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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLTYGAPFNFPRWIDEHAHLLKPPVGNRQVWQDSDFIVTVVGGPNHRTDYHDDPLEEFFYQLRGNAYLNLWVDGRRERAD
LKEGDIFLLPPHVRHSPQRPEAGSACLVIERQRPAGMLDGFEWYCDACGHLVHRVEVQLKSAVTDLPPLFESFYASEDKR
RCPHCGQVHPGRAA

The query sequence (length=174) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6vi8:A 176 174 0.9943 0.9830 0.9943 6.25e-130 6bvp:A, 6bvq:A, 6bvr:A, 6bvs:A, 6cd3:A, 6d60:A, 6d61:A, 6d62:A, 4hsj:A, 4hsl:A, 4hvo:A, 4hvq:A, 4hvr:A, 4i3p:A, 4l2n:A, 4r52:A, 5v26:A, 5v26:B, 5v27:A, 5v28:A, 6vi5:A, 6vi6:A, 6vi7:A, 6vi9:A, 6via:A, 6vib:A, 4wzc:A, 6x11:A, 1yfu:A, 1yfw:A, 1yfx:A, 1yfy:A
2 5tk5:A 283 148 0.3161 0.1943 0.3716 2.95e-25 5tkq:A
3 3fe5:A 283 154 0.3218 0.1979 0.3636 9.95e-25
4 7eg3:E 194 62 0.0977 0.0876 0.2742 0.14 7eg2:A, 7eg2:B, 7eg2:C, 7eg2:D, 7eg2:E, 7eg2:F, 7eg2:G, 7eg2:H, 7eg2:I, 7eg2:J, 7eg2:K, 7eg2:L, 7eg2:M, 7eg2:N, 7eg2:O, 7eg2:P, 7eg3:A, 7eg3:B, 7eg3:C, 7eg3:D, 7eg3:F, 7eg3:G, 7eg3:H, 7eg3:I, 7eg3:J, 7eg3:K, 7eg3:L, 7eg3:M, 7eg3:N, 7eg3:O, 7eg3:P, 1ej3:A, 1ej3:B, 1sl8:A, 1uhh:A, 1uhh:B, 1uhi:A, 1uhi:B, 1uhj:A, 1uhj:B, 1uhk:A, 1uhk:B, 5zab:A, 5zab:B, 5zab:C, 5zab:D, 5zab:E, 5zab:F, 5zab:G, 5zab:H, 5zab:I, 5zab:J, 5zab:K, 5zab:L, 5zab:M, 5zab:N, 5zab:O, 5zab:P
5 3aq5:A 117 28 0.0632 0.0940 0.3929 0.41 3aq5:B, 3aq6:A, 3aq6:B, 3aq7:A, 3aq7:B, 3aq8:A, 3aq8:B, 3aq9:A, 3aq9:B
6 4qiw:B 1069 70 0.1379 0.0225 0.3429 0.62 4qiw:J
7 6kf3:B 1114 70 0.1379 0.0215 0.3429 0.68 9bct:B, 9bcu:B, 6kf4:B, 6kf9:B
8 4nqg:A 197 62 0.0977 0.0863 0.2742 2.7 4nqg:B
9 7zvm:A 104 53 0.1264 0.2115 0.4151 2.7
10 3fhq:A 601 62 0.0862 0.0250 0.2419 4.3 3fha:A, 3fha:B, 3fha:C, 3fha:D, 3fhq:B, 3fhq:D, 3fhq:F
11 6gnf:A 522 78 0.1092 0.0364 0.2436 5.2 6gnf:C
12 1szb:A 167 45 0.0920 0.0958 0.3556 5.6 1szb:B
13 4tpu:A 169 70 0.1092 0.1124 0.2714 5.6
14 5y7q:A 546 24 0.0690 0.0220 0.5000 5.9 4r89:A, 4r89:E, 4r8a:A, 4r8a:F, 5y7g:A, 5y7g:B, 5y7g:C, 5z6w:A
15 8oki:B 1101 70 0.1322 0.0209 0.3286 7.0 8cro:B, 8orq:B, 8p2i:B, 8rbo:B
16 5e1r:C 358 41 0.0862 0.0419 0.3659 7.6 5e1r:A, 5e1r:B, 5e1r:D, 5e1r:E, 5e1r:F
17 4qma:A 192 57 0.1149 0.1042 0.3509 8.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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