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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKVPEAAISRLITYLRILEELEAQGVHRTSSEQLGGLAQVTAFQVRKDLSYFGSYGTRGVGYTVPVLKRELRHILGLNRK
WGLCIVGMGRLGSALADYPGFGESFELRGFFDVDPEKVGRPVRGGVIEHVDLLPQRVPGRIEIALLTVPREAAQKAADLL
VAAGIKGILNFAPVVLEVPKEVAVENVDFLAGLTRLSFAILNPKWREEMMG

The query sequence (length=211) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 2dt5:B 211 211 1.0000 1.0000 1.0000 5.60e-153 2dt5:A, 3ikt:A, 3ikt:B, 3il2:A, 3il2:B, 1xcb:A, 1xcb:B, 1xcb:C, 1xcb:D, 1xcb:E, 1xcb:F, 1xcb:G
2 5zz7:A 206 203 0.4218 0.4320 0.4384 7.47e-46 7wb3:A, 7wb3:B, 5zz6:A, 5zz6:B, 5zz6:C, 5zz6:D, 5zz7:B
3 2vt3:B 208 209 0.3555 0.3606 0.3589 6.15e-38 2vt2:A, 2vt2:B, 2vt3:A
4 3wgi:A 217 198 0.3886 0.3779 0.4141 6.00e-37 3wgg:A, 3wgg:B, 3wgh:A, 3wgh:B, 3wgi:B, 3wgi:C, 3wgi:D
5 3keo:B 207 202 0.3412 0.3478 0.3564 1.90e-34 3keo:A, 3keq:A, 3keq:B, 3ket:A
6 3e18:A 348 132 0.1327 0.0805 0.2121 0.016 3e18:B
7 7xdu:B 348 34 0.0616 0.0374 0.3824 1.5 7xdu:A
8 5f9t:A 659 41 0.0664 0.0212 0.3415 1.7 5f9t:B, 4yw1:A, 4yw1:B, 4yw2:A, 4yw2:B, 4yw3:A, 4yw3:B, 4yw5:A, 4yw5:B, 4yz2:A, 4yz2:B, 4yz3:A, 4yz3:B, 4yz4:A, 4yz4:B, 4yz5:A, 4yz5:B
9 6sy0:A 137 42 0.0711 0.1095 0.3571 1.8 6sy0:B
10 1o5k:A 295 57 0.0900 0.0644 0.3333 2.0
11 6xqn:C 154 43 0.0758 0.1039 0.3721 3.2 6x4s:A, 6x4s:B, 6x4s:C, 6x4s:D, 6xqn:D
12 3wv5:A 387 29 0.0616 0.0336 0.4483 7.2 3wvn:A
13 2fdc:A 505 84 0.0948 0.0396 0.2381 8.6
14 5m45:B 709 83 0.1090 0.0324 0.2771 9.4 5m45:E, 5m45:H, 5m45:K, 5svb:B, 5svb:E

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218