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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKVGIDAGGTLIKIVQERTFKTELTKNIDQVVEWLNQQQIEKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKE
QGHDLADYIFANVGTGTSLHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIYKDTE
PPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTENIVYIGSSFHNNALLRKVVEDYTVLR
GCKPYYVENGAFSGAIGALYL

The query sequence (length=261) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 4m7x:A 273 265 1.0000 0.9560 0.9849 0.0 6avp:A, 6avp:C, 6avp:B, 6avp:D, 6awg:A, 6awg:B, 6awg:C, 6awg:D, 6awh:A, 6awh:B, 6awh:C, 6awh:D, 6awi:A, 6awi:B, 6awi:C, 6awi:D, 6awj:A, 6awj:B, 6awj:C, 6awj:D, 6ebv:A, 6ebv:B, 6ebv:C, 6ebv:D, 5elz:A, 2ews:A, 2ews:B, 5jic:A, 4m7y:A, 4m7y:B, 4nb4:A, 4nb4:B, 4nb4:C, 4nb4:D, 4nb4:E, 4nb4:F, 4nb4:G, 4nb4:H
2 5e26:B 362 178 0.1877 0.1354 0.2753 3.23e-11 5e26:A, 5e26:C, 5e26:D
3 5kqd:A 312 178 0.1954 0.1635 0.2865 4.43e-11
4 5kpr:A 359 267 0.2490 0.1811 0.2434 6.44e-11 6b3v:A, 2i7p:A, 2i7p:C, 2i7p:B, 2i7p:D, 5kpt:A, 5kpz:A, 5kq8:A, 3mk6:A, 3mk6:C, 3mk6:B, 3mk6:D, 6pe6:A, 3sms:A, 7ue3:A, 7ue4:A, 7ue5:A, 7ue6:A, 7ue7:A, 7ue8:A, 7ueo:A, 7uep:A, 7ueq:A, 7uer:A, 7ues:A, 7uet:A, 7ueu:A, 7uev:A, 7uex:A, 7uey:A, 6x4j:A, 6x4k:A, 6x4l:A
5 2i7n:A 325 178 0.1801 0.1446 0.2640 1.38e-09
6 3smp:B 363 178 0.1801 0.1295 0.2640 1.81e-09 2i7n:B, 3smp:A
7 7t1i:B 314 306 0.3065 0.2548 0.2614 7.83e-05 7t1g:B
8 7t1h:A 342 223 0.2261 0.1725 0.2646 0.045 7t1g:A, 7t1h:B, 7t1i:A, 6uj5:A
9 4fdg:B 592 50 0.0728 0.0321 0.3800 3.7 8eaf:A, 8eaf:B, 8eaf:C, 8eaf:D, 8eaf:E, 8eaf:F, 8eag:B, 8eag:C, 8eag:D, 8eag:E, 8eag:F, 8eag:A, 8eah:A, 8eah:B, 8eah:C, 8eah:D, 8eah:E, 8eah:F, 8eai:B, 8eai:C, 8eai:D, 8eai:E, 8eai:F, 8eai:A, 8eaj:A, 8eaj:B, 8eaj:C, 8eaj:D, 8eaj:E, 8eaj:F, 8eak:B, 8eak:C, 8eak:D, 8eak:E, 8eak:A, 8eak:F, 8eal:A, 8eal:B, 8eal:C, 8eal:D, 8eal:E, 8eal:F, 8eam:B, 8eam:C, 8eam:D, 8eam:E, 8eam:A, 8eam:F, 4fdg:A, 4fdg:C, 4fdg:D, 4fdg:E, 6mii:A, 6mii:B, 6mii:C, 6mii:D, 6mii:E, 6mii:F, 2vl6:A, 2vl6:B, 2vl6:C, 6wnz:B, 6wnz:A
10 8vjo:B 278 26 0.0498 0.0468 0.5000 4.8 9b9q:A, 9b9q:B, 9b9q:C, 7s2t:A, 7s2t:B, 7s2t:C, 7s4q:A, 7s4q:B, 7s4q:C, 8tk7:B, 8tk7:A, 8tk7:C, 8vjo:A, 8vjo:C
11 8ibv:R 279 30 0.0536 0.0502 0.4667 5.2 8ibu:R
12 7y38:Y 466 70 0.0728 0.0408 0.2714 5.9 6jim:A, 6jim:B
13 2e8y:A 712 92 0.0958 0.0351 0.2717 7.4 2e8y:B, 2e8z:A, 2e8z:B, 2e9b:A, 2e9b:B
14 4ke8:C 249 17 0.0383 0.0402 0.5882 8.3 4ke6:A, 4ke7:A, 4ke7:B, 4ke8:A, 4ke8:B, 4ke8:D, 4ke9:A, 4ke9:B, 4ke9:C, 4ke9:D
15 3urm:A 329 50 0.0690 0.0547 0.3600 9.0 3urm:B, 3uug:A, 3uug:B
16 4nmc:A 941 40 0.0613 0.0170 0.4000 9.1

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
  • yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218