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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MNFKKYEENLVASIEEVIQRIIDDKHRPNIIGKTRVGAEVSDYLEDEFVKYISSGKSSSLYDAQGAPKEKTKNPWDARCK
FKFMDREEEIWIDFKAFKITNMDSNPDIGTPNKIVKFIHEGNFYLVFVLVYYESKQDGVEFVKYNNDYKKVYLLKDVNES
FRINPKPQMQVNIAAEPTYRTREEFIHFFVKKWKESFERQIKSLEKKEIMLKDLEDKLKNSNDNSI

The query sequence (length=226) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5tgq:A 226 226 1.0000 1.0000 1.0000 2.63e-167 5tgx:A, 5tgx:B, 5tgx:C, 5tgx:D, 5th3:A, 5th3:B, 5th3:C, 5th3:D
2 6ke6:SH 112 47 0.0841 0.1696 0.4043 1.9
3 6yxs:A 359 64 0.0885 0.0557 0.3125 2.2 3fi8:A, 6yxt:A
4 7d4i:SH 182 47 0.0841 0.1044 0.4043 2.9 7d5t:SH, 6lqs:SH, 6lqt:SH
5 5wyj:SH 174 47 0.0841 0.1092 0.4043 3.3 7d63:SH, 6lqp:SH, 6lqq:SH, 6lqr:SH, 6lqu:SH, 6lqv:SH, 7suk:L6
6 6org:A 450 52 0.0664 0.0333 0.2885 3.9 6or4:A, 6or4:B, 6orf:A, 6orf:B, 6org:B, 6orh:A, 6orh:B
7 8cbj:G 232 47 0.0841 0.0819 0.4043 4.0 7a1g:T, 7ajt:DG, 7aju:DG, 7b7d:T, 8bn3:S6, 8bqd:T, 8bqx:T, 8c00:T, 8c01:T, 8c83:T, 8cah:T, 8cas:T, 8ccs:j, 8cdl:j, 8cdr:j, 8ceh:j, 8cf5:j, 8cg8:j, 8cgn:j, 8civ:j, 8cku:j, 8cmj:j, 5dat:S6, 5dat:s6, 5dc3:S6, 5dc3:s6, 5dge:S6, 5dge:s6, 5dgf:S6, 5dgf:s6, 5dgv:S6, 5dgv:s6, 6eml:T, 8eub:BG, 8evp:BG, 8evq:BG, 8evr:BG, 8evs:BG, 8evt:BG, 8ewb:BG, 8ewc:BG, 6fai:G, 5fci:S6, 5fci:s6, 5fcj:S6, 5fcj:s6, 6gq1:w, 6gqb:w, 6gqv:w, 6hhq:H, 6hhq:s6, 5i4l:S6, 5i4l:s6, 6i7o:T, 6i7o:Tb, 3j16:C, 3j6x:S6, 3j6y:S6, 3j77:S6, 3j78:S6, 5juo:DB, 5jup:DB, 5jus:DB, 5jut:DB, 5juu:DB, 8k2d:SG, 8k82:SG, 5ll6:T, 5lyb:S6, 5lyb:s6, 5m1j:G2, 5mc6:T, 5mei:s6, 5mei:H, 7mpi:BG, 7mpj:BG, 7n8b:BG, 5ndg:S6, 5ndg:s6, 5ndv:s6, 5ndw:S6, 5ndw:s6, 7nrc:ST, 7nrd:ST, 5obm:S6, 5obm:s6, 5on6:s6, 5on6:H, 7osa:eS6, 7osm:eS6, 6q8y:T, 6rbd:G, 6rbe:G, 7rr5:SG, 6s47:BH, 6snt:G, 6sv4:T, 6sv4:Tb, 6sv4:Tc, 6t4q:SG, 6t7i:SG, 6t7t:SG, 6t83:Gb, 6t83:h, 5tbw:H, 