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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKVSLAGQTVDVKKILNEIPKRTVTAALLEGGEIVAVEEADDEHAERKLVRRHDVEGKVVFVTARPCLYCARELAEAGVA
GVVYLGRGRGLGPYYLARSGVEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGFDADIAPAPEN
LSGRVEIMVTRGDPDEAVELLKEELPVFRIRRFLISGEFDRDELRERILEDIEPRILDPFAVRARIARAGAFSSSREAEV
FIGDVLTSVGREVNLNDPRTVVTVDVLGPRVSVGVEK

The query sequence (length=277) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 3g8q:A 278 277 1.0000 0.9964 1.0000 0.0 3g8q:B, 3g8q:C, 3g8q:D
2 2o7p:A 358 95 0.1155 0.0894 0.3368 0.008 2o7p:B, 2obc:A
3 1vq2:A 173 56 0.0650 0.1040 0.3214 0.026
4 6sle:B 261 43 0.0578 0.0613 0.3721 0.13
5 4p9c:A 136 46 0.0578 0.1176 0.3478 0.17 4p9c:B, 4p9c:C, 4p9c:D, 4p9c:E, 4p9c:F, 4p9c:G, 4p9c:H, 4p9c:I, 4p9c:J, 4p9c:K, 4p9c:L, 4p9d:A, 4p9d:B, 4p9d:C, 4p9d:D, 4p9d:E, 4p9d:F, 4p9e:A
6 8qhe:A 284 40 0.0578 0.0563 0.4000 0.47 6sle:A, 6sle:C, 6sle:H, 6sle:D, 6sle:E, 6sle:F, 6sle:G
7 2w4l:E 162 46 0.0505 0.0864 0.3043 0.54 2w4l:A, 2w4l:B, 2w4l:D, 2w4l:F
8 2hvw:A 147 25 0.0361 0.0680 0.4000 0.91 5c2o:A, 5c2o:B, 2hvv:A, 2hvv:B, 2hvw:B, 2hvw:C
9 7wnn:B 290 39 0.0505 0.0483 0.3590 0.94 7wnn:A, 7wnw:B, 7wnw:A
10 6eoi:B 287 37 0.0397 0.0383 0.2973 1.0 6eod:A, 6eod:H, 6eod:B, 6eod:G, 6eod:C, 6eod:D, 6eoh:A, 6eoh:B, 6eoi:A, 6h7p:A, 6h7p:B, 5ojl:A
11 2w4l:C 142 43 0.0469 0.0915 0.3023 1.4
12 2ywr:A 216 112 0.1083 0.1389 0.2679 2.4
13 2nx8:A 168 61 0.0542 0.0893 0.2459 2.4
14 6xtx:5 577 137 0.1300 0.0624 0.2628 2.5 6xty:5
15 1wwr:C 160 81 0.0903 0.1562 0.3086 2.9 1wwr:A, 1wwr:B, 1wwr:D
16 6ftx:W 878 31 0.0469 0.0148 0.4194 3.3 6g0l:W, 5j70:A, 5j70:B, 3mwy:W, 3ted:A
17 6g0l:M 855 31 0.0469 0.0152 0.4194 3.4 7nkx:W, 5o9g:W
18 7nz7:A 166 61 0.0614 0.1024 0.2787 3.7 3dh1:A, 3dh1:B, 3dh1:C, 3dh1:D, 7nz8:A, 7nz9:A
19 8aw3:2 177 46 0.0614 0.0960 0.3696 5.4
20 5a9t:A 286 42 0.0578 0.0559 0.3810 6.1 5a9s:A, 5a9s:B, 5fwn:A, 5fwn:B
21 2b3j:C 152 53 0.0578 0.1053 0.3019 6.7 2b3j:A, 2b3j:B, 2b3j:D
22 6idn:A 272 105 0.1047 0.1066 0.2762 7.5
23 7uo9:B 190 60 0.0650 0.0947 0.3000 8.2 7cxm:D, 7cxn:B, 7cxn:D, 7cyq:D, 7dok:G, 7dte:B, 7dte:D, 7ed5:D, 7ed5:B, 7egq:B, 7eiz:B, 7eiz:D, 8gw1:B, 8gwb:B, 8gwk:B, 8gwk:D, 8gwm:B, 8gwn:B, 7krn:D, 7krn:B, 7kro:D, 7kro:B, 7krp:D, 7krp:B, 7rdx:D, 7rdx:B, 7rdy:B, 7rdy:D, 7rdz:B, 7rdz:D, 7re0:B, 7re0:D, 7re1:B, 7re1:D, 7re2:D, 7re3:D, 7re3:H, 7re3:J, 8sq9:D, 8sqj:B, 8sqk:D, 7uo4:B, 7uo4:D, 7uo7:D, 7uo9:D, 7uob:B, 7uob:D, 7uoe:B, 7uoe:D, 6yyt:B, 6yyt:D
24 4c2c:A 433 73 0.0686 0.0439 0.2603 8.2 4c2d:A, 4c2d:B, 4c2d:C, 4c2f:A, 4c2g:A
25 1peg:A 266 24 0.0469 0.0489 0.5417 8.4 1ml9:A, 1peg:B

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218