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I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM DMFold SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

BioLiP
>protein
MKVELCSFSGYKIYPGHGRRYARTDGKVFQFLNAKCESAFLSKRNPRQINWTVLYRRKHKKGQSEEIQKKRTRRAVKFQR
AITGASLADIMAKRNQKPEVRKAQREQAIRAAKEAKKAKQA

The query sequence (length=121) is searched through a non-redundant set of database sequences protein_nr.fasta.gz clustered at 90% identity cutoff to identify representative hits. Homologs that belong to the same sequence cluster of the representative hit are listed in the last column of the table.

# Hit Hit
length
Aligned
length
Identity
(normalized by query)
Identity
(normalized by hit)
Identity (normalized
by aligned length)
E-value Homologs
to hit
1 8ifd:2Q 124 121 1.0000 0.9758 1.0000 1.02e-86 7a01:l2, 8a3d:Q, 5aj0:AW, 8b5l:W, 8b6c:W, 9bdl:AL24, 9bdn:AL24, 9bdp:AL24, 8bpo:V2, 8btk:BW, 7cpu:LW, 7cpv:LW, 4d5y:W, 4d67:W, 9f1b:BW, 9f1c:BW, 9f1d:BW, 7f5s:LW, 6frk:W, 6ftg:W, 6fti:W, 6ftj:W, 8g5y:LW, 8g5z:LW, 8g60:LW, 8g61:LW, 8g6j:LW, 8glp:LW, 6gz3:AW, 6gz4:AW, 6gz5:AW, 8ife:2Q, 6ip5:2Q, 6ip6:2Q, 6ip8:2Q, 3j7o:W, 3j7p:W, 3j7q:W, 3j7r:W, 3j92:W, 3jag:W, 3jah:W, 3jai:W, 3jaj:W, 3jan:W, 8jdj:b, 8jdk:b, 8jdl:b, 8jdm:b, 8k2c:LW, 5lks:LW, 6lqm:f, 6lsr:f, 7ls1:Q2, 7mdz:W, 7nfx:W, 7nwg:W, 7nwi:W, 7o7y:BW, 7o7z:BW, 7o80:BW, 7o81:BW, 7obr:W, 8ohd:LW, 8oj0:LW, 8oj5:LW, 8oj8:LW, 6ole:X, 6olf:X, 6olg:AW, 6oli:X, 6olz:AW, 6om0:X, 6om7:X, 7ow7:u, 7oya:W1, 7oyb:W1, 7oyc:W1, 7oyd:W, 8p2k:BW, 6p5i:AW, 6p5j:AW, 6p5k:AW, 6p5n:AW, 8q7z:BW, 8q87:BW, 8qfd:W, 7qgg:X, 8qoi:LW, 7qvp:LW, 7qvp:MW, 7qwq:W, 7qwr:W, 7qws:W, 6qzp:LW, 6r6p:W, 8rjb:W, 8rjc:W, 8rjd:W, 8scb:W, 6swa:U, 5t2c:Q, 6t59:W3, 7tm3:W, 7toq:AL24, 7tor:AL24, 7tut:W, 4ug0:LW, 4ujc:BW, 4ujd:AW, 4uje:CW, 4v6x:CW, 6w6l:X, 6xa1:LW, 7xnx:LW, 7xny:LW, 8xsx:LW, 8xsy:LW, 8xsz:LW, 6y0g:LW, 8y0w:LW, 8y0x:LW, 6y2l:LW, 6y57:LW, 6y6x:LW, 8yoo:LW, 8yop:LW, 6z6l:LW, 6z6m:LW, 6z6n:LW, 6zm7:LW, 6zme:LW, 6zmi:LW, 6zmo:LW, 6zvk:l2
