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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNLRAAGPGWLFCPADRPERFAKAAAAADVVILDLEDGVAEAQKPAARNALRDTPLDPERTVVRINAGGTADQARDLEAL
AGTAYTTVMLPKAESAAQVIELAPRDVIALVETARGAVCAAEIAAADPTVGMMWGAEDLIATLGGSSSRRADGAYRDVAR
HVRSTILLAASAFGRLALDAVHLDILDVEGLQEEARDAAAVGFDVTVCIHPSQIPVVRKAYRPSHEKLAWARRVLAASRS
ERGAFAFEGQMVDSPVLTHAETMLRRA

The query sequence (length=267) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6aq4:B 268 267 1.0000 0.9963 1.0000 0.0 6aq4:A, 6aq4:C, 6arb:A, 6arb:B, 6arb:C, 6as5:A, 6as5:C, 6as5:B, 6chu:A, 6cj3:A, 6cj4:A, 1u5v:A, 1z6k:A
2 5vxc:A 301 287 0.3633 0.3223 0.3380 6.02e-41 5vxo:A, 5vxo:B, 5vxo:C
3 8khl:A 275 266 0.4232 0.4109 0.4248 5.85e-35 8khl:B, 8khl:C, 8wco:A, 8wco:C, 8wco:B
4 4l9y:C 316 296 0.3633 0.3070 0.3277 3.28e-23 4l9y:A, 4l9y:B, 4l9y:D, 4l9y:E, 4l9y:F, 4l9z:A, 4l9z:B, 4l9z:C, 4l9z:D, 4l9z:E, 4l9z:F
5 5ugr:A 323 301 0.3184 0.2632 0.2824 5.99e-19
6 1sgj:A 231 228 0.2772 0.3203 0.3246 3.55e-16 1sgj:B, 1sgj:C
7 4l80:C 347 286 0.2697 0.2075 0.2517 2.26e-13 6kkh:C, 6kkh:F, 6kkh:I, 6kkh:L, 4l80:A, 4l80:B, 4l80:D, 4l80:F, 4l80:E
8 3r4i:A 321 265 0.2397 0.1994 0.2415 3.16e-04 3r4i:B, 3r4i:C, 3r4i:D, 3r4i:E, 3r4i:F
9 8cou:A 413 46 0.0824 0.0533 0.4783 0.25 4b7v:A, 4b7v:B, 8cn2:B, 8cn2:A, 8cn4:A, 8cn4:B, 8cn5:B, 8cn5:A, 8cn7:A, 8cn7:B, 8cne:A, 8cne:B, 8cng:A, 8cng:B, 8cou:B, 8cov:A, 8cov:B, 4jb6:A, 4jb6:B, 4jpf:A, 7oc0:A, 7oc0:B, 7oc1:A, 7oc1:B, 8pd1:A, 8pd1:B, 8pfz:A, 8pfz:B, 8pj0:A, 8pj0:B, 8pj0:C, 8pj0:D, 8qer:A, 8qer:B, 8qm1:A, 8qm1:B, 8r0i:A, 8r0i:B, 8r1v:A, 8r1v:B, 5sn5:A, 5sn6:A, 5sn7:A, 5sn7:B, 5sn8:A, 5sn9:A, 5sna:B, 5snb:A, 5snc:A, 5snd:A, 5snd:B, 5sne:A, 5sne:B, 5snf:A, 5sng:A, 5snh:A, 5snh:B, 5sni:A, 5sni:B, 5snj:A, 5snj:B, 5snk:A, 5snl:B, 5snm:A, 5snn:A, 5snn:B, 5sno:A, 5sno:B, 5snp:A, 5snp:B, 5snq:B, 5sns:B, 5snt:A, 5snu:A, 5snu:B, 5snv:A, 5snv:B, 5snw:A, 5snx:A, 5snx:B, 5sny:A, 5snz:B, 5so0:A, 5so0:B, 5so1:A, 5so1:B, 5so2:A, 5so2:B, 5so3:A, 5so4:A, 5so4:B, 5so5:A, 5so5:B, 5so6:A, 5so7:A, 5so7:B, 5so8:A, 5so8:B, 5so9:B, 5soa:A, 5sob:A, 5sob:B, 5soc:A, 5soc:B, 5sod:A, 5soe:A, 5soe:B, 5sof:A, 5sog:A, 5sog:B, 5soh:A
10 3oyz:A 376 53 0.0712 0.0505 0.3585 0.70
11 5tao:A 356 53 0.0712 0.0534 0.3585 0.77 3oyx:A, 3pug:A
12 4cnj:A 391 113 0.1124 0.0767 0.2655 1.2 4cnj:B, 4cnj:C, 4cnj:D, 4cnk:A, 4cnk:B
13 7ane:t 226 62 0.0749 0.0885 0.3226 1.4
14 6f45:B 72 55 0.0562 0.2083 0.2727 6.6 6f45:A
15 2h0v:A 335 55 0.0824 0.0657 0.4000 7.1 2h0v:B, 8hfb:A, 8hfb:B, 1y3t:A, 1y3t:B
16 6hac:A 342 70 0.0824 0.0643 0.3143 8.2 6hae:A, 6hae:K, 6hav:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218