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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNIQAIDTRHGTANQHSFSNGNCLPYTGVPFGMNFYAPQTTDQKGSWWFHPEDRTFQGYRVTHQPSPWMGDFSHLLMTPV
SGSLSELSLFHAQSSYRPEESLFSPVEINLTQLRYQITSQLIPSMYGGILTIDYQQKDNHLLLTLPGRYQVKQLDDHQVA
VKVINYSGCEDPDFSFYFVLHFEQPLTKWFAPSSGEDGKILLSFGNIAQQVVHFSSSFISEKQAQLNLAREISLRSTEML
QQGIADWHNYFDRLKVTHENPEHTKTFYHTLYRTFLFPQTFYELDENQQPIHYDTFSQTVRPGVLYTNNGFWDTYKTVYP
LFSLIAQEKYEEMLEGFLNSYNETGFLPKWLSPDERGLMPGTLIDAVIADAAVKKIRPDLMPQFLEAMKKGATQQSEREN
YGRQGTLDYLKYGYVPSTYHESVNHTLDYAYSDFCISQVAKTLNDSETATFYRQQALNYQQLFNPETGFMQAKDTEGNFR
PDFLDIRWGKDYAQGSAWQSSFAVYQDFAGLIKLYGSELAFEKKLIQLCNQAPNFNVEGYGFEIHEMSEMAAIDFGQLAI
SNQPSFHYPFLFSYIGKPEMAQPLLKQLMQTFDASPTGYPGDEDNGSMSAWYIFNSLGFYPVTPGAGEYVIGMPLVQTAE
VKLSNGKQLTIQTSPNKVQQQFIHEIQLNQEKHTAPYFTHQELLNGGTLDYQLGIVPNPQTTAERPFSLSTE

The query sequence (length=712) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6dwo:A 712 712 0.9958 0.9958 0.9958 0.0 6dwo:B, 6dwo:C, 6dwo:D, 7fe1:A, 7fe1:B, 7fe1:C, 7fe1:D, 7fe2:A, 7fe2:B, 7fe2:C, 7fe2:D
2 5swi:B 693 702 0.4593 0.4719 0.4658 0.0 5swi:A, 5swi:C, 5swi:D
3 2ww2:B 737 737 0.3483 0.3365 0.3365 1.66e-143
4 2wvz:B 742 736 0.3301 0.3167 0.3193 6.21e-133 2wvx:A, 2wvx:B, 2wvx:C, 2wvx:D, 2wvz:A, 2wvz:C, 2wvz:D, 2ww0:A, 2ww0:B, 2ww0:C, 2ww0:D, 2ww0:E, 2ww0:F, 2ww0:G, 2ww0:H, 2ww1:A, 2ww1:B, 2ww1:C, 2ww1:D, 2ww3:A, 2ww3:B, 2ww3:C, 2ww3:D, 2ww3:E, 2ww3:F, 2wzs:A, 2wzs:B, 2wzs:C, 2wzs:D, 2wzs:E, 2wzs:F, 2wzs:G, 2wzs:H
5 7nsn:A 1371 761 0.3020 0.1568 0.2825 2.11e-91 7nsn:B
6 7zgm:A 702 721 0.2879 0.2920 0.2843 4.38e-69
7 6f8z:A 715 726 0.2612 0.2601 0.2562 7.68e-65 6f8z:B, 6f8z:C, 6f90:A, 6f90:B, 6f90:C
8 6f92:A 760 729 0.2711 0.2539 0.2647 2.85e-62 6f91:A, 6f91:B, 6f91:C, 6f91:D, 6f91:E, 6f91:F, 6f91:G, 6f91:H, 6f92:B, 6f92:C, 6f92:D
9 4aq0:A 765 588 0.1685 0.1569 0.2041 4.30e-11 4aq0:B, 2xsg:A, 2xsg:B
10 2j0v:B 184 65 0.0281 0.1087 0.3077 4.0 2j0v:A, 2j0v:C, 2j0v:D
11 8uw8:A 738 51 0.0267 0.0257 0.3725 5.0
12 8sfo:A 1240 176 0.0590 0.0339 0.2386 5.4 8sfi:A, 8sfp:A, 8sfq:A, 8sfr:A
13 4u5x:A 178 88 0.0351 0.1404 0.2841 6.2
14 2why:A 283 64 0.0267 0.0671 0.2969 7.7 2xuz:A, 2xv1:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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