2 7ls2:Q2 110 121 0.8843 0.9727 0.8843 6.03e-73 8bhf:J1, 6d90:W, 6d9j:W, 6hcf:W3, 6hcm:W3, 5lzs:W, 5lzt:W, 5lzu:W, 5lzv:W, 5lzw:W, 5lzx:W, 5lzy:W, 5lzz:W, 6mtb:W, 6mtc:W, 6mtd:W, 6mte:W, 7nwh:W, 6r5q:W, 6r6g:W, 6r7q:W, 6sgc:W2, 7ucj:W, 7uck:W, 7zjw:LZ, 7zjx:LZ
3 4v6w:CW 130 114 0.6612 0.6154 0.7018 1.60e-57 6xu6:CW, 6xu7:CW, 6xu8:CW
4 7olc:LW 133 112 0.5124 0.4662 0.5536 1.68e-39 7old:LW, 8oo0:LW, 7r81:Y1, 7z3n:LW, 7z3o:LW
5 5dat:n4 135 105 0.5124 0.4593 0.5905 5.20e-39 8aaf:J, 8agt:J, 8agu:J, 8agv:J, 8agw:J, 8agx:J, 8agz:J, 5apn:W, 5apo:W, 7azy:f, 7b7d:LS, 8bip:LW, 8bjq:LW, 8bn3:N4, 8bqd:AE, 8bqx:AE, 8ccs:I, 8cdl:I, 8cdr:I, 8ceh:I, 8cf5:I, 8cg8:I, 8cgn:I, 8civ:I, 8cku:I, 8cmj:I, 5dat:N4, 5dc3:N4, 5dc3:n4, 5dge:N4, 5dge:n4, 5dgf:N4, 5dgf:n4, 5dgv:N4, 5dgv:n4, 8eub:AW, 8evp:AW, 8evq:AW, 8evr:AW, 8evs:AW, 8evt:AW, 8ewb:AW, 8ewc:AW, 5fci:N4, 5fci:n4, 5fcj:N4, 5fcj:n4, 5gak:Y, 6gq1:W, 6gqb:W, 6gqv:W, 5h4p:W, 6hd7:Y, 6hhq:7, 6hhq:CY, 5i4l:N4, 5i4l:n4, 6i7o:AE, 6i7o:XE, 5it7:WW, 3j6x:64, 3j6y:64, 3j77:74, 3j78:74, 5juo:BA, 5jup:BA, 5jus:BA, 5jut:BA, 5juu:BA, 8k2d:LW, 8k82:LW, 5lyb:N4, 5lyb:n4, 5m1j:W5, 5mc6:AE, 5mei:7, 5mei:CY, 7mpi:AW, 7mpj:AW, 6n8m:j, 6n8n:j, 6n8o:j, 7n8b:AW, 5ndg:N4, 5ndv:N4, 5ndv:n4, 5ndw:N4, 5ndw:n4, 7nrc:LY, 7nrd:LY, 5obm:N4, 5obm:n4, 6oig:W, 5on6:7, 5on6:CY, 7osa:eL24, 7osm:eL24, 8p8m:QW, 8p8n:QW, 8p8u:QW, 8pfr:QW, 6q8y:AE, 6qik:v, 6qt0:v, 6qtz:v, 6r84:Y, 6r86:Y, 6r87:Y, 6ri5:v, 7rr5:LW, 6rzz:v, 6s05:v, 6s47:AY, 6snt:at, 6sv4:AE, 6sv4:XE, 6sv4:zE, 6t4q:LW, 5t62:j, 5t6r:j, 6t7i:LW, 6t7t:LW, 6t83:Wy, 6t83:H, 5tbw:7, 5tbw:CY, 6tb3:AE, 5tga:N4, 5tga:n4, 5tgm:N4, 5tgm:n4, 6tnu:AE, 7too:AL24, 7top:AL24, 4u3m:N4, 4u3m:n4, 4u3n:N4, 4u3n:n4, 4u3u:N4, 4u3u:n4, 4u4n:N4, 4u4n:n4, 4u4o:N4, 4u4o:n4, 4u4q:N4, 4u4q:n4, 4u4r:N4, 4u4r:n4, 4u4u:N4, 4u4u:n4, 4u4y:N4, 4u4y:n4, 4u4z:N4, 4u4z:n4, 4u50:N4, 4u50:n4, 4u51:N4, 4u51:n4, 4u52:N4, 4u52:n4, 4u53:N4, 4u53:n4, 4u55:N4, 4u55:n4, 4u56:N4, 4u56:n4, 4u6f:N4, 4u6f:n4, 6uz7:AW, 4v4b:BS, 4v6i:BZ, 4v7h:BS, 4v7r:BV, 4v7r:DV, 4v88:BW, 4v88:DW, 4v8t:W, 4v8y:BW, 4v8z:BW, 4v91:W, 6woo:W, 6xiq:W, 6xir:W, 8y0u:LW, 6z6j:LW, 6z6k:LW, 7zpq:BV, 7zrs:BV, 7zs5:BX, 7zuw:BV, 7zux:EV, 7zw0:LZ
