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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLPKLVITHRVHEEILQLLAPHCELITNQTDSTLTREEILRRCRDAQAMMAFMPDRVDADFLQACPELRVIGCALKGFDN
FDVDACTARGVWLTFVPDLLTVPTAELAIGLAVGLGRHLRAADAFVRSGKFRGWQPRFYGTGLDNATVGFLGMGAIGLAM
ADRLQGWGATLQYHEAKALDTQTEQRLGLRQVACSELFASSDFILLALPLNADTLHLVNAELLALVRPGALLVNPCRGSV
VDEAAVLAALERGQLGGYAADVFEMEDWARADRPQQIDPALLAHPNTLFTPHIGSAVRAVRLEIERCAAQNILQALAGER
PINAVNRLP

The query sequence (length=329) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4e5p:A 332 329 0.9909 0.9819 0.9909 0.0 4e5k:A, 4e5k:B, 4e5k:C, 4e5k:D, 4e5m:A, 4e5m:B, 4e5n:A, 4e5n:B, 4e5n:C, 4e5n:D, 4e5n:E, 4e5n:F, 4e5n:G, 4e5n:H, 4e5p:B, 4e5p:C, 4e5p:D, 4e5p:E, 4e5p:F, 4ebf:A, 4ebf:B, 4ebf:C, 4ebf:D, 4nu5:A, 4nu5:B, 4nu6:A, 4nu6:B
2 6ih6:A 330 328 0.5593 0.5576 0.5610 6.28e-127 6ih3:A, 6ih5:B, 6ih6:B
3 5aov:A 334 332 0.3435 0.3383 0.3404 8.63e-66
4 6bii:A 332 330 0.3587 0.3554 0.3576 8.87e-63 6bii:B
5 2dbq:A 333 332 0.3343 0.3303 0.3313 2.59e-52 2dbr:A, 2dbr:B, 2dbr:C, 2dbr:D, 2dbr:E, 2dbr:F, 2dbz:A, 2dbz:B
6 7dkm:A 306 283 0.2766 0.2974 0.3216 2.33e-41 7cvp:B, 6cwa:A, 6cwa:B, 7dkm:B, 7ewh:A, 7ewh:B, 2g76:A, 2g76:B, 5n53:B, 5n53:A, 5n6c:A, 5n6c:B, 5nzo:B, 5nzo:A, 5nzp:B, 5nzp:A, 5nzq:B, 5nzq:A, 5ofm:B, 5ofm:A, 5ofv:B, 5ofv:A, 5ofw:B, 5ofw:A, 6plf:A, 6plf:B, 6plg:A, 6plg:B, 6plg:C, 6plg:D, 6plg:E, 6plg:F, 6plg:G, 6plg:H, 6rih:A, 6rih:B, 6rj2:A, 6rj2:B, 6rj3:A, 6rj3:B, 6rj5:A, 6rj5:B, 6rj6:A, 6rj6:B, 7va1:B, 7va1:A, 7va1:C, 7va1:D
7 2gcg:A 324 322 0.3040 0.3086 0.3106 2.05e-38 2gcg:B, 2gcg:C, 2gcg:D
8 3baz:A 311 262 0.2401 0.2540 0.3015 4.70e-35
9 3dc2:A 526 291 0.2918 0.1825 0.3299 1.89e-34 3dc2:B, 3ddn:B
10 5v6q:B 319 316 0.2948 0.3041 0.3070 3.83e-33 5j23:A, 5j23:B, 5j23:C, 5j23:D, 5v6q:A, 5v6q:C, 5v6q:D, 5v7g:A, 5v7g:B, 5v7g:C, 5v7g:D, 5v7n:A, 5v7n:B, 5v7n:C, 5v7n:D
11 4zgs:A 346 275 0.2705 0.2572 0.3236 2.71e-31 4zgs:B, 4zgs:C, 4zgs:D, 4zgs:E, 4zgs:F, 4zgs:G, 4zgs:H
12 5z20:F 336 277 0.2857 0.2798 0.3394 2.06e-29 5z20:A, 5z20:B, 5z20:C, 5z20:D, 5z20:E
13 1wwk:A 304 317 0.2705 0.2928 0.2808 1.60e-28 1wwk:B
14 7cvp:A 254 226 0.2219 0.2874 0.3230 3.13e-28
15 3kb6:B 334 265 0.2249 0.2216 0.2792 4.29e-28 3kb6:A, 3kb6:C, 3kb6:D
16 2ekl:A 312 284 0.2097 0.2212 0.2430 4.97e-28
17 2dld:A 337 313 0.2614 0.2552 0.2748 2.12e-25 2dld:B
18 4cuk:A 330 304 0.2705 0.2697 0.2928 3.71e-24 4cuk:D
