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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLELLLLTSELYPDPVLPALSLLPHTVRTAPAEASSLLEAGNADAVLVDARNDLSSGRGLCRLLSSTGRSIPVLAVVSEG
GLVAVSADWGLDEILLLSTGPAEIDARLRLVVGLGKVSLGELVIDEGTYTARLRGRPLDLTYKEFELLKYLAQHAGRVFT
RAQLLHEVWGYDFFGGTRTVDVHVRRLRAKLGPEHEALIGTVRNVGYKAVRPA

The query sequence (length=213) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8hih:O 217 217 1.0000 0.9816 0.9816 8.55e-149 8hih:P, 8hih:N, 8hih:Q
2 8hig:A 98 101 0.3756 0.8163 0.7921 2.32e-52 8hig:B, 8hml:A, 8hml:B
3 6cqg:A 98 93 0.2300 0.5000 0.5269 7.92e-24
4 2oqr:A 226 196 0.3146 0.2965 0.3418 1.64e-23
5 7e1b:A 209 190 0.3427 0.3493 0.3842 2.28e-18 7e1b:B, 7e1b:C, 7e1b:H, 7e1b:D, 7e1b:E, 7e1b:F, 7e1b:G, 7e1h:A, 7e1h:B, 7e1h:E
6 4b09:A 218 192 0.2723 0.2661 0.3021 2.16e-17 4b09:B, 4b09:C, 4b09:D, 4b09:E, 4b09:F, 4b09:G, 4b09:I, 4b09:K
7 2gwr:A 225 178 0.2958 0.2800 0.3539 2.20e-17 3nhz:B, 3nhz:C, 3nhz:D
8 5ed4:E 224 197 0.2770 0.2634 0.2995 1.51e-16 5ed4:A, 5ed4:B, 5ed4:F, 2pmu:E
9 1ys6:B 227 95 0.2066 0.1938 0.4632 1.89e-16 1ys6:A, 1ys7:A, 1ys7:B
10 2z33:A 104 73 0.1596 0.3269 0.4658 2.73e-16 1gxp:A, 1gxp:B, 1gxp:E, 1gxp:F
11 8uvx:A 222 112 0.1690 0.1622 0.3214 3.44e-11 8uvk:A, 8uvk:B, 8uvx:B
12 4nhj:A 102 93 0.1690 0.3529 0.3871 5.93e-11 4nhj:B
13 8jo2:H 219 126 0.1925 0.1872 0.3254 6.02e-09 8jo2:I, 4s04:A, 4s04:B, 4s04:E, 4s04:F, 4s05:A, 4s05:B, 3w9s:A, 3w9s:B
14 5x5l:E 98 90 0.1408 0.3061 0.3333 7.75e-07 5x5l:B, 5x5l:H, 5x5l:A
15 6lxn:A 110 93 0.1315 0.2545 0.3011 8.78e-07 6lxn:B
16 4kny:B 226 146 0.1925 0.1814 0.2808 2.41e-06 4kfc:A, 4kfc:B, 4kny:A, 1zh2:A, 1zh2:B, 1zh4:A, 1zh4:B
17 5ju7:A 107 100 0.1408 0.2804 0.3000 1.34e-05
18 7lza:A 219 74 0.1221 0.1187 0.3514 2.71e-04 7lz9:A
19 7bkb:L 79 31 0.0469 0.1266 0.3226 0.82 7bkb:l, 7bkc:L, 7bkc:l
20 5cvi:B 215 37 0.0657 0.0651 0.3784 2.6 5cvi:A
21 5l4g:M 415 69 0.1080 0.0554 0.3333 3.0 5m32:g, 6msd:F, 6mse:F, 7qxw:F, 5t0c:AF, 5t0c:BF, 5t0g:F, 5t0h:F, 5t0i:F, 5t0j:F, 7w38:F, 7w39:F, 7w3a:F, 7w3i:F, 7w3j:F, 7w3k:F, 6wjd:F
22 2a5z:C 244 133 0.1596 0.1393 0.2556 4.8 2a5z:A, 2a5z:B
23 4zas:A 369 76 0.1221 0.0705 0.3421 5.2 4zas:B, 4zas:D, 4zas:E, 4zas:F
24 2jlb:A 548 47 0.0845 0.0328 0.3830 6.9 2jlb:B, 2vsn:A, 2vsn:B, 2xgm:A, 2xgm:B, 2xgo:A, 2xgs:A, 2xgs:B
25 6pd2:C 616 105 0.1408 0.0487 0.2857 8.1 6pd1:A, 6pd1:B, 6pd1:D, 6pd2:A, 6pd2:B, 6pd2:D
26 6ppo:B 235 51 0.0704 0.0638 0.2941 9.8 6psf:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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