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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MLAFPKEFWWGGATSGPQSEGRFAKQHRNLFDYWYEEEPDLFYDYVGPDTASDAYHQIESDLTLLASLGHNSYRTSIQWT
RLIDDFEQATINPDGLAYYNRVIDACLANGIRPVINLHHFDLPIALYQAYGGWESKHVVDLFVAFSKVCFEQFGDRVKDW
FVHNEPMVVVEGSYLMQFHYPAIVDGKKAVQVAYNLALATAKVIQAYRRGPAELSDGRIGTILNLTPAYPASQSEADMAA
AHFAELWNNDLFMEAAVHGKFPEELVAVLKKDGVLWQSTPEELALIAENRVDYLGLNFYHPKRVKAPDAIPVISPSWSPE
WYYDPYLMPGHRMNVDKGWEIYPEAVYDIAIKMRDHYDNIPWFLSENGVGISGEDRYRDETGQIQDDYRIQFLKEHLTYL
HKGIEAGSNCFGYHVWTPIDGWSWLNAYKNRYGLVENNIHTQVRRPKASAYWFKKVATHNRLI

The query sequence (length=463) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 5foo:A 463 463 1.0000 1.0000 1.0000 0.0 5foo:B, 5foo:C, 5foo:D, 5foo:E, 5foo:F
2 5naq:A 461 460 0.5810 0.5835 0.5848 0.0 5naq:B, 5naq:C, 5naq:D, 5naq:E, 5naq:F
3 6z1m:A 423 468 0.3888 0.4255 0.3846 2.63e-97 6z1m:B, 6z1m:C
4 6z1h:A 382 464 0.3607 0.4372 0.3599 1.31e-88
5 8ivy:A 451 467 0.3326 0.3415 0.3298 8.92e-82 8ivy:B
6 4ptv:A 445 458 0.3218 0.3348 0.3253 4.98e-78 4ptv:B, 4ptw:A, 4ptw:B, 4ptx:A, 4ptx:B
7 2jal:B 444 462 0.3348 0.3491 0.3355 5.52e-75 2cbu:A, 2cbu:B, 2cbv:A, 2cbv:B, 2ces:A, 2ces:B, 2cet:A, 2cet:B, 2j75:A, 2j75:B, 2j77:A, 2j77:B, 2j78:A, 2j78:B, 2j79:A, 2j79:B, 2j7b:A, 2j7b:B, 2j7c:A, 2j7c:B, 2j7d:A, 2j7d:B, 2j7e:A, 2j7e:B, 2j7f:A, 2j7f:B, 2j7g:A, 2j7g:B, 2j7h:A, 2j7h:B, 2jal:A, 5n6s:A, 5n6s:B, 5n6s:C, 5n6s:D, 5n6t:A, 5n6t:B, 1oif:A, 1oif:B, 1oim:A, 1oim:B, 1oin:A, 1oin:B, 5oss:B, 1uz1:A, 1uz1:B, 2vrj:A, 2vrj:B, 1w3j:A, 1w3j:B, 2wbg:A, 2wbg:B, 2wbg:C, 2wbg:D, 2wc3:A, 2wc3:B, 2wc3:C, 2wc3:D, 2wc4:A, 2wc4:B, 2wc4:C, 2wc4:D
8 3wh6:A 443 456 0.3305 0.3454 0.3355 2.67e-73 5ayi:A, 3wh7:A, 3wh8:A
9 3ahv:A 472 471 0.3218 0.3157 0.3163 4.74e-73 3aht:A, 3aht:B, 3ahv:B, 7bzm:A, 7bzm:B, 3f4v:A, 3f4v:B, 3f5j:A, 3f5j:B, 3f5k:A, 3f5k:B, 3f5l:A, 3f5l:B, 4qlj:A, 4qlj:B, 4qlk:A, 4qlk:B, 4qll:A, 4qll:B, 2rgl:A, 2rgl:B, 2rgm:A, 2rgm:B, 3scn:A, 3scn:B, 3sco:A, 3sco:B, 3scp:A, 3scp:B, 3scq:A, 3scq:B, 3scr:A, 3scr:B, 3scs:A, 3scs:B, 3sct:A, 3sct:B, 3scu:A, 3scu:B, 3scv:A, 3scv:B, 3scw:A, 3scw:B
10 5yif:A 459 464 0.3305 0.3333 0.3297 4.03e-72 5yif:B
11 6qwi:A 448 470 0.3067 0.3170 0.3021 4.85e-71 1bgg:B, 1bgg:C, 1bgg:D, 1e4i:A, 6qwi:B, 6r4k:A, 6r4k:B, 1uyq:A
12 5gnx:A 451 466 0.3391 0.3481 0.3369 3.90e-70 5gnx:B, 5gny:A, 5gny:B, 5gny:C, 5gny:D, 5gnz:A, 5gnz:B, 5gnz:C, 5gnz:D, 5gnz:H, 5gnz:I, 5gnz:J, 5gnz:K