19 1j49:A 332 313 0.2584 0.2560 0.2716 4.02e-24 1j49:B
20 8ati:A 330 306 0.2736 0.2727 0.2941 1.08e-23 8ati:B, 8ati:C, 8ati:D, 4lcj:A, 4lcj:B, 4lcj:C, 4lcj:D, 4lcj:E, 4lcj:F, 4lcj:G, 4lcj:H, 2ome:A, 2ome:B, 2ome:C, 2ome:D, 2ome:E, 2ome:F, 2ome:G, 2ome:H, 6wkw:D, 6wkw:C, 6wkw:B, 6wkw:A
21 3wr5:A 401 309 0.2614 0.2145 0.2783 2.33e-23 6juj:A, 6juj:B, 6juk:A, 6juk:B, 2nad:A, 2nad:B, 8oq2:A, 8oq2:B, 8oq2:C, 8oq2:D, 8oq2:E, 8oq2:F, 3wr5:B, 3wr5:C
22 6cdf:A 333 275 0.2523 0.2492 0.3018 5.64e-23 8ari:A, 8ari:G, 8ari:D, 8ari:F, 8ari:E, 8ari:J, 8ari:H, 8ari:K, 8ari:I, 8ari:P, 8ari:L, 8ari:M, 8ari:N, 8ari:T, 8ari:O, 8ari:Q, 8ari:R, 8ari:U, 8ari:S, 8ari:X, 8ari:B, 8ari:C, 8ari:V, 8ari:W, 6cdr:A, 1hku:A, 1hl3:A, 2hu2:A, 7kwm:A, 4lce:A, 1mx3:A, 4u6q:A, 4u6s:A, 6v89:A, 6v8a:A
23 2w2l:A 346 273 0.2371 0.2254 0.2857 8.83e-23 2w2l:B, 2w2l:C, 2w2l:D
24 2gsd:A 399 309 0.2553 0.2105 0.2718 1.83e-22
25 2p9e:A 406 326 0.2736 0.2217 0.2761 3.30e-22 2p9c:A, 2p9c:B, 2p9e:B, 2p9e:C, 2p9e:D, 2p9g:A, 2p9g:B, 2pa3:A, 1psd:A, 1psd:B, 1sc6:A, 1sc6:B, 1yba:A, 1yba:B, 1yba:C, 1yba:D
26 6t9w:B 383 290 0.2462 0.2115 0.2793 4.75e-22 8bxx:AA, 8bxx:BB, 8bxx:CC, 8bxx:DD, 6t9w:A, 6t9w:C, 6t9x:B, 6t9x:A, 6t9x:C, 6t9x:D, 6tb6:B
27 7arz:A 361 276 0.2310 0.2105 0.2754 9.71e-22
28 1dxy:A 330 223 0.1976 0.1970 0.2915 1.00e-20
29 3jtm:A 351 266 0.2188 0.2051 0.2707 4.37e-20 3n7u:A, 3n7u:B, 3n7u:C, 3n7u:D, 3n7u:E, 3n7u:F, 3n7u:G, 3n7u:H, 3n7u:I, 3n7u:J, 3n7u:K, 3n7u:L
30 8grv:A 336 265 0.1976 0.1935 0.2453 1.25e-19
31 6ttb:A 331 245 0.2067 0.2054 0.2776 1.39e-19
32 4xkj:A 332 272 0.2644 0.2620 0.3199 2.46e-19 4xkj:B
33 5z21:B 331 301 0.2371 0.2356 0.2591 5.36e-19 5z21:A, 5z21:C, 5z21:D
34 7ya3:B 384 209 0.1733 0.1484 0.2727 1.05e-17 7ya3:A, 7ya4:A, 7ya4:B
35 6d4b:A 361 246 0.2128 0.1939 0.2846 1.79e-17 6d4b:B, 6d4c:A, 6d4c:B, 5dn9:A, 5dn9:B
36 1sc6:D 384 303 0.2492 0.2135 0.2706 3.49e-17 1sc6:C
37 6p2i:A 307 271 0.2036 0.2182 0.2472 2.30e-16 6p2i:B
38 4xyb:A 384 277 0.2401 0.2057 0.2852 5.18e-16 4xyb:B, 4xye:A, 4xye:B
39 4prl:A 330 269 0.2280 0.2273 0.2788 1.79e-15 4prl:B
40 4njm:A 303 227 0.1611 0.1749 0.2335 2.73e-15 4njm:B, 4njo:A
41 3kbo:A 312 182 0.1702 0.1795 0.3077 4.24e-15 3kbo:B, 3kbo:C, 3kbo:D
42 5vg6:B 315 221 0.2219 0.2317 0.3303 9.50e-15 5vg6:A, 5vg6:C, 5vg6:D, 5vg6:E, 5vg6:F, 5vg6:G, 5vg6:H, 5vg6:I, 5vg6:J
