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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNLPEDAVLVDTRPRPAYEAGHLPGARHLDLSAPKLRLREEAELKALEGGLTELFQTLGLRSPVVLYDEGLTSRLCRTAF
FLGLGGLEVQLWTEGWEPYATEKEEPKPERTEVVAKLRRDWLLTADEAARHPLLLDVRSPEEFQGKVHPPCCPRGGRIPG
SKNAPLELFLSPEGLLERLGLQPGQEVGVYCHSGARSAVAFFVLRSLGVRARNYLGSMHEWLQEGLPTEP

The query sequence (length=230) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2eg3:A 230 230 1.0000 1.0000 1.0000 3.18e-166 2eg3:B, 2eg4:A, 2eg4:B
2 1h4k:X 271 240 0.3130 0.2657 0.3000 6.64e-15
3 1qxn:A 137 96 0.1478 0.2482 0.3542 2.58e-08 1qxn:B
4 3tp9:A 473 226 0.2565 0.1247 0.2611 2.88e-06 3tp9:B
5 6ktv:A 431 267 0.3130 0.1671 0.2697 5.17e-05 6h98:A, 6h99:A, 6h9a:A, 6ktw:A, 6ktx:A, 6ktz:A, 6ku1:A, 6ku1:B, 6ku2:A, 6ku2:E, 6kvw:A, 6kvw:B, 6kvy:A, 6kvz:A, 6kw0:A, 6kw0:B
6 5wqk:A 293 179 0.2087 0.1638 0.2682 2.67e-04 5wqj:A, 5wqj:B, 5wqk:B
7 4jgt:A 280 179 0.2130 0.1750 0.2737 0.003 4jgt:B, 4jgt:C
8 8a56:B 539 99 0.1348 0.0575 0.3131 0.004 8a56:A
9 3nt6:A 565 97 0.1261 0.0513 0.2990 0.006 3nt6:B, 3nta:A, 3nta:B, 3ntd:A, 3ntd:B, 4ocg:A, 4ocg:B
10 5ve5:A 350 118 0.1565 0.1029 0.3051 0.023 5ve3:B, 5ve3:A, 5ve4:A, 5ve4:B, 5ve4:C, 5ve5:B, 5ve5:C
11 6yub:A 423 111 0.1348 0.0733 0.2793 0.032 6yub:B, 6yuc:D, 6z6s:DDD
12 1orb:A 293 178 0.1913 0.1502 0.2472 0.085
13 8h4q:N 488 118 0.1304 0.0615 0.2542 0.11 8h4h:N, 8h4h:A, 8h4q:A
14 6mxv:B 251 102 0.1217 0.1116 0.2745 0.52
15 7elh:B 1264 50 0.0739 0.0134 0.3400 1.1 1mwh:A, 1n1h:A, 1n35:A, 1n38:A, 1uon:A, 7yed:R, 7yfe:R
16 1yt8:A 525 40 0.0696 0.0305 0.4000 1.1
17 1yt8:A 525 55 0.0870 0.0381 0.3636 2.2
18 5fwt:A 293 39 0.0565 0.0444 0.3333 1.5 5fws:A, 5fww:B
19 7b0n:G 694 100 0.1130 0.0375 0.2600 3.0 6gcs:A, 7o6y:A, 7o71:A, 6rfq:A, 6rfr:A, 6rfs:A, 6y79:A, 6yj4:G
20 8ih7:A 340 32 0.0609 0.0412 0.4375 4.6 8ih7:C
21 4ub9:A 467 56 0.0739 0.0364 0.3036 5.8 4ub9:B, 4ub9:C, 4ub9:D, 4ub9:E, 4ub9:F, 4ub9:G, 4wgx:A
22 6kd5:B 238 64 0.0652 0.0630 0.2344 7.4
23 2eih:A 343 53 0.0609 0.0408 0.2642 9.1 2eih:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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