6 5ndg:n4 118 105 0.4463 0.4576 0.5143 2.10e-29
7 8c3a:7 118 106 0.4380 0.4492 0.5000 5.35e-29 8c3a:BR, 8cq7:7, 8cq7:BR, 8cqw:7, 8cqw:BR, 8cre:7, 8cre:BR, 8oeq:7, 8oeq:BR, 7pzy:7, 7q08:7, 7q0f:7, 7q0p:7, 7q0r:7, 8q5i:7
8 9bh5:CW 88 99 0.4132 0.5682 0.5051 2.32e-27 9cai:CW
9 7bhp:LW 42 57 0.3471 1.0000 0.7368 1.27e-23
10 4v3p:LZ 75 73 0.2975 0.4800 0.4932 1.41e-20 8azw:L, 8b2l:L3, 8ip8:OA, 8ipa:OA, 8ipb:OA, 8jiv:CW, 4v7e:CW
11 7qiw:Y 62 61 0.2645 0.5161 0.5246 3.43e-20 7qiz:Y
12 5an9:G 69 65 0.2562 0.4493 0.4769 5.21e-20 5anb:G, 5anc:G, 6qkl:G
13 8fl2:SV 139 130 0.3471 0.3022 0.3231 2.56e-17 8fkp:SV, 8fkq:SV, 8fkr:SV, 8fks:SV, 8fkt:SV, 8fku:SV, 8fkv:SV, 8fkw:SV, 8fkx:SV, 8fky:SV, 8fkz:SV, 8fl0:SV, 8fl3:SV, 8fl4:SV, 8fl6:SV, 8fl7:SV, 8fl9:SV, 8fla:SV, 8flb:SV, 8flc:SV, 8fld:SV, 8fle:SV, 8flf:SV, 8idt:7, 8idy:7, 8ie3:7, 8ine:7, 8inf:7, 8ink:7, 8ipd:7, 8ipx:7, 8ipy:7, 8ir1:7, 8ir3:7, 6lss:7, 6lu8:7
14 8esq:u 114 91 0.2727 0.2895 0.3626 4.44e-17 8etc:u, 8eth:u, 8eti:u, 8etj:u, 8eug:u, 8eui:u
15 8esr:u 101 72 0.2479 0.2970 0.4167 8.39e-17
16 5xxb:V 63 62 0.2397 0.4603 0.4677 7.44e-16
17 5a2q:w 62 32 0.2645 0.5161 1.0000 3.79e-15
18 4v8m:BY 100 94 0.3058 0.3700 0.3936 1.61e-14 8ova:BY, 8ove:BY, 5t5h:Y
19 8br8:LX 63 62 0.2231 0.4286 0.4355 1.66e-14 8brm:LX, 8bsi:LX, 8bsj:LX, 8btd:LX, 8btr:LX
20 3j79:0 62 61 0.2314 0.4516 0.4590 1.65e-13 3jbn:A0, 3jbo:A0, 3jbp:A0, 8tpu:A0, 5umd:0
21 6zj3:Lm 66 65 0.2397 0.4394 0.4462 1.72e-13
22 8rxh:LX 85 94 0.2810 0.4000 0.3617 2.15e-13 8a3w:X, 8a98:X, 6az3:X, 3jcs:X, 8ovj:X, 8rxx:LX, 5t2a:W
23 7ohx:u 100 57 0.1983 0.2400 0.4211 3.83e-13 7oht:u
24 8hfr:tB 154 57 0.1983 0.1558 0.4211 4.27e-13 7bt6:u, 7btb:u, 6c0f:u, 6elz:u, 6em1:u, 6ft6:u, 3jct:u, 6m62:u, 6n8j:u, 6n8k:u, 6n8l:u, 7nac:u, 7naf:u, 7of1:u, 7oh3:u, 7ohq:u, 7ohr:u, 7ohs:u, 7ohu:u, 7ohv:u, 7ohy:u, 7r7a:u, 7u0h:u, 7ug6:u, 7uoo:u, 7uqb:u, 7uqz:u, 7v08:u, 8v83:u, 8v84:u, 8v87:u, 6ylg:u, 6ylh:u, 6ylx:u, 6yly:u, 7z34:u
