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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNYKKNLLLLYDRPREPIFMGKGKSVFDVPDNYLTDRYRPIGPEIQNRFGELAEERIPVRSIALPDLRIPMSLGRQEQFS
LFIPRHRKIAARLIDIFMGMRNIEELQSCAVFARDRINPYLFNYALSVALLHRRDTKNLDLPSVVEVFPDKYVDSRVFEQ
IREEATVVPEGMRMPIVIPKDFTASDLDEEHRLWYFREDIGVNLHHWHWHLVYPFEASNRAIVDKDRRGELFYYMHSQLI
ARYNFERFCNRLQRVKRLNNLREPIAEGYFPKLDSLVASRTWPGRVDNAVIKDLNRELDQIKQDVSDLERWIDRIYEAVH
QGYVVDESGNRIFLDEEKGIDILGNIIESSILSPNRQLYGDMHNVGHVFLSYTHDPDHRHLESFGVMGDVATAMRDPVFY
RWHSFIDDIFQEHKIKLPAYTKSQLTYEGISVTGIIVQSEGAPVNTLHTYWQQSDVDLSRGMDFVPRGNVFARFTHLQHA
PFQYVIQIDNTSDAQRMGFVRIFMAPKNDERGQPMLFRDQRLFMVEMDKFLVALRPGANRIRRRSNESTVTIPFERTFRC
GCGWPAHMLVPKGLPEGFPADLFVMVSNYEDDRVVQDLVGTCNDYCGVRDRLYPDRKAMGFPFDRLARTGVDRLSNFVTP
NMAIQSVNVIHIDKTVPRT

The query sequence (length=659) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8jib:E 661 661 1.0000 0.9970 0.9970 0.0 8ji8:A, 8ji8:B, 8ji8:C, 8ji8:D, 8jib:A, 8jib:B, 8jib:C, 8jib:D, 8jib:F, 8jib:G, 8jib:H, 8jib:I, 8jib:J, 8jib:K, 8jib:L
2 3hhs:B 656 658 0.5781 0.5808 0.5790 0.0
3 3hhs:A 669 664 0.4962 0.4888 0.4925 0.0
4 4yzw:B 682 675 0.4871 0.4707 0.4756 0.0 4yzw:A
5 1nol:A 607 583 0.3505 0.3806 0.3962 1.07e-143 1ll1:A, 1lla:A
6 1oxy:A 573 578 0.3429 0.3944 0.3910 9.66e-140
7 3wky:A 655 606 0.3156 0.3176 0.3432 1.25e-105 3wky:B
8 1hcy:A 644 615 0.3005 0.3075 0.3220 1.05e-93
9 6l8s:A 650 665 0.3096 0.3138 0.3068 7.44e-93 1hc1:A, 1hc1:B, 1hc1:C, 1hc1:D, 1hc1:E, 1hc1:F, 6l8s:B, 6l8s:C
10 3gwj:D 674 629 0.2443 0.2389 0.2560 3.68e-47 3gwj:A, 3gwj:F, 3gwj:B, 3gwj:E, 3gwj:C
11 8can:A 683 625 0.2625 0.2533 0.2768 1.58e-46 8can:B, 8can:C, 8can:D, 8can:E, 8can:F
12 8ca9:A 680 629 0.2428 0.2353 0.2544 2.74e-45 8ca9:B, 8ca9:C, 8po9:D, 8po9:A, 8po9:B, 8po9:C, 8po9:E, 8po9:F
13 8cad:A 636 613 0.2276 0.2358 0.2447 1.35e-41 8cad:B, 8cad:C, 8cad:D, 8cad:E, 8cad:F
14 8ca9:D 678 627 0.2261 0.2198 0.2376 1.53e-39 8ca9:E, 8ca9:F
15 5yy2:A 569 544 0.1882 0.2179 0.2279 2.08e-24
16 8as8:A 597 115 0.0501 0.0553 0.2870 0.15 8as8:B, 8bfn:A, 8bfn:B, 8bfn:F, 8bfn:G
17 6iig:A 495 99 0.0288 0.0384 0.1919 0.16 6cfg:B, 6ijt:A, 6in5:A, 6vmz:B, 6vmz:D, 6vmz:F, 5z88:A
18 8q72:A 750 111 0.0486 0.0427 0.2883 0.21 8q72:B, 8q72:F, 8q72:G
19 5awm:A 345 177 0.0607 0.1159 0.2260 0.71
20 4o6z:A 448 40 0.0212 0.0312 0.3500 2.6 4o6z:B, 4o6z:C
