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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLEAKFEEASLFKRIIDGFKDCVQLVNFQCKEDGIIAQAVDDSRVLLVSLEIGVEAFQEYRCDHPVTLGMDLTSLSKILR
CGNNTDTLTLIADNTPDSIILLFEDTKKDRIAEYSLKLMDIDADFLKIEELQYDSTLSLPSSEFSKIVRDLSQLSDSINI
MITKETIKFVADGDIGSGSVIIKPFVDMEHPETSIKLEMDQPVDLTFGAKYLLDIIKGSSLSDRVGIRLSSEAPALFQFD
LKSGFLQFFLAPKF

The query sequence (length=254) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6e49:C 254 254 1.0000 1.0000 1.0000 0.0 3v61:B
2 3k4x:A 758 253 0.9961 0.3338 1.0000 1.15e-176 6e49:B, 6e49:A, 2od8:A, 3v62:B, 3v62:E, 5zut:A
3 3k4x:A 758 253 0.9921 0.3325 0.9960 9.38e-176 6e49:B, 6e49:A, 2od8:A, 3v62:B, 3v62:E, 5zut:A
4 3k4x:A 758 252 0.9921 0.3325 1.0000 9.80e-176 6e49:B, 6e49:A, 2od8:A, 3v62:B, 3v62:E, 5zut:A
5 8gj5:B 257 254 0.4921 0.4864 0.4921 1.18e-88 8gj5:A, 8gj5:C, 8gjf:A, 8gjf:B, 8gjf:C
6 8q7i:A 257 254 0.4724 0.4669 0.4724 1.07e-83 7o1f:A, 7o1f:B, 7o1f:D, 7o1f:F, 8p9o:A
7 6qh1:C 242 252 0.4370 0.4587 0.4405 9.48e-76
8 6o09:F 262 254 0.4016 0.3893 0.4016 2.70e-70 6o09:C, 6o09:H, 6o09:A, 6o09:D, 6o09:K, 2zvv:B, 2zvv:A, 2zvw:A, 2zvw:B, 2zvw:C, 2zvw:D, 2zvw:E, 2zvw:F, 2zvw:G, 2zvw:H
9 1vyj:G 260 255 0.3504 0.3423 0.3490 7.06e-62 1axc:A, 1axc:C, 1axc:E, 6cbi:C, 6cbi:A, 6cbi:D, 6cbi:E, 8cob:A, 8cob:C, 8cob:E, 4d2g:C, 4d2g:B, 5e0u:A, 5e0u:B, 5e0u:C, 5e0v:A, 5e0v:B, 6eht:C, 6eht:B, 8f5q:A, 8f5q:C, 8f5q:E, 6gis:A, 8gl9:A, 8gl9:B, 8gla:A, 8gla:B, 6gws:C, 6gws:A, 6gws:B, 6hvo:B, 6hvo:C, 6hvo:A, 5iy4:A, 5iy4:C, 5iy4:E, 6k3a:A, 6k3a:C, 6k3a:E, 7kq0:A, 7kq0:C, 7kq0:E, 7kq1:A, 7kq1:C, 7kq1:E, 7m5l:A, 7m5l:B, 7m5l:C, 7m5m:A, 7m5m:B, 7m5n:B, 7m5n:A, 5mav:C, 5mav:A, 5mav:B, 5mav:F, 5mav:D, 5mav:E, 5mlo:A, 5mlo:C, 5mlo:E, 5mlw:A, 5mlw:C, 5mlw:E, 7nv0:D, 7nv1:D, 3p87:A, 3p87:D, 3p87:B, 3p87:C, 3p87:E, 3p87:F, 6qc0:A, 6qc0:C, 6qc0:E, 6qcg:C, 6qcg:B, 6qcg:F, 6qcg:A, 6qcg:D, 6qcg:E, 7qo1:F, 4rjf:A, 4rjf:C, 4rjf:E, 1u76:A, 1u76:C, 1u76:E, 1u7b:A, 3vkx:A, 1vyj:A, 1vyj:C, 1vyj:E, 1vyj:I, 1vyj:K, 3wgw:A, 3wgw:B, 5yco:A, 5yco:B, 5yco:C, 5yd8:Z, 5yd8:X, 5yd8:Y, 4ztd:B, 4ztd:A, 4ztd:C, 2zvk:A, 2zvk:B, 2zvk:C, 2zvl:A, 2zvl:B, 2zvl:C, 2zvl:D, 2zvl:E, 2zvl:F, 2zvm:A, 2zvm:B, 2zvm:C
10 6k2m:E 258 254 0.3583 0.3527 0.3583 1.09e-57 7wp3:A
11 1isq:A 240 249 0.2717 0.2875 0.2771 2.74e-20
12 5dai:A 247 253 0.2717 0.2794 0.2727 3.20e-20
13 6t7y:A 238 249 0.2559 0.2731 0.2610 1.14e-17
14 7rpw:C 245 253 0.2244 0.2327 0.2253 2.95e-13
15 1ud9:A 242 244 0.2047 0.2149 0.2131 9.47e-10 1ud9:B, 1ud9:C, 1ud9:D
16 1rxm:A 245 251 0.2323 0.2408 0.2351 2.46e-09 1rxz:A
17 2io4:B 246 255 0.2165 0.2236 0.2157 4.00e-09 2io4:D
18 2izo:C 244 262 0.2165 0.2254 0.2099 6.55e-04
19 3ppo:A 272 87 0.0906 0.0846 0.2644 0.61 3ppo:B, 3ppq:A, 3ppq:B, 3ppr:A, 3ppr:B
20 5hh9:A 390 53 0.0709 0.0462 0.3396 4.8 5hh9:B, 5i90:A, 5i90:B
21 6is1:B 121 51 0.0709 0.1488 0.3529 5.2 6is1:A, 6is1:C, 6is1:D, 6is1:E, 6is1:F, 6is1:G, 6is1:H, 6is2:A, 6is2:B, 6is2:C, 6is2:D, 6is3:C
22 2j17:B 145 56 0.0551 0.0966 0.2500 5.4 2j16:B, 2j17:A
23 4psx:B 361 41 0.0472 0.0332 0.2927 5.8 4psx:E
24 6djk:A 376 54 0.0551 0.0372 0.2593 6.9
25 4re6:A 577 32 0.0551 0.0243 0.4375 8.4 2hu5:A, 2hu5:B, 2hu7:A, 2hu7:B, 2hu8:A, 2hu8:B, 4re5:A, 4re5:B, 4re6:C, 1ve7:A, 1ve7:B
26 1z2m:A 152 80 0.0866 0.1447 0.2750 9.8 3phx:B
27 6ptr:B 372 135 0.1339 0.0914 0.2519 10.0 6ptr:A

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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