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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNIMDNEIDTKCINEIRMLSAELPLEAKSGHQGAPIGCAPIAHILWSYVMNYYNEDTKWINRDRFILSNGHASALLYTML
YLTEQGLSMEDLKSFRQFGSLTPGHPENHITKGVEVTTGPLGQGASNAVGMAIAAHNLADKYNTEEHKIFDNYVYAICGD
GCMQEGVFCEAASLAGHLGLGRLILLYDDNKITIDGNTDLSFTENIEKKFEALNWEVRRVEDGNKDYKKILHEIEQGKKN
LQQPTLIIVRTACGFGTKVEGTCKSHGLALNDEDLKNAKSFFGLDPQKKFHISDEVKEFYKNVIQKKKENYIKWKNMFDD
FSLKYPQVSQEIIRRFQNDLPNNWKDALPKYTPKDAPGATRNLSGIVLNSINKIFPELIGGSADLSESNCTSLKEENDIK
KNSYGNKYIRFGVREHGMVAITNGLYAYGGFKPYCGTFLNFYTYAFGALRLAALSNHHILCIATHDSVELGEDGPTHQPI
EVLSLLRSTPNLNIIRPADGNEVSGAYLSHFSNPHTPTVIALCRNKVPHLNNTQPEQVLKGAYILEDFDTSNNPKVILTG
SGSELHLCFEAKEILKNQHQLNVRIVSFPSWTLFKKQPEDYQYSVMMHNHPNLPRFYIEPASTHGFDTYFNVYIGINQFG
YSAPKNKIWEHLGFTPENIVQKVLAFMKNKLKENLY

The query sequence (length=676) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8r3q:D 676 676 1.0000 1.0000 1.0000 0.0 8r3q:B, 8r3q:A, 8r3q:C
2 1ay0:A 678 674 0.4852 0.4838 0.4866 0.0 1ay0:B, 1gpu:A, 1gpu:B, 1ngs:A, 1ngs:B, 1tka:A, 1tka:B, 1tkb:A, 1tkb:B, 1tkc:A, 1tkc:B, 1trk:A, 1trk:B
3 5hje:A 676 674 0.4512 0.4512 0.4525 0.0 5hyv:A, 5i51:A, 5i5e:A, 5i5g:A, 5xps:A, 5xqa:A, 5xqk:A, 5xrv:A, 5xry:A, 5xs6:A, 5xsa:A, 5xsb:A, 5xsm:A, 5xt0:A, 5xt4:A, 5xtl:A, 5xtv:A, 5xtx:A, 5xu2:A, 5xu9:A, 5xuf:A, 5xvt:A
4 8ci0:AAA 666 667 0.4393 0.4459 0.4453 0.0 8ci0:BBB, 8ci0:CCC, 1itz:A, 1itz:B, 1itz:C
5 1r9j:B 671 653 0.4127 0.4158 0.4273 0.0 1r9j:A
6 5nd5:A 669 674 0.4334 0.4380 0.4347 0.0 5nd5:B
7 3m49:A 665 664 0.4275 0.4346 0.4352 0.0 3hyl:A, 3hyl:B, 3m49:B
8 8cip:A 665 671 0.4201 0.4271 0.4232 0.0 8cip:B, 8cip:C, 8cip:D
9 7wrr:A 650 662 0.4112 0.4277 0.4199 0.0 7wrr:B, 7wrr:C, 7wrr:D, 7wrt:A, 7wrt:B, 7wrt:C, 7wrt:D
10 8r3p:A 672 681 0.4246 0.4271 0.4214 1.35e-178 8r3p:B, 8r3p:C, 8r3p:D
11 8r3s:A 663 671 0.4098 0.4178 0.4128 1.95e-172 8r3s:B, 8r3s:C, 8r3s:D, 8r3s:E, 8r3s:F, 8r3s:G, 8r3s:H, 8r3s:I, 8r3s:J
12 4c7x:A 662 671 0.4157 0.4245 0.4188 4.75e-170
13 8r3o:B 667 676 0.4157 0.4213 0.4157 4.64e-163 8r3o:A, 8r3o:C, 8r3o:D
14 5vrb:B 646 662 0.3979 0.4164 0.4063 2.75e-159 5vrb:D
15 5hht:B 667 667 0.3905 0.3958 0.3958 1.83e-153 5hht:A, 1qgd:A, 1qgd:B, 2r5n:A, 2r5n:B, 2r8o:A, 2r8o:B, 2r8p:A, 2r8p:B, 6rjc:A, 6rjc:B, 6tj8:A, 6tj8:B, 6tj9:A, 6tj9:B, 8wa7:A, 8wa7:B
16 8qmf:A 678 676 0.3935 0.3923 0.3935 4.64e-152 8qmf:B
17 5vrb:A 627 663 0.3935 0.4242 0.4012 2.93e-149 5vrb:C
18 3rim:A 694 675 0.3698 0.3602 0.3704 1.72e-147 3rim:C, 3rim:B, 3rim:D
