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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKVLFLTANEFEDVELIYPYHRLKEEGHEVYIASFERGTITGKHGYSVKVDLTFDKVNPEEFDALVLPGGRAPERVRLNE
KAVSIARKMFSEGKPVASICHGPQILISAGVLRGRKGTSYPGIKDDMINAGVEWVDAEVVVDGNWVSSRVPADLYAWMRE
FVKLLK

The query sequence (length=166) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 6f2f:A 166 166 1.0000 1.0000 1.0000 3.29e-122 6f2f:B, 6f2f:C, 6f2h:A, 6f2h:B, 6f2h:E, 6f2h:F, 6f2h:G, 6f2h:I, 6f2h:J, 6f2h:K, 6f2h:L, 6hf6:A, 6hf6:B, 6hf6:C
2 2vrn:A 185 168 0.3675 0.3297 0.3631 1.94e-31
3 6und:B 230 148 0.2108 0.1522 0.2365 6.11e-09 8tsn:A, 6und:A, 8vq1:A
4 3bwe:A 188 169 0.2590 0.2287 0.2544 9.74e-09 6af5:A, 6af9:A, 6afa:A, 6afb:A, 6afc:A, 6afd:A, 6afe:A, 6aff:A, 6afg:A, 6afh:A, 6afi:A, 6afj:A, 6afl:A, 3bwe:C, 3bwe:D, 3bwe:E, 3bwe:F, 4mnt:A, 4n0m:A, 4p35:A, 4p36:A, 7pa2:AAA, 7pa3:AAA, 8ppw:A, 8pq0:A
5 4k2h:D 186 153 0.2651 0.2366 0.2876 5.85e-07 4k2h:A, 4k2h:B, 4k2h:C, 4k2h:E, 4k2h:F, 4k2h:G, 4k2h:H, 4k2h:I, 4k2h:J, 4k2h:K, 4k2h:L, 4k2h:M, 4k2h:N
6 5xr2:C 295 144 0.1988 0.1119 0.2292 0.009 5xr3:E
7 4d1y:A 175 117 0.1747 0.1657 0.2479 0.020 3cne:A, 3cne:B, 3cne:C, 3cne:D, 4d1y:B
8 8hx8:A 673 69 0.1386 0.0342 0.3333 0.046 8hx6:A, 8hx6:B, 8hx7:A, 8hx7:B, 8hx8:B, 8hx9:B
9 4hxg:F 614 30 0.0904 0.0244 0.5000 0.41 4hxe:B, 4hxf:B, 4hxg:A, 4hxg:B, 4hxg:C, 4hxg:D, 4hxg:E, 4hxg:G, 4hxg:H, 4hxg:I, 4hxg:L
10 2nv2:J 196 48 0.1024 0.0867 0.3542 0.64 2nv2:B, 2nv2:D, 2nv2:F, 2nv2:H, 2nv2:L, 2nv2:N, 2nv2:P, 2nv2:R, 2nv2:T, 2nv2:V, 2nv2:X
11 4qnu:A 323 56 0.1265 0.0650 0.3750 1.1 4qnu:B, 4qnu:C, 4qnu:D, 4qnu:E, 4qnu:F, 4qnu:G, 4qnu:H, 4qnv:A, 4qnv:B
12 2ywc:A 475 56 0.1084 0.0379 0.3214 1.5 2ywc:B, 2ywc:C, 2ywc:D
13 2rir:E 298 47 0.0663 0.0369 0.2340 1.6 2rir:A, 2rir:B, 2rir:C, 2rir:D, 2rir:F, 2rir:G, 2rir:H
14 3o8o:B 763 77 0.1506 0.0328 0.3247 5.5 3o8o:D, 3o8o:F, 3o8o:H
15 1sy7:A 698 112 0.1325 0.0315 0.1964 6.2 1sy7:B
16 7lxi:A 279 69 0.1205 0.0717 0.2899 6.3 7mcj:A, 7mcj:B
17 2vxo:B 658 45 0.1024 0.0258 0.3778 6.8 2vxo:A
18 4rk5:A 275 49 0.0904 0.0545 0.3061 9.2 4rk4:A
19 1hqf:A 314 40 0.0843 0.0446 0.3500 9.3 1d3v:A, 1d3v:B, 3e8q:A, 3e8q:B, 3e8q:C, 3e8z:A, 3e8z:B, 3e8z:C, 3e9b:A, 3e9b:B, 3e9b:C, 1hq5:A, 1hq5:B, 1hqf:B, 1hqf:C, 1hqg:A, 1hqg:B, 1hqg:C, 1hqh:A, 1hqh:B, 1hqh:C, 1hqx:A, 1hqx:B, 1hqx:C, 1p8m:A, 1p8m:B, 1p8m:C, 1p8n:A, 1p8n:B, 1p8n:C, 1p8o:A, 1p8o:B, 1p8o:C, 1p8p:A, 1p8p:B, 1p8p:C, 1p8q:A, 1p8q:B, 1p8q:C, 1p8r:A, 1p8r:B, 1p8s:A, 1p8s:B, 1p8s:C, 1r1o:A, 1r1o:B, 1r1o:C, 1rla:A, 1rla:B, 1rla:C, 2rla:A, 2rla:B, 2rla:C, 3rla:A, 3rla:B, 3rla:C, 4rla:A, 4rla:B, 4rla:C, 5rla:A, 5rla:B, 5rla:C, 1t4p:A, 1t4p:B, 1t4p:C, 1t4r:A, 1t4r:B, 1t4r:C, 1t4s:A, 1t4s:B, 1t4s:C, 1t4t:A, 1t4t:B, 1t4t:C, 1t5f:A, 1t5f:B, 1t5f:C, 1t5g:A, 1t5g:B, 1t5g:C, 1ta1:A, 1ta1:B, 1ta1:C, 1tbh:A, 1tbh:B, 1tbh:C, 1tbj:A, 1tbj:B, 1tbj:C, 1tbl:A, 1tbl:B, 1tbl:C, 1zpe:A, 1zpe:B, 1zpe:C, 1zpg:A, 1zpg:B, 1zpg:C
20 3opy:B 884 82 0.1325 0.0249 0.2683 9.6 3opy:D, 3opy:F, 3opy:H

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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