25 7pwg:W 65 52 0.2149 0.4000 0.5000 1.47e-12 8fru:W, 7pwo:W2
26 8pv1:CQ 183 57 0.2066 0.1366 0.4386 2.35e-12 8i9r:CQ, 8i9t:CQ, 8i9v:CQ, 8i9w:CQ, 8i9x:CQ, 8i9y:CQ, 8i9z:CQ, 8ia0:CQ, 8pv2:CQ, 8pv3:CQ, 8pv4:CQ, 8pv5:CQ, 8pv6:CQ, 8pv7:CQ, 8pv8:CQ, 8pvk:CQ, 8pvl:CQ
27 5xy3:W 59 59 0.2149 0.4407 0.4407 1.78e-11
28 4v4n:AV 66 51 0.1818 0.3333 0.4314 1.22e-10 6skf:BY, 6skg:BY, 6th6:BY, 4v6u:BV
29 6zu5:LW0 93 73 0.2231 0.2903 0.3699 6.78e-10
30 4v8p:BT 61 55 0.1983 0.3934 0.4364 4.23e-09 4v8p:CT, 4v8p:ET, 4v8p:GT
31 8hku:L24E 54 48 0.1653 0.3704 0.4167 5.49e-09 8hkv:L24E, 8hky:L24E, 8hkz:L24E, 8hl1:L24E, 8hl2:L24E, 8hl3:L24E, 8hl4:L24E, 8hl5:L24E
32 4v9f:U 56 51 0.1405 0.3036 0.3333 1.92e-05 3cc2:U, 3cc4:U, 3cc7:U, 3cce:U, 3ccj:U, 3ccl:U, 3ccm:U, 3ccq:U, 3ccr:U, 3ccs:U, 3ccu:U, 3ccv:U, 3cd6:U, 3cma:U, 3cme:U, 3cpw:T, 3cxc:T, 3g4s:U, 3g6e:U, 3g71:U, 3i55:U, 3i56:U, 1jj2:T, 1k73:V, 1k8a:V, 1k9m:V, 1kc8:V, 1kd1:V, 1kqs:T, 1m1k:V, 1m90:V, 1n8r:V, 1nji:V, 2otj:U, 2otl:U, 3ow2:T, 1q7y:V, 1q81:V, 1q82:V, 1q86:V, 2qa4:U, 2qex:U, 1qvf:T, 1qvg:T, 1s72:U, 4v4p:AR, 4v4r:BT, 4v4s:BT, 4v4t:BT, 1vq4:U, 1vq5:U, 1vq6:U, 1vq7:U, 1vq8:U, 1vq9:U, 1vqk:U, 1vql:U, 1vqm:U, 1vqn:U, 1vqo:U, 1vqp:U, 1w2b:T, 1yhq:U, 1yi2:U, 1yij:U, 1yit:U, 1yj9:U, 1yjn:U, 1yjw:U
33 7qep:N4 89 86 0.2149 0.2921 0.3023 0.44
34 6rm3:LW0 90 87 0.1983 0.2667 0.2759 0.77
35 5wgb:A 291 45 0.1405 0.0584 0.3778 1.6
36 4xdq:A 237 43 0.0909 0.0464 0.2558 3.6
37 3lvm:B 394 30 0.1240 0.0381 0.5000 4.3 3lvj:A, 3lvj:B, 3lvk:A, 3lvl:B, 3lvm:A, 1p3w:B, 1p3w:A
38 3wev:B 681 31 0.0992 0.0176 0.3871 4.7 3wev:A
39 4ad9:A 288 58 0.1405 0.0590 0.2931 5.9 4ad9:B, 4ad9:C, 4ad9:D, 4ad9:E, 4ad9:F

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Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).
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