYVETGVRSMERGIISAGRNNVTGEHHRPKL
ETVRLTIPRRVYTYAHMDVVADGIIKLYQHKEDIRGLKFIYEPKQLRHFTARFDYI

The query sequence (length=456) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 1c7g:A 456 456 0.9057 0.9057 0.9057 0.0 1c7g:B, 1c7g:C, 1c7g:D, 6dur:A, 6dur:B, 6dvx:A, 6dvx:B, 6dyt:A, 6dyt:B, 6dz5:A, 6dz5:B, 6ecg:A, 2ez2:A, 2ez2:B, 7fjk:A, 7fjk:B, 7fjk:C, 7fjk:D, 6mls:A, 6mls:B, 6mme:A, 6mme:B, 6mo3:A, 6mo3:B, 6mpd:A, 6mpd:B, 6mqq:A, 6mqq:B, 6nv8:A, 6nv8:B, 7tcs:A, 7tcs:B, 7tcs:C, 7tcs:D, 7tdl:A, 7tdl:B, 7tdl:C, 7tdl:D, 2tpl:B, 2vlf:A, 2vlf:B, 2vlh:A, 2vlh:B, 2ycn:A, 2ycn:B, 2ycp:A, 2ycp:B, 2ycp:C, 2ycp:D, 2yct:A, 2yct:B, 2yhk:A, 2yhk:B
2 8v4a:A 466 460 0.4978 0.4871 0.4935 1.11e-157 9bnj:A, 9bnj:B, 9bnj:C, 9bnj:D, 8v2k:A, 8v2k:B, 8v2k:C, 8v2k:D, 8v4a:B, 8v4a:C, 8v4a:D, 8v6p:A, 8v6p:B, 8v6p:C, 8v6p:D, 8v9p:A, 8v9p:B, 8v9p:C, 8v9p:D, 5w19:A, 5w19:B, 5w19:C, 5w19:D
3 8sbg:A 456 456 0.4649 0.4649 0.4649 1.28e-148
4 8sij:A 445 454 0.4496 0.4607 0.4515 1.03e-137 8sij:B
5 2c44:C 468 461 0.4298 0.4188 0.4252 3.55e-133 2c44:A, 2c44:D, 2c44:B, 5d8g:A
6 4w1y:B 433 451 0.4013 0.4226 0.4058 1.08e-115
7 8sl7:D 544 532 0.3509 0.2941 0.3008 1.48e-69 8sl7:A, 8sl7:B, 8sl7:C
8 1jg8:D 344 310 0.1667 0.2209 0.2452 0.003 2fm1:A, 1jg8:A, 1jg8:B, 1jg8:C, 1lw4:D, 1lw4:B, 1lw4:C, 1lw4:A, 1lw5:A, 1lw5:D, 1lw5:C, 1lw5:B, 1m6s:A, 1m6s:D, 1m6s:C, 1m6s:B
9 5tkl:A 350 57 0.0395 0.0514 0.3158 0.27 5tk3:A, 5tkc:A, 5tkn:A, 5tkp:A
10 2po3:A 393 164 0.0811 0.0941 0.2256 0.55 2po3:B
11 3wgc:B 333 64 0.0395 0.0541 0.2812 1.3 3wgb:A, 3wgb:B, 3wgb:C, 3wgb:D, 3wgc:A, 3wgc:C, 3wgc:D
12 8snj:A 370 87 0.0526 0.0649 0.2759 1.7 8sng:A, 8sng:B, 8snj:B, 8snj:C, 8snj:D, 8snj:E, 8snj:F, 8su6:A, 8su6:B
13 6c6r:A 451 83 0.0461 0.0466 0.2530 1.9 6c6n:A, 6c6n:B, 6c6p:A, 6c6p:B, 6c6r:B
14 1o4s:B 384 41 0.0307 0.0365 0.3415 1.9 1o4s:A
15 1c3o:B 379 66 0.0439 0.0528 0.3030 2.4 1c3o:D, 1c3o:F, 1c3o:H, 1ce8:B, 1ce8:D, 1ce8:F
16 1nu5:A 369 35 0.0285 0.0352 0.3714 4.0
17 4wnb:B 125 24 0.0241 0.0880 0.4583 6.6
18 9biw:B 528 177 0.0965 0.0833 0.2486 7.0 9biw:A
19 5y58:B 568 47 0.0285 0.0229 0.2766 8.7 5y58:D, 5y58:F, 5y59:B
20 8ysx:C 200 28 0.0307 0.0700 0.5000 8.7 8ysx:D, 8yvg:C, 8yvg:D
21 1gvr:A 364 37 0.0373 0.0467 0.4595 9.0 2aba:A, 2abb:A, 3f03:K, 6gi7:A, 6gi8:A, 6gi9:A, 6gia:A, 1gvo:A, 1gvq:A, 1gvs:A, 1h50:A, 1h51:A, 1h60:A, 1h61:A, 1h62:A, 1h63:A, 3kft:A, 3kft:B, 5lgx:A, 5lgz:A, 3p62:A, 3p67:A, 3p74:A, 3p7y:A, 3p80:A, 3p81:A, 3p82:A, 3p84:A, 3p8i:A, 3p8j:A, 1vyp:X, 1vyr:A, 1vys:X

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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