19 8r3r:A 658 671 0.3861 0.3967 0.3890 5.98e-147 8r3r:B, 8r3r:C, 8r3r:D
20 4xeu:A 632 661 0.3802 0.4066 0.3888 1.66e-146
21 3upt:A 671 674 0.3772 0.3800 0.3783 1.47e-138 3upt:B
22 3m34:A 632 663 0.3861 0.4130 0.3937 3.74e-137 3m6l:A, 3m7i:A
23 6rjb:B 622 583 0.2441 0.2653 0.2830 2.13e-45 6ha3:A, 6had:A, 4kxu:A, 4kxv:A, 4kxw:A, 4kxx:A, 4kxy:A, 4kxy:B, 3mos:A, 3ooy:A, 3ooy:B, 6rjb:A, 8wa8:A, 8wa9:A, 8wa9:B, 8waa:A, 8waa:B
24 6yak:AAA 282 283 0.1464 0.3511 0.3498 2.96e-36 6yak:CCC
25 6yak:DDD 311 320 0.1198 0.2605 0.2531 1.69e-14 6yak:BBB
26 8a45:F 573 114 0.0473 0.0558 0.2807 2.41e-05 8a29:A, 8a29:B, 8a29:C, 8a29:D, 8a29:E, 8a29:F, 8a45:A, 8a45:B, 8a45:C, 8a45:D, 8a45:E, 8a4d:A, 8a4d:B, 8a4d:C, 8a4d:D, 8a4d:E, 8a4d:F, 8a5k:A, 8a5k:B, 8a5k:C, 8a5k:D, 8a5k:E, 8a5k:F
27 2o1s:B 493 144 0.0562 0.0771 0.2639 9.95e-05 2o1s:D
28 2o1s:A 536 144 0.0562 0.0709 0.2639 1.00e-04 2o1s:C
29 6ouv:A 595 188 0.0710 0.0807 0.2553 3.25e-04 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
30 6ouv:A 595 137 0.0562 0.0639 0.2774 0.002 2o1x:A, 2o1x:B, 6ouv:B, 8v9i:A, 8v9i:B
31 8a9c:B 520 152 0.0577 0.0750 0.2566 3.72e-04
32 6xxg:AAA 560 188 0.0710 0.0857 0.2553 4.00e-04 6ouw:A
33 6xxg:AAA 560 137 0.0562 0.0679 0.2774 0.003 6ouw:A
34 6xxg:BBB 539 188 0.0710 0.0891 0.2553 4.33e-04 2o1x:C, 2o1x:D
35 6xxg:BBB 539 172 0.0651 0.0816 0.2558 0.007 2o1x:C, 2o1x:D
36 8bzx:B 568 99 0.0399 0.0475 0.2727 7.67e-04
37 8bzx:A 546 99 0.0399 0.0495 0.2727 8.97e-04
38 2g28:B 801 90 0.0429 0.0362 0.3222 0.004 2g28:A, 2iea:A, 2iea:B, 1l8a:B, 1l8a:A, 3lpl:A, 3lpl:B, 3lq2:A, 3lq2:B, 3lq4:A, 3lq4:B, 2qta:A, 2qta:B, 2qtc:A, 2qtc:B, 1rp7:A, 1rp7:B
39 2g28:B 801 214 0.0769 0.0649 0.2430 0.078 2g28:A, 2iea:A, 2iea:B, 1l8a:B, 1l8a:A, 3lpl:A, 3lpl:B, 3lq2:A, 3lq2:B, 3lq4:A, 3lq4:B, 2qta:A, 2qta:B, 2qtc:A, 2qtc:B, 1rp7:A, 1rp7:B
40 2g25:B 831 90 0.0429 0.0349 0.3222 0.004 2g25:A
41 2g25:B 831 214 0.0769 0.0626 0.2430 0.084 2g25:A
42 8r2h:B 701 189 0.0725 0.0699 0.2593 0.077 8r2h:A
43 7a9g:AAA 549 191 0.0577 0.0710 0.2042 0.12 7a9g:BBB, 7a9h:AAA, 7a9h:BBB, 8ogh:A, 8ogh:B
44 5uxt:A 33 18 0.0148 0.3030 0.5556 3.0 5uxt:C
45 5w81:A 1173 64 0.0281 0.0162 0.2969 3.6
46 7vcp:A 490 45 0.0237 0.0327 0.3556 4.0
47 8c8j:A 698 75 0.0311 0.0301 0.2800 5.8
48 5fcz:A 499 47 0.0251 0.0341 0.3617 6.1 4c7f:A, 4c7f:B, 4c7g:A, 1hp5:A, 1jak:A, 1m01:A, 1m03:A, 1m04:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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