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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLGLKTSIIGRRVIYFQEITSTNEFAKTSYLEEGTVIVADKQTMGHGRLNRKWESPEGGLWLSIVLSPKVPQKDLPKIVF
LGAVGVVETLKEFSIDGRIKWPNDVLVNYKKIAGVLVEGKGDKIVLGIGLNVNNKVPNGATSMKLELGSEVPLLSVFRSL
ITNLDRLYLNFLKNPMDILNLVRDNMILGVRVKILGDGSFEGIAEDIDDFGRLIIRLDSGEVKKVIYGDVSLRFL

The query sequence (length=235) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2deq:A 235 235 0.9957 0.9957 0.9957 8.91e-167 2deq:B, 2djz:A, 2djz:B, 2dkg:A, 2dkg:B, 2dth:A, 2dth:B, 2dti:A, 2dti:B, 2dto:A, 2dto:B, 2dve:A, 2dve:B, 2dxt:A, 2dxt:B, 2dxu:A, 2dxu:B, 2dz9:A, 2dz9:B, 2e41:A, 2e41:B, 2ejf:A, 2ejf:B, 2ejg:A, 2ejg:B, 2fyk:A, 2fyk:B, 1wnl:A, 1wnl:B, 1wpy:A, 1wpy:B, 1wqw:A, 1wqw:B, 1x01:A, 1x01:B, 2zgw:A, 2zgw:B
2 6ndl:A 323 239 0.3106 0.2260 0.3054 3.18e-28 6apw:A, 6aqq:A, 4dq2:A, 8eni:A, 4ha8:A, 6oru:A, 3rir:A, 3rkw:A, 3rky:A, 3v7c:A, 3v7r:A, 3v7s:A, 3v8k:A, 3v8l:A
3 3efr:A 233 233 0.3362 0.3391 0.3391 2.88e-26 3efr:B, 3efs:A, 3efs:B
4 2ej9:A 237 203 0.3106 0.3080 0.3596 5.36e-25
5 7dbs:A 252 172 0.2170 0.2024 0.2965 5.00e-16 6jhu:A
6 8fi3:B 308 237 0.3277 0.2500 0.3249 2.42e-15 8fi3:A
7 2ewn:A 318 235 0.3234 0.2390 0.3234 3.11e-15 2ewn:B, 1hxd:A, 1hxd:B, 4wf2:A
8 4xtu:A 266 223 0.3064 0.2707 0.3229 2.49e-14 4op0:A, 4op0:B, 3rux:A, 3rux:B, 4xtu:B, 4xtv:A, 4xtv:B, 4xtw:A, 4xtw:B, 4xtx:A, 4xtx:B, 4xty:A, 4xty:B, 4xtz:A, 4xtz:B, 4xu0:A, 4xu0:B, 4xu1:A, 4xu1:B, 4xu2:A, 4xu2:B, 4xu3:A, 4xu3:B
9 9j8e:B 296 242 0.2851 0.2264 0.2769 2.82e-14 9j8e:A
10 1bib:A 294 229 0.2894 0.2313 0.2969 5.45e-12
11 6ck0:B 210 123 0.1787 0.2000 0.3415 3.14e-09 6ck0:A
12 4fns:A 718 56 0.0766 0.0251 0.3214 1.9 4fns:B, 4fns:C, 4fns:D, 4fnt:C, 4fnt:B, 4fnt:A, 4fnt:D, 4fnu:A, 4fnu:B, 4fnu:C, 4fnu:D
13 8em4:A 3818 60 0.0766 0.0047 0.3000 3.3 8em4:B
14 8em7:A 4378 60 0.0766 0.0041 0.3000 3.3 8em7:B, 8jut:A, 8jut:B, 8juu:B, 8juu:A, 8jx8:B, 8jx8:A, 8jx9:B, 8jxa:A, 8jxb:A, 8jxd:A, 8jxe:A, 8jxe:B, 8jxf:B, 8jxg:A, 8jxh:A, 8jxi:B
15 6jmg:A 267 82 0.1021 0.0899 0.2927 4.2 6jmg:B
16 4kpp:A 395 67 0.0681 0.0405 0.2388 5.2 4kpp:B
17 3tii:B 313 56 0.0596 0.0447 0.2500 5.7 3tig:A, 3tii:A, 3tin:A
18 4xiw:C 239 62 0.0979 0.0962 0.3710 5.9 4xiw:A, 4xiw:B, 4xiw:D, 4xiw:E, 4xiw:F, 4xiw:G, 4xiw:H, 4xix:A, 4xix:B, 4xix:C, 4xix:D, 4xix:E, 4xix:F, 4xix:G, 4xix:H
19 6idn:A 272 81 0.1064 0.0919 0.3086 7.0

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218