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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MMDLAYVCEWEKWSKSTHCPSVPLACAWSCRNLIAFTMDLRSDDQDLTRMIHILDTEHPWDLHSIPSEHHEAITCLEWDQ
SGSRLLSADADGQIKCWSMADHLANSWESSVGSLVEGDPIVALSWLHNGVKLALHVEKSGASSFGEKFSRVKFSPSLTLF
GGKPMEGWIAVTVSGLVTVSLLKPSGQVLTSTESLCRLRGRVALADIAFTGGGNIVVATADGSSASPVQFYKVCVSVVSE
KCRIDTEILPSLFMRCTTDLNRKDKFPAITHLKFLARDMSEQVLLCASSQTSSIVECWSLRKETILKWRILSATNDLDRV
SAVALPKLPISLTNTDLKVASDTQFYPGLGLALAFHDGSVHIVHRLSLQTMAVFYSSVHLKAMQLSWTSLALVGIDSHGK
LSVLRLSPSMGHPLEVGLALRHLLFLLEYCMVTGYDWWDILLHVQPSMVQSLVEKLHEEYTRQTAALQQVLSTRILAMKA
SLCKLSPCTVTRVCDYHTKLFLIAISSTLKSLLRPHFLNTPDKSPGDRLTEICTKITDVDIDKVMINLKTEEFVLDMNTL
QALQQLLQWVGDFVLYLLASLPNLRPGHSFLRDGTSLGMLRELMVVIRIWGLLKPSCLPVYTATSDTQDSMSLLFRLLTK
LWICCRDEGPASEPDEALVDECCLLPSQLLIPSLDWLPASDGLVSRLQPKQPLRLQFGRAPPKIDHLRRLHLGACPTEEC
KACTRCGCVTMLKSPNRTTAVKQWEQRWIKNCLCGGLWWRVPLSYP

The query sequence (length=766) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 7emf:P 766 766 1.0000 1.0000 1.0000 0.0 8gxq:p, 8gxs:p
2 8shj:C 306 59 0.0274 0.0686 0.3559 0.052 8t55:C
3 8shj:C 306 78 0.0274 0.0686 0.2692 1.6 8t55:C
4 8shj:A 334 59 0.0274 0.0629 0.3559 0.064 8shj:B, 8t55:A, 8t55:B
5 8shj:A 334 74 0.0274 0.0629 0.2838 1.5 8shj:B, 8t55:A, 8t55:B
6 7mq8:LJ 469 35 0.0183 0.0299 0.4000 0.35 7mq9:LJ, 7mqa:LJ
7 5xxb:V 63 55 0.0235 0.2857 0.3273 0.74
8 7aju:UL 779 50 0.0222 0.0218 0.3400 0.83 5wyj:BB, 5wyk:BB, 6zqd:UL, 6zqe:UL, 6zqf:UL
9 7d5s:B2 851 50 0.0222 0.0200 0.3400 0.85 7ajt:UL, 7d4i:B2, 7d5t:B2, 7d63:B2, 6ke6:B2, 6lqp:B2, 6lqq:B2, 6lqr:B2, 6lqs:B2, 6lqt:B2, 6lqu:B2, 6lqv:B2, 7suk:LQ, 5wlc:LQ, 6zqa:UL, 6zqb:UL, 6zqc:UL
10 5naf:A 352 67 0.0248 0.0540 0.2836 1.2 5naf:B
11 3mmr:A 308 76 0.0287 0.0714 0.2895 1.3 3sl0:A, 3sl1:A
12 6lqs:B1 806 100 0.0339 0.0323 0.2600 1.6 7aju:UA, 7d4i:B1, 7d5t:B1, 7d63:B1, 6lqr:B1, 6lqt:B1, 6lqv:B1, 6zqd:UA, 6zqe:UA, 6zqf:UA
13 6lqs:B1 806 31 0.0144 0.0136 0.3548 2.4 7aju:UA, 7d4i:B1, 7d5t:B1, 7d63:B1, 6lqr:B1, 6lqt:B1, 6lqv:B1, 6zqd:UA, 6zqe:UA, 6zqf:UA
14 7ajt:UA 834 100 0.0339 0.0312 0.2600 2.1 7d5s:B1, 6ke6:B1, 6lqp:B1, 6lqq:B1, 6lqu:B1, 6nd4:O, 7suk:LO, 5wlc:LO, 6zqa:UA, 6zqb:UA, 6zqc:UA
15 7ajt:UA 834 31 0.0144 0.0132 0.3548 2.5 7d5s:B1, 6ke6:B1, 6lqp:B1, 6lqq:B1, 6lqu:B1, 6nd4:O, 7suk:LO, 5wlc:LO, 6zqa:UA, 6zqb:UA, 6zqc:UA
16 6rxt:UA 839 45 0.0183 0.0167 0.3111 2.2 5oql:A, 6rxu:UA, 6rxv:UA, 6rxx:UA, 6rxy:UA, 6rxz:UA
17 6rxt:UA 839 31 0.0144 0.0131 0.3548 5.8 5oql:A, 6rxu:UA, 6rxv:UA, 6rxx:UA, 6rxy:UA, 6rxz:UA
18 7mqa:LQ 830 33 0.0183 0.0169 0.4242 2.6 7mq8:LQ, 7mq9:LQ
19 3ssn:B 350 87 0.0326 0.0714 0.2874 3.4
20 6rm3:SGG 330 34 0.0170 0.0394 0.3824 3.5
21 6rxt:UL 785 31 0.0170 0.0166 0.4194 7.4 6rxu:UL, 6rxv:UL, 6rxx:UL, 6rxy:UL, 6rxz:UL
22 6exn:J 342 30 0.0144 0.0322 0.3667 8.6 5lj3:J, 5lj5:J, 5mps:J, 5mq0:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218