5tbw:s6, 6tb3:T, 5tga:S6, 5tga:s6, 5tgm:S6, 5tgm:s6, 6tnu:T, 5tzs:3, 4u3m:S6, 4u3m:s6, 4u3n:S6, 4u3n:s6, 4u3u:S6, 4u3u:s6, 4u4n:S6, 4u4n:s6, 4u4o:S6, 4u4o:s6, 4u4q:S6, 4u4q:s6, 4u4r:S6, 4u4r:s6, 4u4u:S6, 4u4u:s6, 4u4y:S6, 4u4y:s6, 4u4z:S6, 4u4z:s6, 4u50:S6, 4u50:s6, 4u51:S6, 4u51:s6, 4u52:S6, 4u52:s6, 4u53:S6, 4u53:s6, 4u55:S6, 4u55:s6, 4u56:S6, 4u56:s6, 4u6f:S6, 4u6f:s6, 4uer:Y, 4v88:AG, 4v88:CG, 4v8y:AG, 4v8z:AG, 4v92:BG, 6wdr:G, 5wlc:L6, 6woo:GG, 7wtl:SG, 7wtm:SG, 7wtn:SG, 7wto:SG, 7wtp:SG, 7wtq:SG, 7wtr:SG, 6xiq:w, 6xir:w, 8y0u:SG, 6y7c:G, 6z6j:SG, 6z6k:SG, 6zce:H, 7zpq:AG, 6zqb:DG, 6zqc:DG, 6zqd:DG, 6zqe:DG, 6zqf:DG, 6zqg:DG, 7zrs:AG, 6zu9:T, 7zuw:AG, 7zux:DG, 6zvi:o, 7zw0:sT
8 3jwh:A 191 20 0.0310 0.0366 0.3500 4.3 3jwh:B
9 8c3a:CT 236 59 0.0973 0.0932 0.3729 4.3 8c3a:I, 8cq7:I, 8cq7:CT, 8cqw:I, 8cqw:CT, 8cre:I, 8cre:CT, 8oeq:I, 8oeq:CT, 7pzy:H, 7q08:H, 7q0f:H, 7q0p:H, 7q0r:H, 8q5i:H
10 5ndv:S6 200 47 0.0841 0.0950 0.4043 4.3
11 4toi:A 307 82 0.1150 0.0847 0.3171 4.7 4a2i:B, 8a3l:B, 7abz:g, 7ac7:g, 7acj:g, 7acr:g, 4adv:B, 5afi:b, 7af3:B, 7af5:B, 7af8:B, 7afa:B, 7afd:B, 7afh:B, 7afk:B, 7afn:B, 8akn:C, 8am9:C, 6awb:E, 6awc:E, 6awd:E, 9ax7:B, 9ax8:b, 8aye:B, 8b0x:B, 7b5k:b, 8b7y:D, 8bf7:f, 8bge:f, 8bgh:f, 8bh4:f, 8bhj:f, 8bhl:f, 8bhn:f, 8bhp:f, 8bil:f, 8bim:f, 7boe:B, 7boh:B, 6bu8:B, 6by1:AB, 6by1:BB, 6c4i:b, 8cai:B, 8caz:B, 8cf8:B, 9cg5:B, 9cg6:B, 9cg7:B, 7cpj:b, 7d6z:i, 7d80:C, 6dnc:OA, 8eiu:B, 8ekc:b, 8emm:B, 6enf:b, 6enj:b, 6enu:b, 8eyt:B, 9fbv:B, 8fiz:AJ, 8fto:B, 8fzd:b, 8fze:b, 8fzf:b, 8fzg:b, 8fzh:b, 8fzi:b, 8fzj:b, 8g2u:a, 8g31:w, 8g34:w, 8g38:w, 8g6w:B, 8g7p:b, 8g7q:b, 8g7r:b, 8g7s:b, 6gwt:b, 6gxm:b, 6gxn:b, 6gxo:b, 6gxp:b, 6h4n:b, 5h5u:i, 6h58:b, 6h58:bb, 6hrm:g, 8hsp:B, 8htz:B, 8hu1:B, 6i7v:AB, 6i7v:BB, 8ifb:B, 8ifc:B, 5iqr:g, 5it8:AB, 5it8:BB, 5j5b:AB, 5j5b:BB, 5j7l:AB, 5j7l:BB, 5j88:AB, 5j88:BB, 5j8a:AB, 