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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNVTITSPFWKRRRDQIVESVIPYQWGVMNDEIDTTVPDDPAGLADSKSHAVANLKVAAGELDDEFHGMVFQDSDVYKWL
EEAAYALAYHPDPELKALCDRTVDLIARAQQSDGYLDTPYQIKSGVWADRPRFSLIQQSHEMYVMGHYIEAAVAYHQVTG
NEQALEVAKKMADCLDANFGPEEGKIHGADGHPEIELALAKLYEETGEKRYLTLSQYLIDVRGQDPQFYAKQLKAMNGDN
IFHDLGFYKPTYFQAAEPVRDQQTADGHAVRVGYLCTGVAHVGRLLGDQGLIDTAKRFWKNIVTRRMYVTGAIGSTHVGE
SFTYDYDLPNDTMYGETCASVAMSMFAQQMLDLEPKGEYADVLEKELFNGSIAGISLDGKQYYYVNALETTPDGLDNPDR
HHVLSHRVDWFGCACCPANIARLIASVDRYIYTERDGGKTVLSHQFIANTAEFASGLTVEQRSNFPWDGHVEYTVSLPAS
ATDSSVRFGLRIPGWSRGSYTLTVNGKPAVGSLEDGFVYLVVNAGDTLEIALELDMSVKFVRANSRVRSDAGQVAVMRGP
LVYCAEQVDNPGDLWNYRLADGVTGADAAVAFQADLLGGVDTVDLPAVREHADEDDAPLYVDADEPRAGEPATLRLVPYY
SWANREIGEMRVFQRRA

The query sequence (length=657) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3wrg:A 658 658 0.9985 0.9970 0.9970 0.0 7bzl:A, 7dif:A, 7exu:A, 7exv:A, 7exw:A, 8qf2:A, 3wkx:A, 3wre:A
2 6ex6:A 634 683 0.3425 0.3549 0.3294 2.32e-109 6ex6:B
3 1jqg:A 409 90 0.0396 0.0636 0.2889 0.17
4 7omd:B 310 111 0.0411 0.0871 0.2432 1.2 7omd:A, 7omo:A, 7omr:A, 2psj:A, 2psj:B, 6yn2:A, 6yn2:B
5 7b1s:D 593 88 0.0411 0.0455 0.3068 1.3 7b1s:A, 7b2c:A, 7b2c:D
6 6lum:A 539 123 0.0441 0.0538 0.2358 1.8 6lum:J, 6lum:P
7 4gpc:A 212 98 0.0472 0.1462 0.3163 2.6 4gpc:B, 4gpc:C, 4gpf:A, 4gpf:B, 4gpf:C, 4gph:A, 4gph:B, 4gph:C, 3i8r:A, 3i8r:B, 3i8r:C, 1iw0:B, 1iw0:A, 1iw0:C, 1iw1:A, 1iw1:B, 1iw1:C, 3moo:A, 3moo:B, 1v8x:A, 1v8x:B, 1v8x:C, 1wnv:A, 1wnv:B, 1wnv:C, 1wnw:A, 1wnw:B, 1wnw:C, 1wnx:A, 1wnx:B, 1wzd:A, 1wzd:B, 1wzf:A, 1wzf:B, 1wzg:A, 1wzg:B, 2z68:A, 2z68:B
8 2i76:A 247 115 0.0426 0.1134 0.2435 3.1 2i76:B
9 4rti:A 175 32 0.0213 0.0800 0.4375 5.5
10 2e2l:A 317 45 0.0244 0.0505 0.3556 7.6 2e2l:C, 2e2l:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218