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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLIEIHMIQNHSPANLNRDDLGAPKTCYFGGVLRSRISSQCIKRSIRTSNDFKALLGGVRTRRLADLIQQEAGETECWKK
AQEILNKCGFKNKDDNTKMLVFMSKDKIKDLARIVLDNSLGLTEAAQQVANVIAQATLAPDIALCGRMLEPNDKDKDKKV
KWSNTTVEAALQVAHAISTHIARPEIDYFVAADDVPGEDAGAGHIGESMFASACFYKYFSIDWEQLVKNLKGDTNLAAHT
VGAFLLAAAKTNPSGKQNSFAAHNYPDGILVEFKNSPISYANAFVRPVSVVKESDLVEQSIGQLSNYVNDIRLGYYDEQS
PVIGFWFSPNNRYPLGYKHSKLASRNIGNLNELVGAVLDYIGGFKWEEVQ

The query sequence (length=370) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8yb6:G 377 370 1.0000 0.9814 1.0000 0.0 8yb6:D, 8yb6:E, 8yb6:F, 8yb6:H, 8yha:E, 8yha:F, 8yha:G, 8yha:H
2 8yha:D 355 370 0.9459 0.9859 0.9459 0.0
3 8yb6:I 268 228 0.5730 0.7910 0.9298 2.63e-153 8yha:I
4 8yb6:I 268 56 0.1514 0.2090 1.0000 2.59e-32 8yha:I
5 6c66:B 334 323 0.2784 0.3084 0.3189 5.43e-42
6 6c66:C 367 346 0.3027 0.3052 0.3237 6.97e-42 6c66:D, 6c66:E, 6c66:F, 5u07:E, 5u07:F, 5u07:G, 5u07:H, 5u0a:E, 5u0a:F, 5u0a:G, 5u0a:H
7 5cd4:F 363 332 0.2811 0.2865 0.3133 8.25e-38 5cd4:B, 5cd4:C, 5cd4:D, 5cd4:E, 5cd4:G, 5cd4:N, 5cd4:O, 5cd4:P, 5cd4:Q, 5cd4:R, 5cd4:S, 5h9e:E, 5h9e:F, 5h9e:G, 5h9e:H, 5h9e:I, 5h9f:E, 5h9f:F, 5h9f:G, 5h9f:H, 5h9f:I, 4qyz:D, 4qyz:E, 4qyz:F, 4qyz:G, 4qyz:H, 4tvx:F, 4tvx:D, 4tvx:E, 4tvx:C, 4tvx:B, 4tvx:G, 4tvx:R, 4tvx:P, 4tvx:Q, 4tvx:O, 4tvx:N, 4tvx:S, 4u7u:E, 4u7u:F, 4u7u:G, 4u7u:H, 4u7u:I, 4u7u:J, 4u7u:Q, 4u7u:R, 4u7u:S, 4u7u:T, 4u7u:U, 4u7u:V
8 5u07:D 260 173 0.1622 0.2308 0.3468 1.21e-23 5u0a:D
9 5u07:D 260 74 0.0892 0.1269 0.4459 8.03e-11 5u0a:D
10 4qyz:I 256 229 0.1919 0.2773 0.3100 5.54e-22
11 4qyz:I 256 56 0.0703 0.1016 0.4643 5.10e-09
12 5h9e:D 318 334 0.2486 0.2893 0.2754 6.64e-22 5h9f:D
13 6c66:H 329 345 0.2514 0.2827 0.2696 8.72e-21 5u07:I, 5u0a:I
14 2ykt:A 225 136 0.0757 0.1244 0.2059 0.11
15 6uek:D 585 111 0.0919 0.0581 0.3063 0.72
16 8tde:A 256 49 0.0405 0.0586 0.3061 2.5 8rr2:A, 8rr2:B
17 5j06:B 215 37 0.0378 0.0651 0.3784 2.9 7aw6:A, 7aw6:B, 6d49:A, 6d49:B, 6d4a:A, 6d4a:B, 5j06:D, 5j0b:A, 5j0b:B, 5j0b:C
18 7zpq:CA 1742 54 0.0486 0.0103 0.3333 2.9 7zrs:CA, 7zuw:CA
19 7p1g:M 347 45 0.0486 0.0519 0.4000 5.6 7p1g:K, 7p1g:L, 7p1g:N, 7p1g:O
20 8b45:B 30 21 0.0243 0.3000 0.4286 6.7 8b45:C, 8b45:D
21 4fnm:A 569 91 0.0595 0.0387 0.2418 7.0 5ch5:A, 5ivi:A, 5ivk:A, 4qwm:A, 5tyj:A, 5tyk:A, 5tyl:A, 5tym:A, 5tyn:A, 5tyo:A, 5typ:A, 4ubi:A, 4ubj:A, 4ubk:A, 4ubl:A, 4ubm:A, 4ubn:A, 4ubo:A, 4w1p:A, 4w1q:A, 4w1r:A, 4w1s:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218