5j8a:BB, 3j9y:b, 3j9z:SB, 5j91:AB, 5j91:BB, 3ja1:SB, 3jbu:B, 3jbv:B, 3jcd:b, 3jce:b, 3jcj:j, 3jcn:d, 5jc9:AB, 5jc9:BB, 7jss:G, 7jsw:G, 7jsz:G, 8jsg:j, 5jte:AB, 7jt1:G, 7jt2:G, 7jt3:G, 5ju8:AB, 7k00:B, 8k3o:B, 8k4e:B, 7k50:G, 7k51:G, 7k52:G, 7k53:G, 7k54:G, 7k55:G, 5kcr:1b, 5kcs:1b, 5kps:7, 5kpv:6, 5kpw:6, 5kpx:6, 5l3p:b, 6lkq:A, 7lv0:G, 5lza:b, 5lzb:b, 5lzc:b, 5lzd:b, 5lze:b, 5lzf:b, 7m5d:g, 5mdv:g, 5mdw:g, 5mdy:g, 5mdz:g, 5me0:B, 5me1:B, 5mgp:b, 5my1:B, 7n1p:SB, 7n2c:SB, 7n2u:SB, 7n2v:SB, 7n30:SB, 7n31:SB, 7nar:B, 7nat:B, 7nau:B, 7nav:B, 7nax:B, 7nbu:B, 5no3:B, 5np6:E, 6nqb:B, 7nso:b, 7nsp:b, 7nsq:b, 5nwy:1, 7nwt:g, 7nww:f, 7o19:AB, 7o1a:AB, 7o1c:AB, 5o2r:b, 7o5h:B, 6o7k:j, 6o9j:7, 6o9k:b, 7oe0:B, 7oe1:B, 6ofx:G, 6og7:G, 6ogf:G, 6ogg:G, 6ogi:G, 7oif:f, 7oig:f, 7oii:f, 7oiz:B, 7oj0:B, 6om6:g, 6ore:g, 6orl:g, 6osk:g, 6osq:g, 6ost:g, 6ot3:g, 7ot5:f, 7otc:b, 6ouo:g, 8p16:g, 8p17:g, 8p18:g, 7p3k:B, 8peg:B, 8phj:B, 7pjs:b, 7pjt:b, 7pju:b, 7pjv:b, 7pjw:b, 7pjx:b, 7pjy:b, 7pjz:b, 8pkl:B, 8pva:B, 7q4k:AB, 8q4f:B, 6q97:g, 6q98:g, 6q9a:g, 8qbt:j, 7qg8:1, 7qgh:1, 7qgn:1, 7qgr:1, 8qk7:g, 8qoa:B, 8r3v:B, 8r3v:B2, 8r6c:B, 8r8m:B, 8rcl:B, 8rcl:B2, 8rcm:B, 8rcm:B2, 8rcs:B, 8rcs:B2, 8rct:B, 8rct:B2, 7s1g:D, 7s1h:D, 7s1i:D, 7s1j:D, 7s1k:D, 7sa4:g, 7ss9:G, 7ssd:G, 7ssl:G, 7ssn:G, 7sso:G, 7ssw:G, 7st2:G, 7st6:G, 7st7:G, 8syl:b, 6szs:b, 8t5d:a, 6tbv:S021, 6tc3:S021, 7tos:S02, 4u1u:AB, 4u1u:CB, 4u1v:AB, 4u1v:CB, 4u20:AB, 4u20:CB, 4u24:AB, 4u24:CB, 4u25:AB, 4u25:CB, 4u26:AB, 4u26:CB, 4u27:AB, 4u27:CB, 5u4i:b, 5u9f:B, 5u9g:B, 7ug7:SB, 7uph:W, 8upo:G, 8upr:G, 8uql:G, 8uqm:G, 8uqp:G, 8ur0:G, 8urh:G, 8uri:G, 8urx:G, 8ury:G, 5uyk:B, 5uyl:B, 5uym:B, 5uyn:B, 5uyp:B, 5uyq:B, 5uz4:B, 4v4h:AB, 4v4h:CB, 4v4q:AB, 4v4q:CB, 4v4v:AB, 4v50:AB, 4v50:CB, 4v52:AB, 4v52:CB, 4v53:AB, 4v53:CB, 4v54:AB, 4v54:CB, 4v55:AB, 4v55:CB, 4v56:AB, 4v56:CB, 4v57:AB, 