21 9ey8:DA 450 51 0.0228 0.0333 0.2941 3.1 9ey5:A, 9ey6:A, 9ey7:A, 9ey8:AA, 9ey8:BA, 9ey8:CA, 5m8l:A, 5m8l:C, 5m8l:B, 5m8l:D, 5m8m:A, 5m8m:B, 5m8m:C, 5m8m:D, 5m8n:A, 5m8n:C, 5m8n:D, 5m8n:B, 5m8o:B, 5m8o:C, 5m8o:A, 5m8o:D, 5m8p:A, 5m8p:B, 5m8p:C, 5m8p:D, 5m8q:A, 5m8q:C, 5m8q:D, 5m8q:B, 5m8r:A, 5m8r:B, 5m8r:C, 5m8r:D, 5m8s:A, 5m8s:B, 5m8s:D, 5m8s:C, 5m8t:A, 5m8t:B, 5m8t:C, 5m8t:D
22 6n41:A 483 99 0.0288 0.0393 0.1919 4.2 6cf7:B, 7jpd:D, 8sd2:B, 8sd4:B, 7uyi:E, 8vql:B, 8vqm:B, 8vqn:B, 8vqq:B, 5w5s:B, 5w5u:B, 5w6i:B, 5w6r:B, 5w6r:D, 5w6r:F, 5w6r:H, 5w6t:B, 5w6u:B, 6wcr:B, 2wrg:M
23 5ere:A 540 110 0.0455 0.0556 0.2727 5.4
24 7arc:U 84 57 0.0228 0.1786 0.2632 5.4 7ard:U
25 8fve:B 538 81 0.0364 0.0446 0.2963 6.6 2ad5:A, 2ad5:B, 8fv6:AAA, 8fv6:BBB, 8fv7:AAA, 8fv7:BBB, 8fv8:AAA, 8fv8:BBB, 8fv9:AAA, 8fv9:BBB, 8fva:AAA, 8fva:BBB, 8fvb:AAA, 8fvb:BBB, 8fvc:AAA, 8fvc:BBB, 8fvd:A, 8fvd:B, 8fve:A, 8i9o:A, 8i9o:B, 8i9o:D, 8i9o:C, 1s1m:A, 1s1m:B, 8sbr:A, 8sbr:B, 5tkv:A, 5tkv:B, 5u3c:A, 5u3c:B, 5u3c:C, 5u3c:D, 5u6r:A, 5u6r:B, 5u6r:C, 5u6r:D
26 2v25:A 231 61 0.0273 0.0779 0.2951 7.3 2v25:B
27 7a5f:K3 177 90 0.0364 0.1356 0.2667 7.6 7a5g:K3, 7a5h:K, 7a5i:K3, 7a5j:K, 7a5k:K3, 5aj4:BN, 8any:K, 4ce4:N, 6gaw:BN, 6gb2:BN, 6i9r:K, 3j7y:K, 3j9m:K, 8k2a:LM, 8k2b:LM, 7l08:K, 7l20:K, 7nqh:BN, 7nql:BN, 7nsh:BN, 7nsi:BN, 7nsj:BN, 6nu2:K, 6nu3:K, 7o9k:K, 7o9m:K, 7odr:K, 7ods:K, 7odt:K, 7of0:K, 7of2:K, 7of3:K, 7of4:K, 7of5:K, 7of6:K, 7of7:K, 7og4:XK, 7oi6:K, 7oi7:K, 7oi8:K, 7oi9:K, 7oia:K, 7oib:K, 7oic:K, 7oid:K, 7oie:K, 8oin:BR, 8oiq:BR, 8oir:BR, 8oit:BR, 5ool:K, 5oom:K, 7pd3:K, 8pk0:K, 7po4:K, 7qh6:K, 7qh7:K, 7qi4:K, 7qi5:K, 7qi6:K, 8qsj:K, 8qu1:K, 8qu5:K, 4v19:N, 6vlz:K, 6vmi:K, 8xt0:LM, 8xt1:LM, 8xt2:LM, 8xt3:LM, 6ydp:BN, 6ydw:BN, 6zm5:K, 6zm6:K, 6zs9:XK, 6zsa:XK, 6zsb:XK, 6zsc:XK, 6zsd:XK, 6zse:XK, 6zsg:XK
28 6hft:A 312 36 0.0197 0.0417 0.3611 9.3
29 5gvk:A 442 40 0.0212 0.0317 0.3500 9.9 5gvk:B, 5gvk:C, 5gvl:A, 5gvl:B, 5gvl:C, 5gvm:A, 5gvm:B, 5gvm:C, 5gvn:A, 5gvn:B, 5gvn:C, 5gvp:A, 5gvp:B, 5gvp:C, 4oyt:A, 4oyt:B, 4oyt:C, 4pff:A, 4pff:B, 4pff:C, 4pfn:A, 4pfn:B, 4pfn:C, 4tmr:A, 4tmr:B, 4tmr:C, 4tn4:A, 4tn4:B, 4tn4:C, 5xmp:A, 5xmp:B, 5xmp:C, 5xmq:A, 5xmq:B, 5xmq:C, 5xmr:A, 5xmr:B, 5xmr:C, 5xms:A, 5xms:B, 5xms:C, 5xmt:A, 5xmt:B, 5xmt:C, 5xmu:A, 5xmu:B, 5xmu:C, 5xmv:A, 5xmv:B, 5xmv:C, 5yfy:A, 5yfy:B, 5yfy:C, 5yfz:A, 5yfz:B, 5yfz:C, 5yg0:A, 5yg0:B, 5yg0:C, 5yg1:A, 5yg1:B, 5yg1:C, 5yg2:A, 5yg2:B, 5yg2:C, 5yg3:A, 5yg3:B, 5yg3:C, 5yg4:A, 5yg4:B, 5yg4:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218