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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVR
ERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGR
TLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIA
PLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF

The query sequence (length=284) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5lht:A 284 284 1.0000 1.0000 1.0000 0.0 5lhu:A, 1nh8:A, 5u99:A
2 2vd3:A 289 284 0.3239 0.3183 0.3239 7.56e-33 2vd3:B
3 1h3d:A 288 284 0.3134 0.3090 0.3134 7.58e-32 1q1k:A
4 4yb6:A 296 288 0.3028 0.2905 0.2986 7.39e-30 5ub9:A, 5ub9:B, 5ubg:A, 5ubg:B, 5ubh:A, 5ubh:B, 5ubi:A, 5ubi:B, 4yb5:A, 4yb5:E, 4yb5:B, 4yb5:C, 4yb5:F, 4yb5:D, 4yb6:E, 4yb6:B, 4yb6:C, 4yb6:F, 4yb6:D, 4yb7:B, 4yb7:C, 4yb7:D, 4yb7:E, 4yb7:I, 4yb7:K, 4yb7:A, 4yb7:F, 4yb7:G, 4yb7:H, 4yb7:J, 4yb7:L
5 7dah:C 288 289 0.3028 0.2986 0.2976 2.19e-27 7dah:F
6 6czm:E 342 317 0.2993 0.2485 0.2681 1.58e-19 6czm:A, 6czm:C, 6czm:D
7 1usy:G 203 172 0.1725 0.2414 0.2849 8.12e-17 1usy:F, 1usy:E, 1usy:H
8 6fca:A 209 179 0.2077 0.2823 0.3296 4.00e-16 6fct:A, 6fcw:A, 6fcy:A, 6fd9:A, 6ftt:E, 6ftt:H, 6ftt:G, 6ftt:F, 6fu2:C, 6fu2:D, 6fu7:C, 6fu7:D, 6fua:C, 6fua:D, 6r02:E, 6r02:F, 6r02:G, 6r02:H, 7z6r:C, 7z6r:D, 7z8u:A
9 1z7n:F 205 174 0.1761 0.2439 0.2874 2.58e-14 1z7m:G, 1z7m:E, 1z7m:H, 1z7n:E, 1z7n:G, 1z7n:H
10 6czm:F 315 309 0.2782 0.2508 0.2557 5.85e-13 6czm:B
11 6az3:f 130 82 0.0810 0.1769 0.2805 0.38 8a3w:f, 8a98:f, 3jcs:f, 8ovj:f, 8rxh:Lf, 8rxx:Lf
12 5ixj:D 394 128 0.1162 0.0838 0.2578 2.2 6am8:A, 6am8:B, 6am8:C, 6am8:D, 6am9:A, 6am9:B, 6am9:C, 6am9:D, 6amh:A, 6amh:B, 6amh:C, 6amh:D, 6ami:A, 6ami:B, 6ami:C, 6ami:D, 6cut:A, 6cut:B, 6cut:C, 6cut:D, 6cuz:A, 6cuz:D, 5dw0:A, 5dw0:B, 5dw0:C, 5dw0:D, 5dw3:A, 5dw3:B, 5dw3:C, 5dw3:D, 5ixj:A, 5ixj:B, 5ixj:C, 7rnp:A, 7rnp:B, 7rof:A, 7rof:D, 5t6m:A, 5t6m:B, 5t6m:C, 5t6m:D, 1v8z:A, 1v8z:B, 1v8z:C, 1v8z:D, 5vm5:A, 5vm5:B, 5vm5:C, 5vm5:D, 1wdw:B, 1wdw:D, 1wdw:F, 1wdw:H, 1wdw:J, 1wdw:L
13 4ywr:A 228 50 0.0599 0.0746 0.3400 4.6
14 2ggq:A 401 68 0.0739 0.0524 0.3088 4.7 5z09:A, 5z09:B, 5z09:C, 5z09:D
15 3czk:A 618 26 0.0493 0.0227 0.5385 7.0 3czg:A, 3czl:A
16 7p73:A 420 117 0.1232 0.0833 0.2991 7.4 8ael:A, 7p74:A, 7pc9:A, 7pc9:B, 7r2m:A, 7r2m:D, 7r2t:A
17 3vfq:A 375 73 0.0915 0.0693 0.3562 9.4 4d86:A, 5o2d:A, 3q6z:A, 3q71:A
18 3gju:A 458 42 0.0493 0.0306 0.3333 9.6
19 7ern:C 284 70 0.0599 0.0599 0.2429 9.8 7erm:A, 7erm:B, 7erm:C, 7erm:D, 7ern:A, 7ern:B, 7ern:D, 7ero:A, 7ero:B, 7ero:C, 7ero:D
20 2g46:A 119 35 0.0528 0.1261 0.4286 9.9 2g46:B, 3kmt:A, 3kmt:B, 3kmt:C

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218