43 5mh5:A 308 259 0.2097 0.2240 0.2664 2.66e-14 5mh5:B, 5mh6:A, 5mh6:B, 5mh6:C, 5mh6:D, 5mha:A, 5mha:B
44 2yq5:C 331 276 0.2036 0.2024 0.2428 4.13e-14 2yq5:A, 2yq5:B, 2yq5:D
45 6t8y:BBB 375 251 0.2188 0.1920 0.2869 6.20e-14 6t8y:AAA, 6t8y:CCC, 6t8y:DDD, 6t8z:AAA, 6t8z:BBB, 6t8z:CCC, 6t8z:DDD, 6t92:AAA, 6t92:BBB, 6t92:CCC, 6t92:DDD, 6t94:AAA, 6t94:BBB, 6t94:CCC, 6t94:DDD
46 5dt9:A 379 266 0.2188 0.1900 0.2707 3.34e-13
47 7jqh:A 313 194 0.1702 0.1789 0.2887 8.11e-13 7jqi:A, 7jqj:A, 6ovl:A, 6oxn:A, 6p35:A
48 4weq:A 316 266 0.2280 0.2373 0.2820 1.40e-12 4z0p:A
49 3oet:H 378 226 0.1915 0.1667 0.2788 1.04e-11 3oet:A, 3oet:B, 3oet:C, 3oet:D, 3oet:E, 3oet:F, 3oet:G
50 5bqf:A 317 278 0.2249 0.2334 0.2662 1.07e-10 5tsd:A, 5tsd:B, 4xcv:A
51 8j3p:A 374 281 0.1884 0.1658 0.2206 3.46e-10 8j3o:A, 8j3o:B, 8j3o:C, 8j3o:D, 8j3p:B, 8j3p:C
52 4zqb:B 316 186 0.1550 0.1614 0.2742 1.81e-09 4zqb:A
53 2o4c:A 380 106 0.1337 0.1158 0.4151 1.34e-08 2o4c:B
54 1qp8:A 301 187 0.1520 0.1661 0.2674 4.55e-07 1qp8:B
55 5je8:B 294 63 0.0547 0.0612 0.2857 0.52 5je8:A, 5je8:C, 5je8:D
56 7wr3:A 794 93 0.0608 0.0252 0.2151 0.68 7wr3:B, 7wr5:A
57 2vhw:E 373 102 0.0881 0.0777 0.2843 1.3 4lmp:A, 6o7f:A, 2vhv:A, 2vhv:B, 2vhw:A, 2vhw:B, 2vhw:C, 2vhw:D, 2vhw:F, 2vhx:A, 2vhx:B, 2vhx:C, 2vhx:D, 2vhx:E, 2vhx:F, 2vhz:A, 2vhz:B, 2voj:A, 2voj:C, 2voj:E
58 6k52:A 428 56 0.0578 0.0444 0.3393 2.2 6k54:A, 6k54:B, 6k54:C, 6k55:A, 6k55:B, 6k55:C
59 3zwa:A 727 132 0.1003 0.0454 0.2500 2.3 5mgb:A, 5mgb:B, 5omo:A, 5omo:B, 2x58:A, 2x58:B, 6z5f:AAA, 6z5f:BBB, 6z5o:AAA, 6z5v:AAA, 6z5v:BBB, 6zib:AAA, 6zib:BBB, 6zic:AAA, 6zic:BBB, 3zw9:A, 3zw9:B, 3zwa:B, 3zwb:A, 3zwb:B, 3zwc:A, 3zwc:B
60 8e59:A 1230 42 0.0517 0.0138 0.4048 2.9 8e5a:A, 8e5b:A, 7uhf:A, 7uhg:A
61 2i9p:B 296 100 0.0790 0.0878 0.2600 3.1 2i9p:A, 2i9p:C, 2i9p:D
62 2f9w:A 249 50 0.0517 0.0683 0.3400 3.5 2f9w:B
63 8eoi:K 1116 34 0.0395 0.0116 0.3824 5.6
64 8wea:A 1206 34 0.0395 0.0108 0.3824 5.6
65 8fhs:A 1282 34 0.0395 0.0101 0.3824 5.6 8eog:K, 8fd7:K, 8hlp:A, 8hma:E, 8hmb:D, 8we6:A, 8we7:A, 8we8:A, 8we9:A
66 5t5i:A 569 101 0.0790 0.0457 0.2574 6.6 5t5i:I, 5t5m:A, 5t61:A, 5t61:G, 5t61:M, 5t61:S, 5t61:Y, 5t61:e, 5t61:k, 5t61:q
67 2cvz:C 289 94 0.0881 0.1003 0.3085 9.4 2cvz:A, 2cvz:B, 1wp4:A, 1wp4:B, 1wp4:C, 1wp4:D

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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