13 6jfp:A 444 461 0.3153 0.3288 0.3167 5.47e-70
14 4jie:A 484 470 0.3197 0.3058 0.3149 7.36e-70 4re2:A, 4re3:A, 4re4:A
15 4hz7:A 441 462 0.3024 0.3175 0.3030 1.73e-69 4hz8:A
16 8b80:A 474 475 0.3067 0.2996 0.2989 4.31e-67 8b81:A, 8b81:B, 5okb:B, 5okb:C, 5okb:D, 5oke:C, 5oke:D, 5oke:A, 5oke:B, 5okg:C, 5okg:D, 5okg:A, 5okg:B, 5okk:A, 5okk:B, 5okq:A, 5okq:B, 5okr:A, 5okr:B, 5oks:A, 5oks:B, 4zen:A, 4zen:B, 4zep:A, 4zep:B, 4zfm:D, 4zfm:A, 4zfm:B, 4zfm:C
17 7d6a:B 477 477 0.3175 0.3082 0.3082 6.78e-67 7d6a:A, 7d6b:A, 7d6b:B
18 1gnx:A 447 465 0.3197 0.3311 0.3183 2.39e-65 1gnx:B, 1gon:A
19 3wq5:A 475 474 0.3218 0.3137 0.3143 1.46e-63 3wq5:B, 3wq6:A, 3wq6:B
20 1v03:A 487 478 0.3153 0.2998 0.3054 7.38e-62
21 6m6l:B 445 458 0.3175 0.3303 0.3210 6.92e-61
22 1e55:A 492 488 0.3110 0.2927 0.2951 3.81e-60 1e1f:A, 1e1f:B, 1e4n:A, 1e4n:B, 1e55:B, 1e56:A, 1e56:B, 1h49:B, 1h49:A, 1v08:A, 1v08:B
23 3aiq:A 491 475 0.3024 0.2851 0.2947 4.14e-60 3air:A, 3ais:A, 3aiv:A, 3aiw:A
24 7wdo:A 445 462 0.3110 0.3236 0.3117 4.22e-60 7wdn:A, 7wdp:A, 7wdr:A, 7wds:A, 7wdv:A
25 6rjm:B 456 457 0.3024 0.3070 0.3063 1.26e-59 6rjm:A, 6rjo:A, 6rjo:B, 6rk2:A, 6rk2:B
26 3ptk:A 478 481 0.2959 0.2866 0.2848 1.48e-59 3ptk:B, 3ptm:A, 3ptm:B, 3ptq:A, 3ptq:B
27 5ns8:A 440 453 0.3024 0.3182 0.3091 2.75e-58 5ns8:B, 5ns8:C
28 4pbg:A 468 480 0.3089 0.3056 0.2979 1.18e-57 4pbg:B
29 2jie:A 445 476 0.2959 0.3079 0.2878 5.74e-57 2o9r:A, 2o9t:A, 2z1s:A
30 3gnr:A 478 478 0.2937 0.2845 0.2845 3.95e-55 3wba:A, 3wbe:A
31 3vif:A 473 488 0.3153 0.3087 0.2992 1.45e-53 3ahz:A, 3ai0:A, 3vig:A, 3vij:A, 3vik:A, 3vil:A, 3vim:A, 3vin:A, 3vio:A, 3vip:A
32 2jf6:B 472 469 0.2808 0.2754 0.2772 3.16e-53 2jf6:A, 3zj7:A, 3zj7:B, 3zj8:A, 3zj8:B
33 5yj7:C 490 463 0.2829 0.2673 0.2829 1.47e-52
34 4ipn:E 463 477 0.2873 0.2873 0.2788 1.32e-51 4ipn:B
35 4f66:A 478 488 0.3045 0.2950 0.2889 5.47e-51 4f66:B, 4f79:A, 4gpn:A, 4gpn:B
36 3qom:A 479 483 0.2959 0.2860 0.2836 6.58e-51
37 2e40:A 459 470 0.2937 0.2963 0.2894 1.66e-49 2e40:B
38 3u57:A 471 465 0.2851 0.2803 0.2839 1.02e-48 4atl:A, 4atl:B, 4ek7:A, 4ek7:B, 3u57:B, 3u5y:A, 3u5y:B, 3zj6:A, 3zj6:B
39 2e9l:A 466 483 0.2959 0.2940 0.2836 1.11e-45 2e9m:A, 3vkk:A, 2zox:A
40 7z1i:A 493 479 0.2916 0.2738 0.2818 1.25e-44 7z1i:B, 7z1i:D
41 3ahy:B 466 469 0.2916 0.2897 0.2878 1.22e-43 3ahy:A, 3ahy:C, 3ahy:D