4v57:CB, 4v5b:BB, 4v5b:DB, 4v5h:AB, 4v5y:AB, 4v5y:CB, 4v64:AB, 4v64:CB, 4v65:AB, 4v66:AB, 4v69:AB, 4v6c:AB, 4v6c:CB, 4v6d:AB, 4v6d:CB, 4v6e:AB, 4v6e:CB, 4v6k:BF, 4v6l:AF, 4v6m:AB, 4v6n:BE, 4v6o:AE, 4v6p:AE, 4v6q:AE, 4v6r:AE, 4v6s:BD, 4v6t:AB, 4v6v:AB, 4v6y:AB, 4v6z:AB, 4v70:AB, 4v71:AB, 4v72:AB, 4v73:AB, 4v74:AB, 4v75:AB, 4v76:AB, 4v77:AB, 4v78:AB, 4v79:AB, 4v7a:AB, 4v7b:AB, 4v7c:AB, 4v7d:BB, 4v7i:BB, 4v7s:AB, 4v7s:CB, 4v7t:AB, 4v7t:CB, 4v7u:AB, 4v7u:CB, 4v7v:AB, 4v7v:CB, 4v85:AB, 4v89:AB, 4v9c:AB, 4v9c:CB, 4v9d:AB, 4v9d:BB, 4v9o:BB, 4v9o:DB, 4v9o:FB, 4v9o:HB, 4v9p:BB, 4v9p:DB, 4v9p:FB, 4v9p:HB, 8vs9:S02, 8vsa:S02, 6vu3:G, 6vwl:a, 6vwm:a, 6vwn:a, 6vyq:G, 6vyr:G, 6vys:G, 6vyt:G, 6vyu:G, 6vyw:G, 6vyx:G, 6vyy:G, 6vyz:G, 6vz2:G, 6vz3:G, 6vz5:G, 6vz7:G, 6vzj:G, 6w7m:B, 5wdt:b, 6wd0:G, 6wd1:G, 6wd2:G, 6wd3:G, 6wd4:G, 6wd5:G, 6wd6:G, 6wd7:G, 6wd8:G, 6wd9:G, 6wda:G, 6wdb:G, 6wdc:G, 6wdd:G, 6wde:G, 6wdf:G, 6wdg:G, 6wdh:G, 6wdi:G, 6wdj:G, 6wdk:G, 6wdl:G, 6wdm:G, 5we4:b, 5we6:b, 4wf1:AB, 4wf1:CB, 5wf0:b, 5wfk:b, 5wfs:b, 6wnv:G, 6wnw:G, 4woi:AB, 4woi:DB, 4www:QB, 4www:XB, 6x6t:G, 6x7f:G, 6x7k:G, 6x9q:G, 6xdq:G, 6xdr:G, 6xe0:A, 6xgf:G, 6xii:G, 6xij:G, 6xza:B1, 6xzb:B1, 6y69:b, 7y7c:B, 7y7d:B, 7y7e:B, 7y7f:B, 7y7g:B, 7y7h:B, 4ybb:AB, 4ybb:BB, 2ykr:B, 6ysr:b, 6yss:b, 6yst:b, 6ysu:b, 6ztj:AB, 6ztl:AB, 6ztm:AB, 6ztn:AB, 6zto:AB, 6ztp:AB, 7zta:S021, 6zu1:AB
12 8a22:BF 370 54 0.0664 0.0405 0.2778 5.8 8apn:BF, 8apo:BF
13 5tsh:E 387 63 0.0841 0.0491 0.3016 5.9 5tsg:B, 5tsg:C, 5tsg:D, 5tsh:A, 5tsh:B, 5tsh:C, 5tsh:D, 5tsh:F, 5zfr:A, 5zfr:B, 5zfr:C
14 6fyx:G 230 47 0.0796 0.0783 0.3830 9.4 6fyy:G, 6gsm:G, 6gsn:G, 8i7j:G, 5it7:G, 5it9:G, 3j80:G, 3j81:G, 3jam:G, 3jap:G, 8rw1:G, 8s8d:G, 8s8e:G, 8s8f:G, 8s8g:G, 8s8h:G, 8s8i:G, 8s8j:G, 6uz7:G

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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