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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLPKAFLSRMAELLGEEFPAFLKALTEGKRTYGLRVNTLKLPPEAFQRISPWPLRPIPWCQEGFYYPEEARPGPHPFFYA
GLYYIQEPSAQAVGVLLDPKPGERVLDLAAAPGGKTTHLAARMGGKGLLLANEVDGKRVRGLLENVERWGAPLAVTQAPP
RALAEAFGTYFHRVLLDAPCSGEGMFRKDREAARHWGPSAPKRMAEVQKALLAQASRLLGPGGVLVYSTCTFAPEENEGV
VAHFLKAHPEFRLEDARLHPLFAPGVPEWGEGNPELLKTARLWPHRLEGEGHFLARFRKEGGAWSTPRLERPSPLSQEAL
RAFRGFLEEAGLTLEGPVLDRAGHLYLLPEGLPTLLGLKAPAPGLYLGKVQKGRFLPARALALAFGATLPWPEGLPRLAL
TPEDPRALAFATGEGVAWEGEDHPLALVVLKTAAGEFPLDFGKAKRGVLRPVGVGLRSHH

The query sequence (length=460) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3m6w:A 460 460 1.0000 1.0000 1.0000 0.0 3m6v:A, 3m6v:B
2 2yxl:A 443 307 0.2326 0.2415 0.3485 2.86e-43
3 8v87:q 371 287 0.2087 0.2588 0.3345 5.24e-38 6elz:q, 6em5:q, 7nac:q, 7ohr:q, 7r7a:q, 7r7c:q, 8v83:q, 8v84:q
4 8fkt:SY 378 304 0.2239 0.2725 0.3388 1.50e-34 8fku:SY, 8fkv:SY, 8fkw:SY, 8fkx:SY, 8fky:SY
5 8esq:q 341 309 0.2196 0.2962 0.3269 5.47e-34
6 8i9w:CP 356 311 0.2370 0.3062 0.3505 1.56e-31 8i9r:CP, 8i9t:CP, 8i9v:CP, 8i9x:CP, 8i9y:CP, 8i9z:CP, 8ia0:CP
7 3a4t:A 258 276 0.1783 0.3178 0.2971 7.46e-30 3a4t:B
8 5zve:B 384 225 0.1630 0.1953 0.3333 1.57e-28 5zve:A, 5zvg:B, 5zvg:A, 5zvh:B, 5zvh:A
9 5zve:B 384 79 0.0587 0.0703 0.3418 1.0 5zve:A, 5zvg:B, 5zvg:A, 5zvh:B, 5zvh:A
10 8esr:q 260 280 0.1891 0.3346 0.3107 2.32e-27
11 1sqf:A 425 242 0.1761 0.1906 0.3347 5.38e-25
12 5wwr:A 461 185 0.1522 0.1518 0.3784 9.82e-22 5wwr:B, 5wws:A, 5wws:B, 5wwt:A, 5wwt:B
13 2b9e:A 275 223 0.1565 0.2618 0.3229 6.57e-20
14 7r6k:q 177 206 0.1391 0.3616 0.3107 4.87e-17
15 7of5:C 338 175 0.1196 0.1627 0.3143 4.46e-13 7of0:C, 7of3:C, 7of7:C
16 7pd3:x 366 175 0.1196 0.1503 0.3143 5.61e-13 4fp9:A, 4fp9:C, 4fp9:D, 4fp9:F, 4fzv:A, 7o9k:A1, 7o9m:A1, 7odr:x, 7ods:x, 7odt:x, 7oic:x, 8pk0:x, 8qsj:x
17 1eiz:A 180 35 0.0348 0.0889 0.4571 0.004 1ej0:A
18 4dmg:A 385 155 0.0891 0.1065 0.2645 0.21 4dmg:B
19 2pwy:A 251 45 0.0435 0.0797 0.4444 0.23 5c0o:E, 5c0o:F, 5c0o:G, 5c0o:H, 2pwy:B
20 2cww:B 382 162 0.0957 0.1152 0.2716 0.33 2cww:A
21 5oql:S 237 65 0.0413 0.0802 0.2923 0.61 6rxt:CB, 6rxu:CB, 6rxv:CB, 6rxx:CB, 6rxy:CB, 6rxz:CB
22 7mqa:SC 229 45 0.0370 0.0742 0.3778 0.67 2ipx:A, 7se7:A, 7se8:A, 7se8:B, 7se9:A, 7se9:B, 7sea:A, 7seb:A, 7sec:A, 7sec:B, 7sed:A
23 2yy8:A 174 75 0.0543 0.1437 0.3333 1.1 2yy8:B
24 3drw:A 460 90 0.0587 0.0587 0.3000 1.8 3drw:B
25 4y7o:A 239 63 0.0478 0.0921 0.3492 2.0 4y7l:A, 4y7o:B
26 2b25:A 254 54 0.0304 0.0551 0.2593 3.2 2b25:B
27 8e4i:B 769 182 0.1087 0.0650 0.2747 3.9 8e3j:A, 8e3j:B, 8e3p:A, 8e3p:B, 8e4i:A, 8e4k:A, 8e4k:B, 8e4z:A, 8e4z:B, 8e5u:A, 8e5u:B, 8e6g:A, 8e6g:B, 8ecw:A, 8ecw:B, 8egv:A, 8egv:B, 8ehp:A, 8ehp:B, 8eid:A, 8eid:B, 8ekn:A, 8ekn:B, 8ele:A, 8ele:B, 8epj:A, 8epj:B, 8epo:A, 8epo:B, 8epr:A, 8epr:B, 8eq7:A, 8eq7:B, 8eqx:A, 8eqx:B, 8er4:A, 8er4:B, 8etl:A, 8etl:B, 8eto:A, 8eto:B, 8eud:A, 8eud:B, 8eur:A, 8eur:B, 8eut:A, 8eut:B, 8eux:A, 8eux:B, 7r6j:A, 7r6j:B, 7rd2:A, 7rd2:B, 7rev:A, 7rev:B, 7t66:A, 7t66:B, 7t68:A, 7t68:B, 7t8v:A, 7t8v:B
28 4ywr:A 228 48 0.0304 0.0614 0.2917 3.9

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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