42 7f1n:A 502 524 0.3002 0.2769 0.2653 4.37e-39 7f1n:B
43 1dwa:M 499 476 0.2765 0.2565 0.2689 2.66e-35 1dwf:M, 1dwg:M, 1dwh:M, 1dwi:M, 1dwj:M, 1e4m:M, 1e6q:M, 1e6s:M, 1e6x:M, 1e70:M, 1e71:M, 1e72:M, 1e73:M, 1myr:A, 1w9b:M, 1w9d:M, 2wxd:M
44 5van:A 861 208 0.1577 0.0848 0.3510 1.63e-30 6nfj:A, 6nfj:D, 5vaq:A
45 5van:A 861 272 0.1404 0.0755 0.2390 1.31e-11 6nfj:A, 6nfj:D, 5vaq:A
46 5van:A 861 111 0.0691 0.0372 0.2883 1.10e-06 6nfj:A, 6nfj:D, 5vaq:A
47 5w21:A 922 465 0.2635 0.1323 0.2624 1.47e-29 7ysh:A, 7ysu:A, 7ysw:A
48 5w21:A 922 429 0.2009 0.1009 0.2168 2.60e-10 7ysh:A, 7ysu:A, 7ysw:A
49 6m4f:C 543 470 0.2484 0.2118 0.2447 3.01e-24 6m4e:A, 6m4f:E, 6m55:A, 6m55:D
50 4ha3:A 489 500 0.2549 0.2413 0.2360 7.73e-23 4ha4:A
51 8kaq:D 364 166 0.1123 0.1429 0.3133 1.17e-20
52 8kaq:D 364 124 0.0626 0.0797 0.2339 3.21e-05
53 8kaq:A 401 169 0.1123 0.1297 0.3077 1.64e-20 8kaq:B, 8kaq:C
54 8kaq:A 401 124 0.0626 0.0723 0.2339 2.70e-05 8kaq:B, 8kaq:C
55 2ceq:A 489 380 0.1836 0.1738 0.2237 1.26e-19 2ceq:B, 2cer:A, 2cer:B, 4ean:A, 4ean:B, 5ixe:A, 5ixe:B, 1uwr:A, 1uwr:B, 1uws:B, 1uws:A, 1uwt:A, 1uwt:B, 1uwu:A, 1uwu:B, 7uz1:A, 7uz1:B, 7uz2:A, 7uz2:B
56 5d8z:A 324 76 0.0432 0.0617 0.2632 0.005 5d8z:B
57 3nco:A 313 68 0.0454 0.0671 0.3088 0.030 3nco:B, 3rjy:A
58 4kcf:A 407 68 0.0454 0.0516 0.3088 0.099 3m9v:A
59 1cen:A 334 61 0.0324 0.0449 0.2459 0.96
60 4q6w:A 376 114 0.0713 0.0878 0.2895 1.4 4q6w:B
61 4v2x:A 534 119 0.0626 0.0543 0.2437 1.4
62 7vt5:A 311 66 0.0389 0.0579 0.2727 1.5 7vt6:A, 7vt7:A
63 5h4r:A 375 135 0.0670 0.0827 0.2296 2.3
64 1r9d:A 786 58 0.0454 0.0267 0.3621 2.9 1r9d:B
65 3amg:B 291 58 0.0324 0.0515 0.2586 3.1
66 3amg:A 311 58 0.0324 0.0482 0.2586 3.2 3aof:B, 3aof:A, 3azr:A, 3azr:B, 3azs:A, 3azs:B, 3azt:A, 3azt:D, 3mmw:A, 3mmw:B, 3mmw:C, 3mmw:D
67 8ghy:A 362 101 0.0497 0.0635 0.2277 4.4 8ghy:B
68 6ub6:A 252 78 0.0367 0.0675 0.2179 5.7 6ub3:A, 6ub3:B, 6ub4:A, 6ub4:B, 6ub5:A
69 4iym:C 491 145 0.0842 0.0794 0.2690 7.2 4iym:A, 4iym:B, 4iym:D, 4iym:E, 4iym:F, 4iym:G, 4iym:H, 4iym:I, 4iym:J, 4iym:K, 4iym:L, 4iym:M, 4iym:N, 4iym:O, 4iym:P
70 6ubb:C 249 68 0.0389 0.0723 0.2647 9.8 6uba:A, 6uba:B, 6uba:C, 6uba:D, 6uba:E, 6uba:F, 6uba:G, 6uba:H, 6uba:I, 6uba:J, 6ubb:A, 6ubb:B, 6ubb:D, 6ubb:E, 6ubb:F, 6ubb:G, 6ubb:H, 6ubb:I, 6ubb:J

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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